The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent RM Mancina, P Dongiovanni, S Petta, P Pingitore, M Meroni, R Rametta, ... Gastroenterology 150 (5), 1219-1230. e6, 2016 | 691 | 2016 |
Statin use and non-alcoholic steatohepatitis in at risk individuals P Dongiovanni, S Petta, V Mannisto, RM Mancina, R Pipitone, V Karja, ... Journal of hepatology 63 (3), 705-712, 2015 | 470 | 2015 |
An integrated understanding of the rapid metabolic benefits of a carbohydrate-restricted diet on hepatic steatosis in humans A Mardinoglu, H Wu, E Bjornson, C Zhang, A Hakkarainen, SM Räsänen, ... Cell metabolism 27 (3), 559-571. e5, 2018 | 446 | 2018 |
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells C Pirazzi, L Valenti, BM Motta, P Pingitore, K Hedfalk, RM Mancina, ... Human molecular genetics 23 (15), 4077-4085, 2014 | 416 | 2014 |
Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver P Dongiovanni, S Stender, A Pietrelli, RM Mancina, A Cespiati, S Petta, ... Journal of internal medicine 283 (4), 356-370, 2018 | 354 | 2018 |
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro C Pirazzi, M Adiels, MA Burza, RM Mancina, M Levin, M Ståhlman, ... Journal of hepatology 57 (6), 1276-1282, 2012 | 339 | 2012 |
PNPLA3 I148M polymorphism and progressive liver disease P Dongiovanni, B Donati, R Fares, R Lombardi, RM Mancina, S Romeo, ... World journal of gastroenterology: WJG 19 (41), 6969, 2013 | 294 | 2013 |
MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals B Donati, P Dongiovanni, S Romeo, M Meroni, M McCain, L Miele, S Petta, ... Scientific reports 7 (1), 4492, 2017 | 277 | 2017 |
Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function P Pingitore, C Pirazzi, RM Mancina, BM Motta, C Indiveri, A Pujia, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 247 | 2014 |
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice D Lindén, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andréasson, ... Molecular metabolism 22, 49-61, 2019 | 217 | 2019 |
PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis P Pingitore, P Dongiovanni, BM Motta, M Meroni, SM Lepore, ... Human molecular genetics 25 (23), 5212-5222, 2016 | 141 | 2016 |
Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity MR Taskinen, S Söderlund, LH Bogl, A Hakkarainen, N Matikainen, ... Journal of internal medicine 282 (2), 187-201, 2017 | 140 | 2017 |
The rs2294918 E434K variant modulates patatin‐like phospholipase domain‐containing 3 expression and liver damage B Donati, BM Motta, P Pingitore, M Meroni, A Pietrelli, A Alisi, S Petta, ... Hepatology 63 (3), 787-798, 2016 | 137 | 2016 |
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals MA Burza, C Pirazzi, C Maglio, K Sjöholm, RM Mancina, PA Svensson, ... Digestive and Liver Disease 44 (12), 1037-1041, 2012 | 130 | 2012 |
Exome-wide association study on alanine aminotransferase identifies sequence variants in the GPAM and APOE associated with fatty liver disease O Jamialahmadi, RM Mancina, E Ciociola, F Tavaglione, PK Luukkonen, ... Gastroenterology 160 (5), 1634-1646. e7, 2021 | 120 | 2021 |
PNPLA3 I148M variant influences circulating retinol in adults with nonalcoholic fatty liver disease or obesity A Mondul, RM Mancina, A Merlo, P Dongiovanni, R Rametta, T Montalcini, ... The Journal of nutrition 145 (8), 1687-1691, 2015 | 120 | 2015 |
LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover Y Tanaka, Y Shimanaka, A Caddeo, T Kubo, Y Mao, T Kubota, N Kubota, ... Gut 70 (1), 180-193, 2021 | 118 | 2021 |
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids S Prill, A Caddeo, G Baselli, O Jamialahmadi, P Dongiovanni, R Rametta, ... Scientific reports 9 (1), 11585, 2019 | 113 | 2019 |
Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease O Govaere, SK Petersen, N Martinez-Lopez, J Wouters, M Van Haele, ... Journal of hepatology 76 (5), 1001-1012, 2022 | 110 | 2022 |
Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker GA Baselli, P Dongiovanni, R Rametta, M Meroni, S Pelusi, M Maggioni, ... Gut 69 (10), 1855-1866, 2020 | 99 | 2020 |