PTH receptor-1 signalling—mechanistic insights and therapeutic prospects RW Cheloha, SH Gellman, JP Vilardaga, TJ Gardella Nature Reviews Endocrinology 11 (12), 712-724, 2015 | 246 | 2015 |
Backbone modification of a polypeptide drug alters duration of action in vivo RW Cheloha, A Maeda, T Dean, TJ Gardella, SH Gellman Nature biotechnology 32 (7), 653-655, 2014 | 134 | 2014 |
Enantioselective, ketoreductase-based entry into pharmaceutical building blocks: ethanol as tunable nicotinamide reductant S Broussy, RW Cheloha, DB Berkowitz Organic letters 11 (2), 305-308, 2009 | 103 | 2009 |
Exploring cellular biochemistry with nanobodies RW Cheloha, TJ Harmand, C Wijne, TU Schwartz, HL Ploegh Journal of Biological Chemistry 295 (45), 15307-15327, 2020 | 82 | 2020 |
A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes D Bousbaine, LI Fisch, M London, P Bhagchandani, ... Science 377 (6606), 660-666, 2022 | 79 | 2022 |
A new dehydrogenase from Clostridium acetobutylicum for asymmetric synthesis: dynamic reductive kinetic resolution entry into the Taxotere side chain GA Applegate, RW Cheloha, DL Nelson, DB Berkowitz Chemical Communications 47 (8), 2420-2422, 2011 | 57 | 2011 |
Improved GPCR ligands from nanobody tethering RW Cheloha, FA Fischer, AW Woodham, E Daley, N Suminski, ... Nature Communications 11 (1), 2087, 2020 | 52 | 2020 |
In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography AW Woodham, SH Zeigler, EL Zeyang, SC Kolifrath, RW Cheloha, ... Nature methods 17 (10), 1025-1032, 2020 | 43 | 2020 |
Backbone modification of a parathyroid hormone receptor-1 antagonist/inverse agonist RW Cheloha, T Watanabe, T Dean, SH Gellman, TJ Gardella ACS chemical biology 11 (10), 2752-2762, 2016 | 42 | 2016 |
A nanobody that recognizes a 14-residue peptide epitope in the E2 ubiquitin-conjugating enzyme UBC6e modulates its activity J Ling, RW Cheloha, N McCaul, ZYJ Sun, G Wagner, HL Ploegh Molecular immunology 114, 513-523, 2019 | 36 | 2019 |
Receptor selectivity from minimal backbone modification of a polypeptide agonist S Liu, RW Cheloha, T Watanabe, TJ Gardella, SH Gellman Proceedings of the National Academy of Sciences 115 (49), 12383-12388, 2018 | 36 | 2018 |
Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies J Xu, AR Kim, RW Cheloha, FA Fischer, JSS Li, Y Feng, E Stoneburner, ... Elife 11, e74326, 2022 | 34 | 2022 |
Nanobody–antigen conjugates elicit HPV-specific antitumor immune responses AW Woodham, RW Cheloha, J Ling, M Rashidian, SC Kolifrath, ... Cancer immunology research 6 (7), 870-880, 2018 | 31 | 2018 |
Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes RW Cheloha, JA Sullivan, T Wang, JM Sand, J Sidney, A Sette, ME Cook, ... ACS chemical biology 10 (3), 844-854, 2015 | 29 | 2015 |
Development of potent, protease-resistant agonists of the parathyroid hormone receptor with broad β residue distribution RW Cheloha, B Chen, NN Kumar, T Watanabe, RG Thorne, L Li, ... Journal of medicinal chemistry 60 (21), 8816-8833, 2017 | 24 | 2017 |
Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection VK Outlaw, RW Cheloha, EM Jurgens, FT Bovier, Y Zhu, DF Kreitler, ... Journal of the American Chemical Society 143 (15), 5958-5966, 2021 | 23 | 2021 |
Site-specifically conjugated single-domain antibody successfully identifies glypican-3–expressing liver cancer by immuno-PET S Fayn, AP King, NT Gutsche, Z Duan, J Buffington, CP Olkowski, Y Fu, ... Journal of Nuclear Medicine 64 (7), 1017-1023, 2023 | 21 | 2023 |
Converting an anti-mouse CD4 monoclonal antibody into an scFv positron emission tomography imaging agent for longitudinal monitoring of CD4+ T cells A Islam, N Pishesha, TJ Harmand, H Heston, AW Woodham, RW Cheloha, ... The Journal of Immunology 207 (5), 1468-1477, 2021 | 14 | 2021 |
Activity-based, bioorthogonal imaging of phospholipase D reveals spatiotemporal dynamics of GPCR-Gq signaling D Liang, RW Cheloha, T Watanabe, TJ Gardella, JM Baskin Cell chemical biology 29 (1), 67-73. e3, 2022 | 13 | 2022 |
Characterization of a Nanobody-Epitope Tag Interaction and Its Application for Receptor Engineering CC Cabalteja, S Sachdev, RW Cheloha ACS Chemical Biology 17 (8), 2296-2303, 2022 | 13 | 2022 |