Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel C Bouzat, F Gumilar, G Spitzmaul, HL Wang, D Rayes, SB Hansen, ... Nature 430 (7002), 896, 2004 | 342 | 2004 |
Mutation of the acetylcholine receptor α subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity SM Sine, K Ohno, C Bouzat, A Auerbach, M Milone, JN Pruitt, AG Engel Neuron 15 (1), 229-239, 1995 | 322 | 1995 |
Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit K Ohno, DO Hutchinson, M Milone, JM Brengman, C Bouzat, SM Sine, ... Proceedings of the National Academy of Sciences 92 (3), 758-762, 1995 | 310 | 1995 |
New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome AG Engel, K Ohno, M Milone, HL Wang, S Nakano, C Bouzat, JN Pruitt, ... Human molecular genetics 5 (9), 1217-1227, 1996 | 255 | 1996 |
Understanding the bases of function and modulation of α7 nicotinic receptors: implications for drug discovery J Corradi, C Bouzat Molecular pharmacology 90 (3), 288-299, 2016 | 219 | 2016 |
End‐plate acetylcholine receptor deficiency due to nonsense mutations in the ε subunit AG Engel, K Ohno, C Bouzat, SM Sine, RC Griggs Annals of neurology 40 (5), 810-817, 1996 | 195 | 1996 |
Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors C Bouzat, N Bren, SM Sine Neuron 13 (6), 1395-1402, 1994 | 184 | 1994 |
Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors HR Arias, P Bhumireddy, C Bouzat The international journal of biochemistry & cell biology 38 (8), 1254-1276, 2006 | 165 | 2006 |
Number and locations of agonist binding sites required to activate homomeric Cys-loop receptors D Rayes, MJ De Rosa, SM Sine, C Bouzat Journal of Neuroscience 29 (18), 6022-6032, 2009 | 140 | 2009 |
The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization C Bouzat, M Bartos, J Corradi, SM Sine Journal of Neuroscience 28 (31), 7808-7819, 2008 | 135 | 2008 |
Stoichiometry of the α9α10 nicotinic cholinergic receptor PV Plazas, E Katz, ME Gomez-Casati, C Bouzat, AB Elgoyhen Journal of Neuroscience 25 (47), 10905-10912, 2005 | 134 | 2005 |
An intrinsic GABAergic system in human lymphocytes L Dionisio, MJ De Rosa, C Bouzat, M del Carmen Esandi Neuropharmacology 60 (2-3), 513-519, 2011 | 131 | 2011 |
Modulation of Muscle Nicotinic Acetylcholine Receptors by the Glucocorticoid Hydrocortisone POSSIBLE ALLOSTERIC MECHANISM OF CHANNEL BLOCKADE C Bouzat, FJ Barrantes Journal of Biological Chemistry 271 (42), 25835-25841, 1996 | 115 | 1996 |
Nicotinic receptor fourth transmembrane domain: hydrogen bonding by conserved threonine contributes to channel gating kinetics C Bouzat, F Barrantes, S Sine The Journal of general physiology 115 (5), 663-672, 2000 | 108 | 2000 |
Relationship between α7 nAChR and apoptosis in human lymphocytes MJ De Rosa, M del Carmen Esandi, A Garelli, D Rayes, C Bouzat Journal of neuroimmunology 160 (1), 154-161, 2005 | 106 | 2005 |
Mutations at lipid-exposed residues of the acetylcholine receptor affect its gating kinetics C Bouzat, AM Roccamo, I Garbus, FJ Barrantes Molecular Pharmacology 54 (1), 146-153, 1998 | 103 | 1998 |
Molecular function of α7 nicotinic receptors as drug targets C Bouzat, M Lasala, BE Nielsen, J Corradi, MC Esandi The Journal of physiology, 2017 | 102 | 2017 |
Stoichiometry for activation of neuronal α7 nicotinic receptors N Andersen, J Corradi, SM Sine, C Bouzat Proceedings of the National Academy of Sciences 110 (51), 20819-20824, 2013 | 101 | 2013 |
Single-channel and structural foundations of neuronal α7 acetylcholine receptor potentiation JB Corrie, CR Free, J Corradi, C Bouzat, SM Sine Journal of Neuroscience 31 (39), 13870-13879, 2011 | 82 | 2011 |
Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic antidepressants F Gumilar, HR Arias, G Spitzmaul, C Bouzat Neuropharmacology 45 (7), 964-976, 2003 | 81 | 2003 |