Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases C Saraiva, C Praça, R Ferreira, T Santos, L Ferreira, L Bernardino Journal of controlled release 235, 34-47, 2016 | 1450 | 2016 |
MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease C Saraiva, J Paiva, T Santos, L Ferreira, L Bernardino Journal of Controlled Release 235, 291-305, 2016 | 188 | 2016 |
Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation SM Rocha, T Saraiva, AC Cristóvão, R Ferreira, T Santos, M Esteves, ... Journal of neuroinflammation 13, 1-16, 2016 | 108 | 2016 |
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality S Sabate‐Soler, SL Nickels, C Saraiva, E Berger, U Dubonyte, K Barmpa, ... Glia 70 (7), 1267-1288, 2022 | 106 | 2022 |
Gold nanostructures: Synthesis, properties, and neurological applications I Zare, MT Yaraki, G Speranza, AH Najafabadi, A Shourangiz-Haghighi, ... Chemical society reviews 51 (7), 2601-2680, 2022 | 85 | 2022 |
MicroRNA: basic concepts and implications for regeneration and repair of neurodegenerative diseases C Saraiva, M Esteves, L Bernardino Biochemical pharmacology 141, 118-131, 2017 | 75 | 2017 |
Parkinson's disease phenotypes in patient neuronal cultures and brain organoids improved by 2‐hydroxypropyl‐β‐cyclodextrin treatment J Jarazo, K Barmpa, J Modamio, C Saraiva, S Sabaté‐Soler, I Rosety, ... Movement Disorders 37 (1), 80-94, 2022 | 59 | 2022 |
MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease M Esteves, R Abreu, H Fernandes, C Serra-Almeida, PAT Martins, ... Molecular Therapy 30 (10), 3176-3192, 2022 | 50 | 2022 |
MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo C Saraiva, D Talhada, A Rai, R Ferreira, L Ferreira, L Bernardino, ... PLoS One 13 (3), e0193609, 2018 | 45 | 2018 |
Histamine modulates hippocampal inflammation and neurogenesis in adult mice C Saraiva, S Barata-Antunes, T Santos, E Ferreiro, AC Cristóvão, ... Scientific reports 9 (1), 8384, 2019 | 42 | 2019 |
Traceable microRNA-124 loaded nanoparticles as a new promising therapeutic tool for Parkinson's disease C Saraiva, L Ferreira, L Bernardino Neurogenesis 3 (1), e1256855, 2016 | 37 | 2016 |
Nanomedicine approaches to modulate neural stem cells in brain repair T Santos, C Boto, CM Saraiva, L Bernardino, L Ferreira Trends in biotechnology 34 (6), 437-439, 2016 | 35 | 2016 |
Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles T Santos, R Ferreira, E Quartin, C Boto, C Saraiva, J Bragança, J Peça, ... Acta biomaterialia 59, 293-302, 2017 | 29 | 2017 |
New insights into the regulatory roles of microRNAs in adult neurogenesis M Esteves, C Serra-Almeida, C Saraiva, L Bernardino Current Opinion in Pharmacology 50, 38-45, 2020 | 26 | 2020 |
Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications C Rebelo, T Reis, J Guedes, C Saraiva, AF Rodrigues, S Simões, ... Nature communications 13 (1), 4135, 2022 | 22 | 2022 |
Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation M Machado-Pereira, C Saraiva, L Bernardino, AC Cristóvão, R Ferreira Journal of Neuroinflammation 19 (1), 11, 2022 | 13 | 2022 |
Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids I Rosety, A Zagare, C Saraiva, S Nickels, P Antony, C Almeida, E Glaab, ... npj Parkinson's Disease 9 (1), 166, 2023 | 12 | 2023 |
Synaptic decline precedes dopaminergic neuronal loss in human midbrain organoids harboring a triplication of the SNCA gene J Modamio, C Saraiva, GG Giro, SL Nickels, J Jarazo, P Antony, P Barbuti, ... BioRxiv, 2021.07. 15.452499, 2021 | 10 | 2021 |
C-terminal binding proteins promote neurogenesis and Oligodendrogenesis in the subventricular zone C Serra-Almeida, C Saraiva, M Esteves, R Ferreira, T Santos, ... Frontiers in Cell and Developmental Biology 8, 584220, 2021 | 5 | 2021 |
CtBP Neuroprotective Role in Toxin-Based Parkinson’s Disease Models: From Expression Pattern to Dopaminergic Survival C Saraiva, J Lopes-Nunes, M Esteves, T Santos, A Vale, AC Cristóvão, ... Molecular neurobiology 60 (8), 4246-4260, 2023 | 4 | 2023 |