| Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist T Luk, W Jin, A Zvonok, D Lu, XZ Lin, C Chavkin, A Makriyannis, K Mackie British journal of pharmacology 142 (3), 495, 2004 | 133 | 2004 |
| Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity AD Khanolkar, D Lu, M Ibrahim, RI Duclos, Jr, GA Thakur, TP Malan, Jr, ... Journal of medicinal chemistry 50 (26), 6493-6500, 2007 | 114 | 2007 |
| Molecular mechanism and cannabinoid pharmacology LD Schurman, D Lu, DA Kendall, AC Howlett, AH Lichtman Substance use disorders: from etiology to treatment, 323-353, 2020 | 101 | 2020 |
| Adamantyl cannabinoids: a novel class of cannabinergic ligands D Lu, Z Meng, GA Thakur, P Fan, J Steed, CL Tartal, DP Hurst, PH Reggio, ... Journal of medicinal chemistry 48 (14), 4576-4585, 2005 | 95 | 2005 |
| Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1) L Khurana, HI Ali, T Olszewska, KH Ahn, A Damaraju, DA Kendall, D Lu Journal of medicinal chemistry 57 (7), 3040-3052, 2014 | 62 | 2014 |
| Structure–Activity Relationship Study of Indole-2-carboxamides Identifies a Potent Allosteric Modulator for the Cannabinoid Receptor 1 (CB1) MM Mahmoud, HI Ali, KH Ahn, A Damaraju, S Samala, VK Pulipati, ... Journal of medicinal chemistry 56 (20), 7965-7975, 2013 | 50 | 2013 |
| Translational potential of allosteric modulators targeting the cannabinoid CB1 receptor D Lu, SS Immadi, Z Wu, DA Kendall Acta Pharmacologica Sinica 40 (3), 324-335, 2019 | 49 | 2019 |
| Pyrimidinyl Biphenylureas: Identification of New Lead Compounds as Allosteric Modulators of the Cannabinoid Receptor CB1 L Khurana, BQ Fu, AL Duddupudi, YH Liao, SS Immadi, DA Kendall, D Lu Journal of medicinal chemistry 60 (3), 1089-1104, 2017 | 47 | 2017 |
| Recent advances in the discovery of small-molecule inhibitors of HIV-1 integrase E Choi, JR Mallareddy, D Lu, S Kolluru Future science OA 4 (9), FSO338, 2018 | 45 | 2018 |
| Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity R Dopart, D Lu, AH Lichtman, DA Kendall Drug metabolism reviews 50 (1), 3-13, 2018 | 45 | 2018 |
| Behavioral effects of the novel cannabinoid full agonist AM 411 PJ McLaughlin, D Lu, KM Winston, G Thakur, LA Swezey, A Makriyannis, ... Pharmacology Biochemistry and Behavior 81 (1), 78-88, 2005 | 44 | 2005 |
| Novel conformationally restricted tetracyclic analogs of Δ8-tetrahydrocannabinol AD Khanolkar, D Lu, P Fan, X Tian, A Makriyannis Bioorganic & medicinal chemistry letters 9 (15), 2119-2124, 1999 | 44 | 1999 |
| Profiling two indole‐2‐carboxamides for allosteric modulation of the CB 1 receptor KH Ahn, MM Mahmoud, S Samala, D Lu, DA Kendall Journal of neurochemistry 124 (5), 584-589, 2013 | 41 | 2013 |
| Bornyl- and Isobornyl-Δ8-tetrahydrocannabinols: A Novel Class of Cannabinergic Ligands D Lu, J Guo, RI Duclos Jr, AL Bowman, A Makriyannis Journal of medicinal chemistry 51 (20), 6393-6399, 2008 | 41 | 2008 |
| SN-38-Cyclodextrin Complexation and Its Influence on the Solubility, Stability, and In Vitro Anticancer Activity Against Ovarian Cancer KK Vangara, HI Ali, D Lu, JL Liu, S Kolluru, S Palakurthi Aaps Pharmscitech 15, 472-482, 2014 | 39 | 2014 |
| The cannabinergic system as a target for anti-inflammatory therapies D Lu, V Kiran Vemuri, RI Duclos, A Makriyannis Current topics in medicinal chemistry 6 (13), 1401-1426, 2006 | 39 | 2006 |
| Cannabinoids selective for the CB2 receptor A Makriyannis, A Khanolkar, D Lu US Patent 6,166,066, 2000 | 36 | 2000 |
| Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes D Lu, R Dopart, DA Kendall Cell Stress and Chaperones 21 (1), 1-7, 2016 | 31 | 2016 |
| Novel biphenyl and biphenyl-like cannabinoids A Makriyannis, XZ Lai, D Lu US Patent App. 10/647,550, 2004 | 31 | 2004 |
| Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor CJ Qiao, HI Ali, KH Ahn, S Kolluru, DA Kendall, D Lu European journal of medicinal chemistry 121, 517-529, 2016 | 28 | 2016 |