| A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase DJ Hazuda, NJ Anthony, RP Gomez, SM Jolly, JS Wai, L Zhuang, ... Proceedings of the National Academy of Sciences 101 (31), 11233-11238, 2004 | 424 | 2004 |
| Chemical reactivity in solid-state pharmaceuticals: formulation implications SR Byrn, W Xu, AW Newman Advanced drug delivery reviews 48 (1), 115-136, 2001 | 327 | 2001 |
| Formation of isomorphic desolvates: creating a molecular vacuum GA Stephenson, EG Groleau, RL Kleemann, W Xu, DR Rigsbee Journal of pharmaceutical sciences 87 (5), 536-542, 1998 | 183 | 1998 |
| Solid-state NMR spectroscopy in pharmaceutical sciences M Li, W Xu, Y Su TrAC Trends in Analytical Chemistry 135, 116152, 2021 | 129 | 2021 |
| Mechanism of dissolution-induced nanoparticle formation from a copovidone-based amorphous solid dispersion P Harmon, K Galipeau, W Xu, C Brown, WP Wuelfing Molecular pharmaceutics 13 (5), 1467-1481, 2016 | 121 | 2016 |
| Characteristics of the human upper gastrointestinal contents in the fasted state under hypo-and A-chlorhydric gastric conditions under conditions of typical drug–drug … C Litou, M Vertzoni, C Goumas, V Vasdekis, W Xu, F Kesisoglou, ... Pharmaceutical research 33, 1399-1412, 2016 | 91 | 2016 |
| Development of amorphous solid dispersion formulations of a poorly water-soluble drug, MK-0364 S Sotthivirat, C McKelvey, J Moser, B Rege, W Xu, D Zhang International journal of pharmaceutics 452 (1-2), 73-81, 2013 | 90 | 2013 |
| Molecular interactions in posaconazole amorphous solid dispersions from two-dimensional solid-state NMR spectroscopy X Lu, C Huang, MB Lowinger, F Yang, W Xu, CD Brown, D Hesk, ... Molecular pharmaceutics 16 (6), 2579-2589, 2019 | 80 | 2019 |
| The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations MD Gelenter, KJ Smith, SY Liao, VS Mandala, AJ Dregni, MS Lamm, ... Nature structural & molecular biology 26 (7), 592-598, 2019 | 78 | 2019 |
| Effect of amorphous nanoparticle size on bioavailability of anacetrapib in dogs F Kesisoglou, M Wang, K Galipeau, P Harmon, G Okoh, W Xu Journal of pharmaceutical sciences 108 (9), 2917-2925, 2019 | 70 | 2019 |
| In situ characterization of pharmaceutical formulations by dynamic nuclear polarization enhanced MAS NMR QZ Ni, F Yang, TV Can, IV Sergeyev, SM D’Addio, SK Jawla, Y Li, ... The Journal of Physical Chemistry B 121 (34), 8132-8141, 2017 | 64 | 2017 |
| Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate CT John, W Xu, LK Lupton, PA Harmon Pharmaceutical research 30, 1628-1641, 2013 | 59 | 2013 |
| Understanding molecular mechanisms of biologics drug delivery and stability from NMR spectroscopy P Phyo, X Zhao, AC Templeton, W Xu, JK Cheung, Y Su Advanced Drug Delivery Reviews 174, 1-29, 2021 | 57 | 2021 |
| Structure determination of enalapril maleate form II from high-resolution X-ray powder diffraction data YH Kiang, A Huq, PW Stephens, W Xu Journal of pharmaceutical sciences 92 (9), 1844-1853, 2003 | 54 | 2003 |
| Identification of low abundant isomeric N-glycan structures in biological therapeutics by LC/MS J Zhao, S Li, C Li, SL Wu, W Xu, Y Chen, M Shameem, D Richardson, H Li Analytical chemistry 88 (14), 7049-7059, 2016 | 48 | 2016 |
| Advances and challenges in PBPK modeling–analysis of factors contributing to the oral absorption of atazanavir, a poorly soluble weak base M Berlin, A Ruff, F Kesisoglou, W Xu, MH Wang, JB Dressman European Journal of Pharmaceutics and Biopharmaceutics 93, 267-280, 2015 | 48 | 2015 |
| Three-dimensional NMR spectroscopy of fluorinated pharmaceutical solids under ultrafast magic angle spinning X Lu, D Skomski, KC Thompson, MJ McNevin, W Xu, Y Su Analytical Chemistry 91 (9), 6217-6224, 2019 | 43 | 2019 |
| In situ stimulated Raman scattering (SRS) microscopy study of the dissolution of sustained-release implant formulation AT Francis, TT Nguyen, MS Lamm, R Teller, SP Forster, W Xu, T Rhodes, ... Molecular pharmaceutics 15 (12), 5793-5801, 2018 | 42 | 2018 |
| Maintaining supersaturation of active pharmaceutical ingredient solutions with biologically relevant bile salts J Lu, JD Ormes, M Lowinger, AKP Mann, W Xu, JD Litster, LS Taylor Crystal Growth & Design 17 (5), 2782-2791, 2017 | 42 | 2017 |
| Atomic-level drug substance and polymer interaction in posaconazole amorphous solid dispersion from solid-state NMR X Lu, M Li, C Huang, MB Lowinger, W Xu, L Yu, SR Byrn, AC Templeton, ... Molecular pharmaceutics 17 (7), 2585-2598, 2020 | 40 | 2020 |
Yongchao SuPharmaceutical Sciences and Clinical Supply, Merck & Co., Inc.Overená e-mailová adresa na: merck.com
