PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension Y Cao, X Zhang, L Wang, Q Yang, Q Ma, J Xu, J Wang, L Kovacs, ... Proceedings of the National Academy of Sciences 116 (27), 13394-13403, 2019 | 175 | 2019 |
PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis Q Yang, J Xu, Q Ma, Z Liu, V Sudhahar, Y Cao, L Wang, X Zeng, Y Zhou, ... Nature communications 9 (1), 4667, 2018 | 124 | 2018 |
Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia L Wang, Y Cao, B Gorshkov, Y Zhou, Q Yang, J Xu, Q Ma, X Zhang, ... Pharmacological Research 146, 104292, 2019 | 123 | 2019 |
Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche Z Liu, J Xu, Q Ma, X Zhang, Q Yang, L Wang, Y Cao, Z Xu, A Tawfik, ... Science translational medicine 12 (555), eaay1371, 2020 | 98 | 2020 |
Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis Y Xu, Y Wang, S Yan, Y Zhou, Q Yang, Y Pan, X Zeng, X An, Z Liu, ... EMBO molecular medicine 9 (9), 1263-1278, 2017 | 83 | 2017 |
Inactivation of endothelial adenosine A2A receptors protects mice from cerebral ischaemia‐induced brain injury Y Zhou, X Zeng, G Li, Q Yang, J Xu, M Zhang, X Mao, Y Cao, L Wang, ... British Journal of Pharmacology 176 (13), 2250-2263, 2019 | 53 | 2019 |
Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia‐induced pulmonary hypertension L Wang, X Zhang, Y Cao, Q Ma, X Mao, J Xu, Q Yang, Y Zhou, R Lucas, ... British Journal of Pharmacology 178 (5), 1055-1072, 2021 | 38 | 2021 |
Loss of myeloid cell-specific SIRPα, but not CD47, attenuates inflammation and suppresses atherosclerosis B Singla, HP Lin, WM Ahn, J Xu, Q Ma, M Sghayyer, K Dong, ... Cardiovascular Research 118 (15), 3097-3111, 2022 | 36 | 2022 |
Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy Z Liu, H Shi, J Xu, Q Yang, Q Ma, X Mao, Z Xu, Y Zhou, Q Da, Y Cai, ... JCI insight 7 (23), e160940, 2022 | 32 | 2022 |
ATIC-associated de novo purine synthesis is critically involved in proliferative arterial disease Q Ma, Q Yang, J Xu, X Zhang, D Kim, Z Liu, Q Da, X Mao, Y Zhou, Y Cai, ... Circulation 146 (19), 1444-1460, 2022 | 25 | 2022 |
Ablation of Myeloid ADK (Adenosine Kinase) Epigenetically Suppresses Atherosclerosis in ApoE−/− (Apolipoprotein E Deficient) Mice M Zhang, X Zeng, Q Yang, J Xu, Z Liu, Y Zhou, Y Cao, X Zhang, X An, ... Arteriosclerosis, thrombosis, and vascular biology 38 (12), 2780-2792, 2018 | 25 | 2018 |
Suppression of myeloid PFKFB3‐driven glycolysis protects mice from choroidal neovascularization Z Liu, X Mao, Q Yang, X Zhang, J Xu, Q Ma, Y Zhou, Q Da, Y Cai, ... British journal of pharmacology 179 (22), 5109-5131, 2022 | 24 | 2022 |
Endothelial adenosine kinase deficiency ameliorates diet-induced insulin resistance J Xu, Q Yang, X Zhang, Z Liu, Y Cao, L Wang, Y Zhou, X Zeng, Q Ma, ... Journal of Endocrinology 242 (2), 159-172, 2019 | 23 | 2019 |
Deficiency of myeloid Pfkfb3 protects mice from lung edema and cardiac dysfunction in LPS-induced endotoxemia J Xu, L Wang, Q Yang, Q Ma, Y Zhou, Y Cai, X Mao, Q Da, T Lu, Y Su, ... Frontiers in Cardiovascular Medicine 8, 745810, 2021 | 15 | 2021 |
Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models Q Ma, Q Yang, J Xu, HG Sellers, ZL Brown, Z Liu, Z Bordan, X Shi, D Zhao, ... European heart journal 44 (14), 1265-1279, 2023 | 10 | 2023 |
Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD‐fed mice Q Yang, Q Ma, J Xu, Z Liu, X Mao, Y Zhou, Y Cai, Q Da, M Hong, ... British journal of pharmacology 179 (8), 1661-1678, 2022 | 10 | 2022 |
Prkaa1 metabolically regulates monocyte/macrophage recruitment and viability in diet-induced murine metabolic disorders Q Yang, Q Ma, J Xu, Z Liu, J Zou, J Shen, Y Zhou, Q Da, X Mao, S Lu, ... Frontiers in Cell and Developmental Biology 8, 611354, 2021 | 10 | 2021 |
Hydrogen gas alleviates acute ethanol-induced hepatotoxicity in mice via modulating TLR4/9 innate immune signaling and pyroptosis L Xu, W Guo, J Dai, Y Cheng, Y Chen, W Liu, J Xu, W Su, X Zhang, ... International Immunopharmacology 127, 111399, 2024 | 9 | 2024 |
Disruption of endothelial Pfkfb3 ameliorates diet-induced murine insulin resistance Q Yang, J Xu, Q Ma, Z Liu, Y Zhou, Y Cai, X Mao, D Stepp, N Weintraub, ... Journal of Endocrinology 250 (3), 93-104, 2021 | 9 | 2021 |
A Novel Her2/VEGFR2/CD3 trispecific antibody with an optimal structural design showed improved T-cell-redirecting antitumor efficacy D Liu, X Qi, X Wei, L Zhao, X Wang, S Li, Z Wang, L Shi, J Xu, M Hong, ... Theranostics 12 (18), 7788, 2022 | 8 | 2022 |