Activation of TRPV1 mediates calcitonin gene-related peptide release, which excites trigeminal sensory neurons and is attenuated by a retargeted botulinum toxin with anti … J Meng, SV Ovsepian, J Wang, M Pickering, A Sasse, KR Aoki, ... Journal of Neuroscience 29 (15), 4981-4992, 2009 | 277 | 2009 |
Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder N Eissa, M Al-Houqani, A Sadeq, SK Ojha, A Sasse, B Sadek Frontiers in neuroscience 12, 304, 2018 | 268 | 2018 |
Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics J Wang, J Meng, GW Lawrence, TH Zurawski, A Sasse, MDO Bodeker, ... Journal of Biological Chemistry 283 (25), 16993-17002, 2008 | 136 | 2008 |
The rat H 3 receptor: gene organization and multiple isoforms S Morisset, A Sasse, F Gbahou, A Héron, X Ligneau, J Tardivel-Lacombe, ... Biochemical and biophysical research communications 280 (1), 75-80, 2001 | 92 | 2001 |
Role of neuroinflammation in autism spectrum disorder and the emergence of brain histaminergic system. Lessons also for BPSD? N Eissa, A Sadeq, A Sasse, B Sadek Frontiers in pharmacology 11, 886, 2020 | 88 | 2020 |
Cortagine, a specific agonist of corticotropin-releasing factor receptor subtype 1, is anxiogenic and antidepressive in the mouse model H Tezval, O Jahn, C Todorovic, A Sasse, K Eckart, J Spiess Proceedings of the National Academy of Sciences 101 (25), 9468-9473, 2004 | 88 | 2004 |
Self-assembled carrageenan/protamine polyelectrolyte nanoplexes—Investigation of critical parameters governing their formation and characteristics M Dul, KJ Paluch, H Kelly, AM Healy, A Sasse, L Tajber Carbohydrate Polymers 123, 339-349, 2015 | 65 | 2015 |
Acute stress facilitates trace eyeblink conditioning in C57BL/6 male mice and increases the excitability of their CA1 pyramidal neurons C Weiss, E Sametsky, A Sasse, J Spiess, JF Disterhoft Learning & Memory 12 (2), 138-143, 2005 | 53 | 2005 |
New histamine H3-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency A Sasse, B Sadek, X Ligneau, S Elz, HH Pertz, P Luger, CR Ganellin, ... Journal of medicinal chemistry 43 (17), 3335-3343, 2000 | 47 | 2000 |
Galloylquinic acid derivatives from Copaifera langsdorffii leaves display gastroprotective activity EVS Motta, M Lemos, JC Costa, VC Banderó-Filho, A Sasse, H Sheridan, ... Chemico-Biological Interactions 261, 145-155, 2017 | 40 | 2017 |
Novel partial agonists for the histamine H3 receptor with high in vitro and in vivo activity A Sasse, H Stark, S Reidemeister, A Hüls, S Elz, X Ligneau, CR Ganellin, ... Journal of medicinal chemistry 42 (20), 4269-4274, 1999 | 39 | 1999 |
Benefit of inhalation aromatherapy as a complementary treatment for stress and anxiety in a clinical setting–A systematic review F Hedigan, H Sheridan, A Sasse Complementary therapies in clinical practice 52, 101750, 2023 | 35 | 2023 |
(Partial) agonist/antagonist properties of novel diarylalkyl carbamates on histamine H 3 receptors A Sasse, H Stark, X Ligneau, S Elz, S Reidemeister, CR Ganellin, ... Bioorganic & medicinal chemistry 8 (5), 1139-1149, 2000 | 35 | 2000 |
Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity A Sasse, K Kiec-Kononowicz, H Stark, M Motyl, S Reidemeister, ... Journal of medicinal chemistry 42 (4), 593-600, 1999 | 35 | 1999 |
Benzophenone Derivatives and Related Compounds as Potent Histamine H3‐Receptor Antagonists and Potential PET/SPECT Ligands A Sasse, X Ligneau, B Sadek, S Elz, HH Pertz, CR Ganellin, JM Arrang, ... Archiv der Pharmazie 334 (2), 45-52, 2001 | 33 | 2001 |
influence of bulky substituents on histamine H3 receptor agonist/antagonist properties A Sasse, X Ligneau, A Rouleau, S Elz, CR Ganellin, JM Arrang, ... Journal of medicinal chemistry 45 (18), 4000-4010, 2002 | 27 | 2002 |
Traditional Chinese Medicine: From Aqueous Extracts to Therapeutic Formulae J Wang, A Sasse, H Sheridan Plant Extracts, 2019 | 25 | 2019 |
Polymorphisms and genetic linkage of histamine receptors S Micallef, H Stark, A Sasse Life sciences 93 (15), 487-494, 2013 | 25 | 2013 |
Design and implementation of an integrated competency-focused pharmacy programme: a case report TJ Ryan, T Grimes, MC Henman, EN Sheachnasaigh, M O’Dwyer, ... Pharmacy 7 (3), 121, 2019 | 23 | 2019 |
Antinociceptive and anti-inflammatory activities of Copaifera pubiflora Benth oleoresin and its major metabolite ent-hardwickiic acid GV Símaro, M Lemos, JJM da Silva, VP Ribeiro, C Arruda, AH Schneider, ... Journal of Ethnopharmacology 271, 113883, 2021 | 21 | 2021 |