| Structure of a human common cold virus and functional relationship to other picornaviruses. MG Rossmann, E Arnold, JW Erickson, EA Frankenberger, JP Griffith, ... Nature 317 (6033), 145, 1985 | 1856 | 1985 |
| Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA A Jacobo-Molina, J Ding, RG Nanni, AD Clark, X Lu, C Tantillo, ... Proceedings of the National Academy of Sciences 90 (13), 6320, 1993 | 1530 | 1993 |
| Isolation and structure of bryostatin 1 GR Pettit, CL Herald, DL Doubek, DL Herald, E Arnold, J Clardy Journal of the American Chemical Society 104 (24), 6846-6848, 1982 | 1019 | 1982 |
| International tables for crystallography T Hahn, H Wondratschek, U Müller, U Shmueli, E Prince, A Authier, ... John Wiley & Sons, Incorporated, 2017 | 802* | 2017 |
| Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition SG Sarafianos, B Marchand, K Das, DM Himmel, MA Parniak, SH Hughes, ... Journal of molecular biology 385 (3), 693-713, 2009 | 744 | 2009 |
| Locations of Anti-AIDS Drug Binding Sites and Resistance Mutations in the Three-dimensional Structure of HIV-1 Reverse Transcriptase:: Implications for Mechanisms of Drug … C Tantillo, J Ding, A Jacobo-Molina, RG Nanni, PL Boyer, SH Hughes, ... Journal of molecular biology 243 (3), 369-387, 1994 | 711 | 1994 |
| Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that … K Das, AD Clark, PJ Lewi, J Heeres, MR De Jonge, LMH Koymans, ... Journal of medicinal chemistry 47 (10), 2550-2560, 2004 | 658 | 2004 |
| The site of attachment in human rhinovirus 14 for antiviral agents that inhibit uncoating TJ Smith, MJ Kremer, M Luo, G Vriend, E Arnold, G Kamer, MG Rossmann, ... Science 233 (4770), 1286, 1986 | 600 | 1986 |
| Castanospermine, a 1, 6, 7, 8-tetrahydroxyoctahydroindolizine alkaloid, from seeds of Castanospermum australe LD Hohenschutz, EA Bell, PJ Jewess, DP Leworthy, RJ Pryce, E Arnold, ... Phytochemistry 20 (4), 811-814, 1981 | 550 | 1981 |
| Crystal structure of HIV‐1 reverse transcriptase in complex with a polypurine tract RNA: DNA SG Sarafianos, K Das, C Tantillo, AD ClarkJr, J Ding, JM Whitcomb, ... The EMBO journal, 2001 | 548 | 2001 |
| Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity X Xu, J Zhao, Z Xu, B Peng, Q Huang, E Arnold, J Ding Journal of Biological Chemistry 279 (32), 33946-33957, 2004 | 506 | 2004 |
| Structures of influenza A proteins and insights into antiviral drug targets K Das, JM Aramini, LC Ma, RM Krug, E Arnold Nature structural & molecular biology 17 (5), 530-538, 2010 | 497 | 2010 |
| Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides T Shirasaka, MF Kavlick, T Ueno, WY Gao, E Kojima, ML Alcaide, ... Proceedings of the National Academy of Sciences 92 (6), 2398, 1995 | 492 | 1995 |
| Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors J Ding, K Das, H Moereels, L Koymans, K Andries, PAJ Janssen, ... Nature structural biology 2 (5), 407-415, 1995 | 457 | 1995 |
| In Search of a Novel Anti-HIV Drug: Multidisciplinary Coordination in the Discovery of 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl … PAJ Janssen, PJ Lewi, E Arnold, F Daeyaert, M De Jonge, J Heeres, ... Journal of medicinal chemistry 48 (6), 1901-1909, 2005 | 433 | 2005 |
| The atomic structure of Mengo virus at 3.0 A resolution M Luo, G Vriend, G Kamer, I Minor, E Arnold, MG Rossmann, U Boege, ... Science 235 (4785), 182, 1987 | 433 | 1987 |
| Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2 … J Ding, K Das, Y Hsiou, SG Sarafianos, AD Clark, A Jacobo-Molina, ... Journal of molecular biology 284 (4), 1095-1111, 1998 | 430 | 1998 |
| High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations K Das, JD Bauman, AD Clark Jr, YV Frenkel, PJ Lewi, AJ Shatkin, ... Proceedings of the National Academy of Sciences 105 (5), 1466-1471, 2008 | 415 | 2008 |
| Structure of unliganded HIV-1 reverse transcriptase at 2.7 Å resolution: implications of conformational changes for polymerization and inhibition mechanisms Y Hsiou, J Ding, K Das, AD Clark Jr, SH Hughes, E Arnold Structure 4 (7), 853-860, 1996 | 405 | 1996 |
| Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids SG Sarafianos, K Das, AD Clark, J Ding, PL Boyer, SH Hughes, E Arnold Proceedings of the National Academy of Sciences 96 (18), 10027, 1999 | 396 | 1999 |
Kalyan DasCanada Excellence Research Chair & Professor, U. Alberta, Canada; Professor, KU Leuven, BelgiumOverená e-mailová adresa na: kuleuven.be
