The nuclear receptor superfamily: the second decade DJ Mangelsdorf, C Thummel, M Beato, P Herrlich, G Schütz, K Umesono, ... Cell 83 (6), 835-839, 1995 | 9049 | 1995 |
The RXR heterodimers and orphan receptors DJ Mangelsdorf, RM Evans Cell 83 (6), 841-850, 1995 | 4139 | 1995 |
Identification of a nuclear receptor for bile acids M Makishima, AY Okamoto, JJ Repa, H Tu, RM Learned, A Luk, MV Hull, ... Science 284 (5418), 1362-1365, 1999 | 3158 | 1999 |
Nuclear receptors and lipid physiology: opening the X-files A Chawla, JJ Repa, RM Evans, DJ Mangelsdorf Science 294 (5548), 1866-1870, 2001 | 2664 | 2001 |
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor RA Heyman, DJ Mangelsdorf, JA Dyck, RB Stein, G Eichele, RM Evans, ... Cell 68 (2), 397-406, 1992 | 2222 | 1992 |
An oxysterol signalling pathway mediated by the nuclear receptor LXRα BA Janowski, PJ Willy, TR Devi, JR Falck, DJ Mangelsdorf Nature 383 (6602), 728-731, 1996 | 2173 | 1996 |
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ JJ Repa, G Liang, J Ou, Y Bashmakov, JMA Lobaccaro, I Shimomura, ... Genes & development 14 (22), 2819-2830, 2000 | 2076 | 2000 |
Role of LXRs in control of lipogenesis JR Schultz, H Tu, A Luk, JJ Repa, JC Medina, L Li, S Schwendner, ... Genes & development 14 (22), 2831-2838, 2000 | 2056 | 2000 |
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis T Inagaki, M Choi, A Moschetta, LI Peng, CL Cummins, JG McDonald, ... Cell metabolism 2 (4), 217-225, 2005 | 2046 | 2005 |
Nuclear receptor that identifies a novel retinoic acid response pathway DJ Mangelsdorf, ES Ong, JA Dyck, RM Evans Nature 345 (6272), 224-229, 1990 | 1947 | 1990 |
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα DJ Peet, SD Turley, W Ma, BA Janowski, JMA Lobaccaro, RE Hammer, ... Cell 93 (5), 693-704, 1998 | 1839 | 1998 |
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. SA Kliewer, BM Forman, B Blumberg, ES Ong, U Borgmeyer, ... Proceedings of the National Academy of Sciences 91 (15), 7355-7359, 1994 | 1838 | 1994 |
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling SA Kliewer, K Umesono, DJ Mangelsdorf, RM Evans Nature 355 (6359), 446-449, 1992 | 1793 | 1992 |
Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21 T Inagaki, P Dutchak, G Zhao, X Ding, L Gautron, V Parameswara, Y Li, ... Cell metabolism 5 (6), 415-425, 2007 | 1772 | 2007 |
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors TT Lu, M Makishima, JJ Repa, K Schoonjans, TA Kerr, J Auwerx, ... Molecular cell 6 (3), 507-515, 2000 | 1740 | 2000 |
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers JJ Repa, SD Turley, JMA Lobaccaro, J Medina, L Li, K Lustig, B Shan, ... Science 289 (5484), 1524-1529, 2000 | 1660 | 2000 |
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. DJ Mangelsdorf, U Borgmeyer, RA Heyman, JY Zhou, ES Ong, AE Oro, ... Genes & development 6 (3), 329-344, 1992 | 1558 | 1992 |
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c M Watanabe, SM Houten, L Wang, A Moschetta, DJ Mangelsdorf, ... The Journal of clinical investigation 113 (10), 1408-1418, 2004 | 1541 | 2004 |
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors SB Joseph, A Castrillo, BA Laffitte, DJ Mangelsdorf, P Tontonoz Nature medicine 9 (2), 213-219, 2003 | 1496 | 2003 |
LXR, a nuclear receptor that defines a distinct retinoid response pathway. PJ Willy, K Umesono, ES Ong, RM Evans, RA Heyman, DJ Mangelsdorf Genes & development 9 (9), 1033-1045, 1995 | 1446 | 1995 |