| Large clostridial toxins: mechanisms and roles in disease KE Orrell, RA Melnyk Microbiology and Molecular Biology Reviews 85 (3), 10.1128/mmbr. 00064-21, 2021 | 81 | 2021 |
| Intestinal bile acids directly modulate the structure and function of C. difficile TcdB toxin J Tam, S Icho, E Utama, KE Orrell, RF Gómez-Biagi, CM Theriot, HK Kroh, ... Proceedings of the National Academy of Sciences 117 (12), 6792-6800, 2020 | 78 | 2020 |
| Clostridium difficile toxins A and B: Receptors, pores, and translocation into cells KE Orrell, Z Zhang, SN Sugiman-Marangos, RA Melnyk Critical reviews in biochemistry and molecular biology 52 (4), 461-473, 2017 | 65 | 2017 |
| Spider wrapping silk fibre architecture arising from its modular soluble protein precursor ML Tremblay, L Xu, T Lefèvre, M Sarker, KE Orrell, J Leclerc, Q Meng, ... Scientific reports 5 (1), 11502, 2015 | 55 | 2015 |
| Nanoparticle self-assembly by a highly stable recombinant spider wrapping silk protein subunit L Xu, ML Tremblay, KE Orrell, J Leclerc, Q Meng, XQ Liu, JK Rainey FEBS letters 587 (19), 3273-3280, 2013 | 40 | 2013 |
| Structural and mechanical roles for the C-terminal nonrepetitive domain become apparent in recombinant spider aciniform silk L Xu, T Lefèvre, KE Orrell, Q Meng, M Auger, XQ Liu, JK Rainey Biomacromolecules 18 (11), 3678-3686, 2017 | 31 | 2017 |
| The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus KE Orrell, MJ Mansfield, AC Doxey, RA Melnyk Nature Communications 11 (1), 432, 2020 | 27 | 2020 |
| Tracking Transitions in Spider Wrapping Silk Conformation and Dynamics by 19F Nuclear Magnetic Resonance Spectroscopy M Sarker, KE Orrell, L Xu, ML Tremblay, JJ Bak, XQ Liu, JK Rainey Biochemistry 55 (21), 3048-3059, 2016 | 23 | 2016 |
| Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffold SN Sugiman-Marangos, SK Gill, MJ Mansfield, KE Orrell, AC Doxey, ... Communications Biology 5 (1), 375, 2022 | 11 | 2022 |
| Direct detection of membrane-inserting fragments defines the translocation pores of a family of pathogenic toxins KE Orrell, Å Tellgren-Roth, M Di Bernardo, Z Zhang, F Cuviello, ... Journal of molecular biology 430 (18), 3190-3199, 2018 | 7 | 2018 |
| Large clostridial toxins: mechanisms and roles in disease KE Orrell Microbiol Mol Biol Rev 85, 1, 2011 | 7 | 2011 |
| Interview with Dr. Chase Everett McMurren (Water Song Medicine Keeper) K Orrell, M Masrur University of Toronto Medical Journal 99 (3), 2022 | | 2022 |
| Interview with Ike Okafor K Orrell, J Oguntala University of Toronto Medical Journal 99 (2), 77-79, 2022 | | 2022 |
| Interview with Mandeep Mann and Setayesh Yazdani H Li, K Orrell University of Toronto Medical Journal 99 (1), 2022 | | 2022 |
| Translocation expands the scope of the large clostridial toxin family KE Orrell, RA Melnyk Trends in Biochemical Sciences 46 (12), 953-959, 2021 | | 2021 |
| Structure-function analysis of distant diphtheria toxin homologs reveals insights into host adaptation SN Sugiman-Marangos, SK Gill, MJ Mansfield, KE Orrell, AC Doxey, ... bioRxiv, 2021.08. 10.455837, 2021 | | 2021 |
| Biochemical and Genomic Insights into the Translocation of Large Clostridial Toxins across Host Cell Membranes KE Orrell University of Toronto (Canada), 2021 | | 2021 |