Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients D Worlitzsch, R Tarran, M Ulrich, U Schwab, A Cekici, KC Meyer, P Birrer, ... The Journal of clinical investigation 109 (3), 317-325, 2002 | 1669 | 2002 |
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease H Matsui, BR Grubb, R Tarran, SH Randell, JT Gatzy, CW Davis, ... Cell 95 (7), 1005-1015, 1998 | 1512 | 1998 |
Mucus clearance and lung function in cystic fibrosis with hypertonic saline SH Donaldson, WD Bennett, KL Zeman, MR Knowles, R Tarran, ... New England Journal of Medicine 354 (3), 241-250, 2006 | 883 | 2006 |
What are the respiratory effects of e-cigarettes? JE Gotts, SE Jordt, R McConnell, R Tarran bmj 366, 2019 | 593 | 2019 |
Normal and cystic fibrosis airway surface liquid homeostasis: the effects of phasic shear stress and viral infections R Tarran, B Button, M Picher, AM Paradiso, CM Ribeiro, ER Lazarowski, ... Journal of Biological Chemistry 280 (42), 35751-35759, 2005 | 431 | 2005 |
The CF salt controversy: in vivo observations and therapeutic approaches R Tarran, BR Grubb, D Parsons, M Picher, AJ Hirsh, CW Davis, ... Molecular cell 8 (1), 149-158, 2001 | 349 | 2001 |
The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition R Tarran, BR Grubb, JT Gatzy, CW Davis, RC Boucher The Journal of general physiology 118 (2), 223-236, 2001 | 335 | 2001 |
Regulation of normal and cystic fibrosis airway surface liquid volume by phasic shear stress R Tarran, B Button, RC Boucher Annu. Rev. Physiol. 68, 543-561, 2006 | 307 | 2006 |
Chronic e-cigarette exposure alters the human bronchial epithelial proteome A Ghosh, RC Coakley, T Mascenik, TR Rowell, ES Davis, K Rogers, ... American journal of respiratory and critical care medicine 198 (1), 67-76, 2018 | 283 | 2018 |
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration LA Clunes, CM Davies, RD Coakley, AA Aleksandrov, AG Henderson, ... The FASEB Journal 26 (2), 533, 2012 | 270 | 2012 |
Nucleotide release provides a mechanism for airway surface liquid homeostasis ER Lazarowski, R Tarran, BR Grubb, CA Van Heusden, S Okada, ... Journal of Biological Chemistry 279 (35), 36855-36864, 2004 | 268 | 2004 |
Regulation of airway surface liquid volume and mucus transport by active ion transport R Tarran Proceedings of the American Thoracic Society 1 (1), 42-46, 2004 | 267 | 2004 |
Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia R Tarran, L Trout, SH Donaldson, RC Boucher The Journal of general physiology 127 (5), 591-604, 2006 | 256 | 2006 |
Osmotic water permeabilities of cultured, well-differentiated normal and cystic fibrosis airway epithelia H Matsui, CW Davis, R Tarran, RC Boucher The Journal of clinical investigation 105 (10), 1419-1427, 2000 | 232 | 2000 |
Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells P Huang, ER Lazarowski, R Tarran, SL Milgram, RC Boucher, MJ Stutts Proceedings of the National Academy of Sciences 98 (24), 14120-14125, 2001 | 231 | 2001 |
Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways AL Garland, WG Walton, RD Coakley, CD Tan, RC Gilmore, CA Hobbs, ... Proceedings of the national academy of sciences 110 (40), 15973-15978, 2013 | 224 | 2013 |
Evaluation of e-liquid toxicity using an open-source high-throughput screening assay MF Sassano, ES Davis, JE Keating, BT Zorn, TK Kochar, MC Wolfgang, ... PLoS biology 16 (3), e2003904, 2018 | 203 | 2018 |
SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage A Garcia-Caballero, JE Rasmussen, E Gaillard, MJ Watson, JC Olsen, ... Proceedings of the national academy of sciences 106 (27), 11412-11417, 2009 | 199 | 2009 |
Chronic e-cigarette use increases neutrophil elastase and matrix metalloprotease levels in the lung A Ghosh, RD Coakley, AJ Ghio, MS Muhlebach, CR Esther Jr, NE Alexis, ... American journal of respiratory and critical care medicine 200 (11), 1392-1401, 2019 | 190 | 2019 |
Regulation of Murine Airway Surface Liquid Volume by CFTR and Ca2+-activated Cl− Conductances R Tarran, ME Loewen, AM Paradiso, JC Olsen, MA Gray, BE Argent, ... The Journal of general physiology 120 (3), 407-418, 2002 | 169 | 2002 |