The expanding universe of T-cell subsets: Th1, Th2 and more TR Mosmann, S Sad Immunology today 17 (3), 138-146, 1996 | 5487 | 1996 |
Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines S Sad, R Marcotte, TR Mosmann Immunity 2 (3), 271-279, 1995 | 921 | 1995 |
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis F Winau, S Weber, S Sad, J De Diego, SL Hoops, B Breiden, K Sandhoff, ... Immunity 24 (1), 105-117, 2006 | 525 | 2006 |
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium N Robinson, S McComb, R Mulligan, R Dudani, L Krishnan, S Sad Nature immunology 13 (10), 954-962, 2012 | 490 | 2012 |
Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. S Sad, TR Mosmann Journal of immunology (Baltimore, Md.: 1950) 153 (8), 3514-3522, 1994 | 375 | 1994 |
Functions of CD8 T-cell subsets secreting different cytokine patterns TR Mosmann, L Li, S Sad Seminars in immunology 9 (2), 87-92, 1997 | 328 | 1997 |
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis D Karunakaran, M Geoffrion, L Wei, W Gan, L Richards, P Shangari, ... Science advances 2 (7), e1600224, 2016 | 276 | 2016 |
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages S McComb, E Cessford, NA Alturki, J Joseph, B Shutinoski, JB Startek, ... Proceedings of the National Academy of Sciences 111 (31), E3206-E3213, 2014 | 213 | 2014 |
cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation S McComb, HH Cheung, RG Korneluk, S Wang, L Krishnan, S Sad Cell Death & Differentiation 19 (11), 1791-1801, 2012 | 175 | 2012 |
CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions. L Li, S Sad, D Kägi, TR Mosmann Journal of immunology (Baltimore, Md.: 1950) 158 (9), 4152-4161, 1997 | 163 | 1997 |
IL-15 regulates CD8+ T cell contraction during primary infection T Yajima, K Yoshihara, K Nakazato, S Kumabe, S Koyasu, S Sad, H Shen, ... The Journal of Immunology 176 (1), 507-515, 2006 | 161 | 2006 |
Reducing the stimulation of CD8+ T cells during infection with intracellular bacteria promotes differentiation primarily into a central (CD62LhighCD44high) subset H van Faassen, M Saldanha, D Gilbertson, R Dudani, L Krishnan, S Sad The Journal of Immunology 174 (9), 5341-5350, 2005 | 136 | 2005 |
Multiple mechanisms compensate to enhance tumor-protective CD8+ T cell response in the long-term despite poor CD8+ T cell priming initially: comparison between an acute versus … R Dudani, Y Chapdelaine, H Faassen, DK Smith, H Shen, L Krishnan, ... The Journal of Immunology 168 (11), 5737-5745, 2002 | 136 | 2002 |
Biochemical engineering of surface α2–8 polysialic acid for immunotargeting tumor cells T Liu, Z Guo, Q Yang, S Sad, HJ Jennings Journal of Biological Chemistry 275 (42), 32832-32836, 2000 | 131 | 2000 |
Archaeosomes induce long-term CD8+ cytotoxic T cell response to entrapped soluble protein by the exogenous cytosolic pathway, in the absence of CD4+ T cell help L Krishnan, S Sad, GB Patel, GD Sprott The Journal of Immunology 165 (9), 5177-5185, 2000 | 128 | 2000 |
VEGF-mediated induction of PRD1-BF1/Blimp1 expression sensitizes tumor vasculature to oncolytic virus infection R Arulanandam, C Batenchuk, FA Angarita, K Ottolino-Perry, ... Cancer cell 28 (2), 210-224, 2015 | 121 | 2015 |
The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo L Krishnan, S Sad, GB Patel, GD Sprott The Journal of Immunology 166 (3), 1885-1893, 2001 | 117 | 2001 |
Interleukin (IL) 4, in the absence of antigen stimulation, induces an anergy-like state in differentiated CD8+ TC1 cells: loss of IL-2 synthesis and autonomous proliferation … S Sad, TR Mosmann The Journal of experimental medicine 182 (5), 1505-1515, 1995 | 108 | 1995 |
Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner B Shutinoski, M Hakimi, IE Harmsen, M Lunn, J Rocha, N Lengacher, ... Science translational medicine 11 (511), eaas9292, 2019 | 102 | 2019 |
Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation. S Sad, D Kägi, TR Mosmann The Journal of experimental medicine 184 (4), 1543-1547, 1996 | 101 | 1996 |