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Ellen Mary McDonagh
Ellen Mary McDonagh
Genomics England / Queen Mary University London
Overená e-mailová adresa na: genomicsengland.co.uk
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Citované v
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Pharmacogenomics knowledge for personalized medicine
M Whirl‐Carrillo, EM McDonagh, JM Hebert, L Gong, K Sangkuhl, ...
Clinical Pharmacology & Therapeutics 92 (4), 414-417, 2012
21472012
100,000 genomes pilot on rare-disease diagnosis in health care—preliminary report
100,000 Genomes Project Pilot Investigators
New England Journal of Medicine 385 (20), 1868-1880, 2021
5442021
Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
M Ghoussaini, E Mountjoy, M Carmona, G Peat, EM Schmidt, A Hercules, ...
Nucleic acids research 49 (D1), D1311-D1320, 2021
4852021
Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process
K E Caudle, T E Klein, J M Hoffman, D J Muller, M Whirl-Carrillo, L Gong, ...
Current drug metabolism 15 (2), 209-217, 2014
4712014
The 100 000 Genomes Project: bringing whole genome sequencing to the NHS
C Turnbull, RH Scott, E Thomas, L Jones, N Murugaesu, FB Pretty, ...
Bmj 361, 2018
4572018
PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels
AR Martin, E Williams, RE Foulger, S Leigh, LC Daugherty, O Niblock, ...
Nature genetics 51 (11), 1560-1565, 2019
4542019
Open Targets Platform: supporting systematic drug–target identification and prioritisation
D Ochoa, A Hercules, M Carmona, D Suveges, A Gonzalez-Uriarte, ...
Nucleic acids research 49 (D1), D1302-D1310, 2021
3722021
The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
D Ochoa, A Hercules, M Carmona, D Suveges, J Baker, C Malangone, ...
Nucleic acids research 51 (D1), D1353-D1359, 2023
2522023
From pharmacogenomic knowledge acquisition to clinical applications: the PharmGKB as a clinical pharmacogenomic biomarker resource
EM McDonagh, M Whirl-Carrillo, Y Garten, RB Altman, TE Klein
Biomarkers in medicine 5 (6), 795-806, 2011
2122011
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA‐B) genotype and allopurinol dosing: 2015 update
Y Saito, LK Stamp, KE Caudle, MS Hershfield, EM McDonagh, ...
Clinical Pharmacology & Therapeutics 99 (1), 36-37, 2016
1672016
PharmGKB summary: caffeine pathway
CF Thorn, E Aklillu, EM McDonagh, TE Klein, RB Altman
Pharmacogenetics and genomics 22 (5), 389-395, 2012
1612012
The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor
A Meiser, A Mueller, EL Wise, EM McDonagh, SJ Petit, N Saran, PC Clark, ...
The Journal of Immunology 180 (10), 6713-6724, 2008
1612008
PharmGKB summary: very important pharmacogene information for: N:-acetyltransferase 2
EM McDonagh, S Boukouvala, E Aklillu, DW Hein, RB Altman, TE Klein
Pharmacogenetics and genomics 24 (8), 409-425, 2014
1592014
Human genetics evidence supports two-thirds of the 2021 FDA-approved drugs
D Ochoa, M Karim, M Ghoussaini, DG Hulcoop, EM McDonagh, I Dunham
Nat Rev Drug Discov 21 (8), 551, 2022
1522022
Nomenclature for alleles of the thiopurine methyltransferase gene
ML Appell, J Berg, J Duley, WE Evans, MA Kennedy, L Lennard, ...
Pharmacogenetics and genomics 23 (4), 242-248, 2013
1472013
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Rasburicase Therapy in the Context of G6PD Deficiency Genotype
MV Relling, EM McDonagh, T Chang, KE Caudle, HL McLeod, CE Haidar, ...
Clinical Pharmacology & Therapeutics 96 (2), 169-174, 2014
1452014
Whole genome sequencing for the diagnosis of neurological repeat expansion disorders in the UK: a retrospective diagnostic accuracy and prospective clinical validation study
K Ibañez, J Polke, RT Hagelstrom, E Dolzhenko, D Pasko, ERA Thomas, ...
The Lancet Neurology 21 (3), 234-245, 2022
1432022
CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3
A Mueller, A Meiser, EM McDonagh, JM Fox, SJ Petit, G Xanthou, ...
Journal of Leucocyte Biology 83 (4), 875-882, 2008
1372008
The gene curation coalition: a global effort to harmonize gene–disease evidence resources
MT DiStefano, S Goehringer, L Babb, FS Alkuraya, J Amberger, M Amin, ...
Genetics in Medicine 24 (8), 1732-1742, 2022
1022022
Opportunities and challenges for molecular understanding of ciliopathies–the 100,000 genomes project
G Wheway, Genomics England Research Consortium, HM Mitchison
Frontiers in genetics 10, 127, 2019
932019
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