admetSAR: a comprehensive source and free tool for assessment of chemical ADMET properties F Cheng, W Li, Y Zhou, J Shen, Z Wu, G Liu, PW Lee, Y Tang Journal of chemical information and modeling 52 (11), 3099-3105, 2012 | 2154 | 2012 |
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2 Y Zhou, Y Hou, J Shen, Y Huang, W Martin, F Cheng Cell discovery 6 (1), 14, 2020 | 1662 | 2020 |
Artificial intelligence in COVID-19 drug repurposing Y Zhou, F Wang, J Tang, R Nussinov, F Cheng The Lancet Digital Health 2 (12), e667-e676, 2020 | 546 | 2020 |
deepDR: a network-based deep learning approach to in silico drug repositioning X Zeng, S Zhu, X Liu, Y Zhou, R Nussinov, F Cheng Bioinformatics 35 (24), 5191-5198, 2019 | 445 | 2019 |
Alzheimer's disease drug development pipeline: 2023 J Cummings, Y Zhou, G Lee, K Zhong, J Fonseca, F Cheng Alzheimer's & Dementia: Translational Research & Clinical Interventions 9 (2 …, 2023 | 344 | 2023 |
Target identification among known drugs by deep learning from heterogeneous networks X Zeng, S Zhu, W Lu, Z Liu, J Huang, Y Zhou, J Fang, Y Huang, H Guo, ... Chemical Science 11 (7), 1775-1797, 2020 | 296 | 2020 |
Repurpose open data to discover therapeutics for COVID-19 using deep learning X Zeng, X Song, T Ma, X Pan, Y Zhou, Y Hou, Z Zhang, K Li, G Karypis, ... Journal of proteome research 19 (11), 4624-4636, 2020 | 240 | 2020 |
A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19 Y Zhou, Y Hou, J Shen, R Mehra, A Kallianpur, DA Culver, MU Gack, ... PLoS biology 18 (11), e3000970, 2020 | 212 | 2020 |
Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner D Bayik, Y Zhou, C Park, C Hong, D Vail, DJ Silver, A Lauko, G Roversi, ... Cancer discovery 10 (8), 1210-1225, 2020 | 201 | 2020 |
Deep learning-based prediction of drug-induced cardiotoxicity C Cai, P Guo, Y Zhou, J Zhou, Q Wang, F Zhang, J Fang, F Cheng Journal of chemical information and modeling 59 (3), 1073-1084, 2019 | 188 | 2019 |
Comprehensive characterization of protein–protein interactions perturbed by disease mutations F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ... Nature genetics 53 (3), 342-353, 2021 | 179 | 2021 |
Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment Y Zhou, J Xu, Y Hou, JB Leverenz, A Kallianpur, R Mehra, Y Liu, H Yu, ... Alzheimer's research & therapy 13 (1), 110, 2021 | 147 | 2021 |
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao, Y Luo, J Judd, ... Nature biotechnology 41 (1), 128-139, 2023 | 143 | 2023 |
Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer’s disease J Fang, P Zhang, Y Zhou, CW Chiang, J Tan, Y Hou, S Stauffer, L Li, ... Nature aging 1 (12), 1175-1188, 2021 | 141 | 2021 |
Prediction of chemical–protein interactions: multitarget-QSAR versus computational chemogenomic methods F Cheng, Y Zhou, J Li, W Li, G Liu, Y Tang Molecular BioSystems 8 (9), 2373-2384, 2012 | 136 | 2012 |
Adverse drug events: database construction and in silico prediction F Cheng, W Li, X Wang, Y Zhou, Z Wu, J Shen, Y Tang Journal of chemical information and modeling 53 (4), 744-752, 2013 | 129 | 2013 |
In silico assessment of chemical biodegradability F Cheng, Y Ikenaga, Y Zhou, Y Yu, W Li, J Shen, Z Du, L Chen, C Xu, ... Journal of chemical information and modeling 52 (3), 655-669, 2012 | 125 | 2012 |
Prediction of chemical-protein interactions network with weighted network-based inference method F Cheng, Y Zhou, W Li, G Liu, Y Tang PloS one 7 (7), e41064, 2012 | 113 | 2012 |
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity DC Watson, D Bayik, S Storevik, SS Moreino, SA Sprowls, J Han, ... Nature cancer 4 (5), 648-664, 2023 | 104 | 2023 |
Alzheimer's disease drug development pipeline: 2024 J Cummings, Y Zhou, G Lee, K Zhong, J Fonseca, F Cheng Alzheimer's & Dementia: Translational Research & Clinical Interventions 10 …, 2024 | 93 | 2024 |