Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules BJ Sung, K Yeon Hwang, Y Ho Jeon, JI Lee, YS Heo, J Hwan Kim, ... Nature 425 (6953), 98-102, 2003 | 341 | 2003 |
Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development YH Jeon, YS Heo, CM Kim, YL Hyun, TG Lee, S Ro, JM Cho Cellular and Molecular Life Sciences CMLS 62, 1198-1220, 2005 | 314 | 2005 |
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 YS Heo, SK Kim, CI Seo, YK Kim, BJ Sung, HS Lee, JI Lee, SY Park, ... The EMBO journal 23 (11), 2185-2195, 2004 | 313 | 2004 |
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane JS Park, WC Lee, KJ Yeo, KS Ryu, M Kumarasiri, D Hesek, M Lee, ... The FASEB Journal 26 (1), 219, 2012 | 237 | 2012 |
Solution structure of the activator contact domain of the RNA polymerase α subunit YH Jeon, T Negishi, M Shirakawa, T Yamazaki, N Fujita, A Ishihama, ... Science 270 (5241), 1495-1497, 1995 | 227 | 1995 |
Lactobacillus casei suppresses experimental arthritis by down-regulating T helper 1 effector functions JS So, HK Kwon, CG Lee, HJ Yi, JA Park, SY Lim, KC Hwang, YH Jeon, ... Molecular immunology 45 (9), 2690-2699, 2008 | 205 | 2008 |
Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering SC Lee, K Park, J Han, J Lee, HJ Kim, S Hong, W Heu, YJ Kim, JS Ha, ... Proceedings of the National Academy of Sciences 109 (9), 3299-3304, 2012 | 187 | 2012 |
Recent advances in the application of solution NMR spectroscopy to multi-span integral membrane proteins HJ Kim, SC Howell, WD Van Horn, YH Jeon, CR Sanders Progress in nuclear magnetic resonance spectroscopy 55 (4), 335-360, 2009 | 172 | 2009 |
Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway E Hwang, KS Ryu, K Pääkkönen, P Güntert, HK Cheong, DS Lim, JO Lee, ... Proceedings of the National Academy of Sciences 104 (22), 9236-9241, 2007 | 161 | 2007 |
Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism S An, KJ Yeo, YH Jeon, JJ Song Journal of Biological Chemistry 286 (10), 8369-8374, 2011 | 159 | 2011 |
The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein J Hwang, HW Suh, YH Jeon, E Hwang, LT Nguyen, J Yeom, SG Lee, ... Nature communications 5 (1), 2958, 2014 | 158 | 2014 |
Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis I Maslennikov, C Klammt, E Hwang, G Kefala, M Okamura, L Esquivies, ... Proceedings of the National Academy of Sciences 107 (24), 10902-10907, 2010 | 144 | 2010 |
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses D Sun, G Lee, JH Lee, HY Kim, HW Rhee, SY Park, KJ Kim, Y Kim, ... Nature structural & molecular biology 17 (10), 1188-1194, 2010 | 142 | 2010 |
Flexible linker in the RNA polymerase alpha subunit facilitates the independent motion of the C-terminal activator contact domain YH Jeon, T Yamazaki, T Otomo, A Ishihama, Y Kyogoku Journal of molecular biology 267 (4), 953-962, 1997 | 113 | 1997 |
Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein HR Lee, WC Choi, S Lee, J Hwang, E Hwang, K Guchhait, J Haas, Z Toth, ... Nature structural & molecular biology 18 (12), 1336-1344, 2011 | 95 | 2011 |
Structure of human PRL‐3, the phosphatase associated with cancer metastasis KA Kim, JS Song, JG Jee, MR Sheen, C Lee, TG Lee, S Ro, JM Cho, ... FEBS letters 565 (1-3), 181-187, 2004 | 92 | 2004 |
Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection YH Ahn, S Park, JJ Choi, BK Park, KH Rhee, E Kang, S Ahn, CH Lee, ... Nature microbiology 2 (1), 1-13, 2016 | 85 | 2016 |
Pyrazole derived ultra-short antimicrobial peptidomimetics with potent anti-biofilm activity M Ahn, P Gunasekaran, G Rajasekaran, EY Kim, SJ Lee, G Bang, K Cho, ... European journal of medicinal chemistry 125, 551-564, 2017 | 79 | 2017 |
Structural snapshots of heparin depolymerization by heparin lyase I YH Han, ML Garron, HY Kim, WS Kim, Z Zhang, KS Ryu, D Shaya, Z Xiao, ... Journal of Biological Chemistry 284 (49), 34019-34027, 2009 | 77 | 2009 |
Chemical inhibition of prometastatic lysyl-tRNA synthetase–laminin receptor interaction DG Kim, JY Lee, NH Kwon, P Fang, Q Zhang, J Wang, NL Young, M Guo, ... Nature chemical biology 10 (1), 29-34, 2014 | 76 | 2014 |