| The sequence of sequencers: The history of sequencing DNA JM Heather, B Chain Genomics 107 (1), 1-8, 2016 | 2118 | 2016 |
| Decombinator: a tool for fast, efficient gene assignment in T-cell receptor sequences using a finite state machine N Thomas, J Heather, W Ndifon, J Shawe-Taylor, B Chain Bioinformatics 29 (5), 542-550, 2013 | 128 | 2013 |
| High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities JM Heather, M Ismail, T Oakes, B Chain Briefings in Bioinformatics, bbw138, 2017 | 120 | 2017 |
| Quantitative characterisation of the T cell receptor repertoire of naïve and memory subsets using an integrated experimental and computational pipeline which is robust … T Oakes, JM Heather, K Best, R Byng-Maddick, C Husovsky, M Ismail, ... Frontiers in Immunology 8, 1267, 2017 | 116 | 2017 |
| Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation YY Lan, JM Heather, T Eisenhaure, CS Garris, D Lieb, R Raychowdhury, ... Aging cell 18 (2), e12901, 2019 | 114 | 2019 |
| Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding K Best, T Oakes, JM Heather, J Shawe-Taylor, B Chain Scientific reports 5, 2015 | 104 | 2015 |
| The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes PC de Greef, T Oakes, B Gerritsen, M Ismail, JM Heather, R Hermsen, ... Elife 9, e49900, 2020 | 96 | 2020 |
| Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy JM Heather, K Best, T Oakes, ER Gray, JK Roe, N Thomas, N Friedman, ... Frontiers in Immunology 6, 2015 | 86 | 2015 |
| Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires. M Cinelli, Y Sun, K Best, JM Heather, S Reich-Zeliger, E Shifrut, ... Bioinformatics (Oxford, England) 33 (7), 951, 2017 | 77 | 2017 |
| Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy DG Millar, RR Ramjiawan, K Kawaguchi, N Gupta, J Chen, S Zhang, ... Nature Biotechnology 38 (4), 420-425, 2020 | 71 | 2020 |
| Massively parallel interrogation and mining of natively paired human TCRαβ repertoires MJ Spindler, AL Nelson, EK Wagner, N Oppermans, JS Bridgeman, ... Nature Biotechnology 38 (5), 609-619, 2020 | 70 | 2020 |
| Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor K Flower, D Thomas, J Heather, S Ramasubramanyan, S Jones, ... PLoS One 6 (10), e25922, 2011 | 58 | 2011 |
| Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation AS Gkazi, BK Margetts, T Attenborough, L Mhaldien, JF Standing, ... Frontiers in Immunology 9, 2018 | 51 | 2018 |
| Specificity, privacy and degeneracy in the CD4 T cell receptor repertoire following immunisation. Y Sun, K Best, M Cinelli, S Reich-Zeliger, E Shifrut, N Friedman, ... Frontiers in Immunology 8, 430, 2017 | 51 | 2017 |
| The Epstein–Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1 J Heather, K Flower, S Isaac, AJ Sinclair Journal of General Virology 90 (6), 1450-1454, 2009 | 42 | 2009 |
| Validation of Immune Cell Modules in Multicellular Transcriptomic Data. G Pollara, MJ Murray, JM Heather, R Byng-Maddick, N Guppy, M Ellis, ... PloS one 12 (1), e0169271, 2017 | 35 | 2017 |
| Immune dysregulation in immunodeficiency disorders: The role of T-cell receptor sequencing GK Wong, JM Heather, S Barmettler, M Cobbold Journal of Autoimmunity, 2017 | 30 | 2017 |
| Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information JM Heather, MJ Spindler, MH Alonso, YI Shui, DG Millar, DS Johnson, ... Nucleic Acids Research 50 (12), e68-e68, 2022 | 29 | 2022 |
| Persistent T cell repertoire perturbation and T cell activation in HIV after long term treatment CT Turner, J Brown, E Shaw, I Uddin, E Tsaliki, JK Roe, G Pollara, Y Sun, ... Frontiers in immunology 12, 634489, 2021 | 24 | 2021 |
| Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency GK Wong, D Millar, S Penny, JM Heather, P Mistry, N Buettner, J Bryon, ... The Journal of Immunology 197 (5), 1642-1649, 2016 | 23 | 2016 |