The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity D Cox, DR Whiten, JWP Brown, MH Horrocks, R San Gil, CM Dobson, ... Journal of Biological Chemistry 293 (12), 4486-4497, 2018 | 132 | 2018 |
Proteomics approaches for biomarker and drug target discovery in ALS and FTD TJ Hedl, R San Gil, F Cheng, SL Rayner, J Davidson, A De Luca, ... Frontiers in Neuroscience 13, 548, 2019 | 91 | 2019 |
The heat shock response in neurons and astroglia and its role in neurodegenerative diseases R San Gil, L Ooi, JJ Yerbury, H Ecroyd Molecular neurodegeneration 12, 1-20, 2017 | 89 | 2017 |
TDP-43 pathology: From noxious assembly to therapeutic removal SS Keating, R San Gil, MEV Swanson, EL Scotter, AK Walker Progress in Neurobiology 211, 102229, 2022 | 52 | 2022 |
Rapid flow cytometric measurement of protein inclusions and nuclear trafficking DR Whiten, R San Gil, L McAlary, JJ Yerbury, H Ecroyd, MR Wilson Scientific Reports 6 (1), 31138, 2016 | 35 | 2016 |
Aggregation-prone TDP-43 sequesters and drives pathological transitions of free nuclear TDP-43 SS Keating, AT Bademosi, R San Gil, AK Walker Cellular and Molecular Life Sciences 80 (4), 95, 2023 | 26 | 2023 |
Riluzole does not ameliorate disease caused by cytoplasmic TDP‐43 in a mouse model of amyotrophic lateral sclerosis AL Wright, PA Della Gatta, S Le, BA Berning, P Mehta, KR Jacobs, H Gul, ... European Journal of Neuroscience 54 (6), 6237-6255, 2021 | 25 | 2021 |
Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD W Luan, AL Wright, H Brown-Wright, S Le, R San Gil, L Madrid San Martin, ... Molecular Psychiatry 28 (6), 2445-2461, 2023 | 19 | 2023 |
Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cells R San Gil, D Cox, L McAlary, T Berg, AK Walker, JJ Yerbury, L Ooi, ... Journal of Cell Science 133 (15), 2020 | 12 | 2020 |
Using bicistronic constructs to evaluate the chaperone activities of heat shock proteins in cells R San Gil, T Berg, H Ecroyd Scientific Reports 7 (1), 2387, 2017 | 9 | 2017 |
A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration R San Gil, D Pascovici, J Venturato, H Brown-Wright, P Mehta, ... Nature Communications 15 (1), 1508, 2024 | 8 | 2024 |
Regional differences in the inflammatory and heat shock response in glia: implications for ALS BE Clarke, R San Gil, J Yip, B Kalmar, L Greensmith Cell Stress and Chaperones 24 (5), 857-870, 2019 | 7 | 2019 |
Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 G93A Mice R San Gil, BE Clarke, H Ecroyd, B Kalmar, L Greensmith Cells 10 (5), 1257, 2021 | 3 | 2021 |
UndERACting ion channels in neurodegeneration MT Jacobs, R San Gil, AK Walker Trends in Neurosciences 47 (2), 87-89, 2024 | | 2024 |
First person-Rebecca San Gil R San Gil Journal of Cell Science 133 (15), 1-2, 2020 | | 2020 |
The role of the heat shock response in protein aggregation and neuroinflammation associated with neurodegenerative diseases R San Gil | | 2017 |