Recent advances in the inhibition of p38 MAPK as a potential strategy for the treatment of Alzheimer’s disease JK Lee, NJ Kim Molecules 22 (8), 1287, 2017 | 297 | 2017 |
Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis DJ Chang, H An, K Kim, HH Kim, J Jung, JM Lee, NJ Kim, YT Han, H Yun, ... Journal of medicinal chemistry 55 (24), 10863-10884, 2012 | 102 | 2012 |
A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse MS Gee, SH Son, SH Jeon, J Do, N Kim, YJ Ju, SJ Lee, EK Chung, KS Inn, ... Alzheimer's Research & Therapy 12 (1), 1-18, 2020 | 90 | 2020 |
Targeted delivery of LXR agonist using a site-specific antibody–drug conjugate RKV Lim, S Yu, B Cheng, S Li, NJ Kim, Y Cao, V Chi, JY Kim, ... Bioconjugate chemistry 26 (11), 2216-2222, 2015 | 81 | 2015 |
Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock SK Chun, J Jang, S Chung, H Yun, NJ Kim, JW Jung, GH Son, YG Suh, ... ACS chemical biology 9 (3), 703-710, 2014 | 78 | 2014 |
Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors YT Han, GI Choi, D Son, NJ Kim, H Yun, S Lee, DJ Chang, HS Hong, ... Journal of medicinal chemistry 55 (21), 9120-9135, 2012 | 74 | 2012 |
Recent advances in the synthesis of biologically active cinnoline, phthalazine and quinoxaline derivatives Y Taek Han, JW Jung, NJ Kim Current Organic Chemistry 21 (14), 1265-1291, 2017 | 72 | 2017 |
Inhibition of respiratory syncytial virus replication and virus-induced p38 kinase activity by berberine HB Shin, MS Choi, CM Yi, J Lee, NJ Kim, KS Inn International immunopharmacology 27 (1), 65-68, 2015 | 54 | 2015 |
Development of small‐molecule Cryptochrome stabilizer derivatives as modulators of the circadian clock JW Lee, T Hirota, A Kumar, NJ Kim, S Irle, SA Kay ChemMedChem 10 (9), 1489-1497, 2015 | 53 | 2015 |
A novel p38 mitogen activated protein kinase (MAPK) specific inhibitor suppresses respiratory syncytial virus and influenza A virus replication by inhibiting virus-induced p38 … MS Choi, J Heo, CM Yi, J Ban, NJ Lee, NR Lee, SW Kim, NJ Kim, KS Inn Biochemical and Biophysical Research Communications 477 (3), 311-316, 2016 | 50 | 2016 |
Enantioselective total synthesis of a natural iridoid S Lee, SM Paek, H Yun, NJ Kim, YG Suh Organic Letters 13 (13), 3344-3347, 2011 | 47 | 2011 |
Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors YH Lee, MC Shin, YD Yun, SY Shin, JM Kim, JM Seo, NJ Kim, JH Ryu, ... Bioorganic & medicinal chemistry 23 (1), 231-240, 2015 | 45 | 2015 |
Fulgidic acid isolated from the rhizomes of Cyperus rotundus suppresses LPS-induced iNOS, COX-2, TNF-α, and IL-6 expression by AP-1 inactivation in RAW264. 7 macrophages JS Shin, Y Hong, HH Lee, B Ryu, YW Cho, NJ Kim, DS Jang, KT Lee Biological and Pharmaceutical Bulletin 38 (7), 1081-1086, 2015 | 44 | 2015 |
Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice V Agrawal, S Maharjan, K Kim, NJ Kim, J Son, K Lee, HJ Choi, SS Rho, ... Oncotarget 5 (9), 2761, 2014 | 44 | 2014 |
A Concise Total Synthesis of (+)‐Tetrabenazine and (+)‐α‐Dihydrotetrabenazine SM Paek, NJ Kim, D Shin, JK Jung, JW Jung, DJ Chang, H Moon, YG Suh Chemistry–A European Journal 16 (15), 4623-4628, 2010 | 43 | 2010 |
Sac-1004, a novel vascular leakage blocker, enhances endothelial barrier through the cAMP/Rac/cortactin pathway S Maharjan, K Kim, V Agrawal, HJ Choi, NJ Kim, YM Kim, YG Suh, ... Biochemical and biophysical research communications 435 (3), 420-427, 2013 | 38 | 2013 |
A versatile approach to flavones via a one-pot Pd (II)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones J Lee, J Yu, SH Son, J Heo, T Kim, JY An, KS Inn, NJ Kim Organic & Biomolecular Chemistry 14 (2), 777-784, 2016 | 37 | 2016 |
Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKKβ/NF-κB signaling in mice JM Cho, SM Yun, YH Choi, J Heo, NJ Kim, SH Kim, EH Kim Oncotarget 9 (1), 866, 2017 | 36 | 2017 |
Design, Synthesis, and Biological Evaluation of Novel Constrained meta-Substituted Phenyl Propanoic Acids as Peroxisome Proliferator-Activated Receptor α and … YG Suh, NJ Kim, BW Koo, KO Lee, SH Moon, DH Shin, JW Jung, ... Journal of medicinal chemistry 51 (20), 6318-6333, 2008 | 36 | 2008 |
Multidrug Resistance-Associated Protein 1 Mediates 15-Deoxy-Δ12,14-prostaglandin J2-Induced Expression of Glutamate Cysteine Ligase Expression via Nrf2 … NY Song, DH Kim, EH Kim, HK Na, NJ Kim, YG Suh, YJ Surh Chemical research in toxicology 24 (8), 1231-1241, 2011 | 35 | 2011 |