In vivo half-life of a protein is a function of its amino-terminal residue A Bachmair, D Finley, A Varshavsky science 234 (4773), 179-186, 1986 | 2588 | 1986 |
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein V Chau, JW Tobias, A Bachmair, D Marriott, DJ Ecker, DK Gonda, ... Science 243 (4898), 1576-1583, 1989 | 2064 | 1989 |
The N-end rule: functions, mysteries, uses. A Varshavsky Proceedings of the National Academy of Sciences 93 (22), 12142-12149, 1996 | 1214 | 1996 |
Split ubiquitin as a sensor of protein interactions in vivo. N Johnsson, A Varshavsky Proceedings of the National Academy of Sciences 91 (22), 10340-10344, 1994 | 1121 | 1994 |
The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses D Finley, E Özkaynak, A Varshavsky Cell 48 (6), 1035-1046, 1987 | 1062 | 1987 |
A proteolytic pathway that recognizes ubiquitin as a degradation signal ES Johnson, PCM Ma, IM Ota, A Varshavsky Journal of biological chemistry 270 (29), 17442-17456, 1995 | 1018 | 1995 |
The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis D Finley, B Bartel, A Varshavsky Nature 338 (6214), 394-401, 1989 | 901 | 1989 |
The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme S Jentsch, JP McGrath, A Varshavsky Nature 329 (6135), 131-134, 1987 | 887 | 1987 |
The N‐end rule pathway and regulation by proteolysis A Varshavsky Protein science 20 (8), 1298-1345, 2011 | 815 | 2011 |
Mapping proteinDNA interactions in vivo with formaldehyde: Evidence that histone H4 is retained on a highly transcribed gene MJ Solomon, PL Larsen, A Varshavsky Cell 53 (6), 937-947, 1988 | 805 | 1988 |
The ubiquitin system A Varshavsky Trends in biochemical sciences 22 (10), 383-387, 1997 | 801 | 1997 |
The N-end rule in bacteria JW Tobias, TE Shrader, G Rocap, A Varshavsky Science 254 (5036), 1374-1377, 1991 | 760 | 1991 |
A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome F Strauss, A Varshavsky Cell 37 (3), 889-901, 1984 | 750 | 1984 |
N-terminal acetylation of cellular proteins creates specific degradation signals CS Hwang, A Shemorry, A Varshavsky Science 327 (5968), 973-977, 2010 | 736 | 2010 |
The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein JP McGrath, A Varshavsky Nature 340 (6232), 400-404, 1989 | 725 | 1989 |
The N-end rule A Varshavsky Cold Spring Harbor symposia on quantitative biology 60, 461-478, 1995 | 702 | 1995 |
Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85 D Finley, A Ciechanover, A Varshavsky Cell 37 (1), 43-55, 1984 | 701 | 1984 |
Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85 A Ciechanover, D Finley, A Varshavsky Cell 37 (1), 57-66, 1984 | 687 | 1984 |
Formaldehyde-mediated DNA-protein crosslinking: a probe for in vivo chromatin structures. MJ Solomon, A Varshavsky Proceedings of the National Academy of Sciences 82 (19), 6470-6474, 1985 | 651 | 1985 |
The yeast ubiquitin genes: a family of natural gene fusions. E Ozkaynak, D Finley, MJ Solomon, A Varshavsky The EMBO journal 6 (5), 1429-1439, 1987 | 610 | 1987 |