| Applications of machine learning in drug discovery and development J Vamathevan, D Clark, P Czodrowski, I Dunham, E Ferran, G Lee, B Li, ... Nature reviews Drug discovery 18 (6), 463-477, 2019 | 2540 | 2019 |
| Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE modENCODE Consortium, S Roy, J Ernst, PV Kharchenko, P Kheradpour, ... Science 330 (6012), 1787-1797, 2010 | 1113 | 2010 |
| Unlocking the secrets of the genome SE Celniker, LAL Dillon, MB Gerstein, KC Gunsalus, S Henikoff, ... Nature 459 (7249), 927-930, 2009 | 978 | 2009 |
| A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance D Chauhan, Z Tian, B Nicholson, KG Kumar, B Zhou, R Carrasco, ... Cancer Cell 22 (3), 345-358, 2012 | 604 | 2012 |
| A cis-regulatory map of the Drosophila genome N Nègre, CD Brown, L Ma, CA Bristow, SW Miller, U Wagner, ... Nature 471 (7339), 527-531, 2011 | 591 | 2011 |
| A Comprehensive Map of Insulator Elements for the Drosophila Genome N Nègre, CD Brown, PK Shah, P Kheradpour, CA Morrison, JG Henikoff, ... PLoS genetics 6 (1), e1000814, 2010 | 382 | 2010 |
| The SMARCA2/4 ATPase domain surpasses the bromodomain as a drug target in SWI/SNF-mutant cancers: insights from cDNA rescue and PFI-3 inhibitor studies B Vangamudi, TA Paul, PK Shah, M Kost-Alimova, L Nottebaum, X Shi, ... Cancer research 75 (18), 3865-3878, 2015 | 266 | 2015 |
| Information extraction from full text scientific articles: where are the keywords? PK Shah, C Perez-Iratxeta, P Bork, MA Andrade BMC bioinformatics 4, 1-9, 2003 | 262 | 2003 |
| Genomic analysis of estrogen cascade reveals histone variant H2A. Z associated with breast cancer progression S Hua, CB Kallen, R Dhar, MT Baquero, CE Mason, BA Russell, PK Shah, ... Molecular systems biology 4 (1), 188, 2008 | 225 | 2008 |
| Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial SP D'Angelo, S Bhatia, AS Brohl, O Hamid, JM Mehnert, P Terheyden, ... Journal for immunotherapy of cancer 8 (1), e000674, 2020 | 205 | 2020 |
| Computational characterization of multiple Gag-like human proteins M Campillos, T Doerks, PK Shah, P Bork Trends in Genetics 22 (11), 585-589, 2006 | 182 | 2006 |
| In vivo functional platform targeting patient-derived xenografts identifies WDR5-Myc association as a critical determinant of pancreatic cancer A Carugo, G Genovese, S Seth, L Nezi, JL Rose, D Bossi, A Cicalese, ... Cell reports 16 (1), 133-147, 2016 | 144 | 2016 |
| PASBio: predicate-argument structures for event extraction in molecular biology T Wattarujeekrit, PK Shah, N Collier BMC bioinformatics 5, 1-20, 2004 | 136 | 2004 |
| First-line avelumab in a cohort of 116 patients with metastatic Merkel cell carcinoma (JAVELIN Merkel 200): primary and biomarker analyses of a phase II study SP D'Angelo, C Lebbé, L Mortier, AS Brohl, N Fazio, JJ Grob, N Prinzi, ... Journal for immunotherapy of cancer 9 (7), e002646, 2021 | 131 | 2021 |
| HLA-A* 03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study V Naranbhai, M Viard, M Dean, S Groha, DA Braun, C Labaki, SA Shukla, ... The Lancet Oncology 23 (1), 172-184, 2022 | 90 | 2022 |
| Integrative analysis of gene and miRNA expression profiles with transcription factor–miRNA feed-forward loops identifies regulators in human cancers Z Yan, PK Shah, SB Amin, MK Samur, N Huang, X Wang, V Misra, H Ji, ... Nucleic acids research 40 (17), e135-e135, 2012 | 89 | 2012 |
| Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer P Pettazzoni, A Viale, P Shah, A Carugo, H Ying, H Wang, G Genovese, ... Cancer research 75 (6), 1091-1101, 2015 | 87 | 2015 |
| Gene expression profile alone is inadequate in predicting complete response in multiple myeloma SB Amin, WK Yip, S Minvielle, A Broyl, Y Li, B Hanlon, D Swanson, ... Leukemia 28 (11), 2229-2234, 2014 | 87 | 2014 |
| Determinants of antigenicity and specificity in immune response for protein sequences Y Wang, W Wu, NN Negre, KP White, C Li, PK Shah BMC bioinformatics 12, 1-13, 2011 | 86 | 2011 |
| TRIM28 and interacting KRAB-ZNFs control self-renewal of human pluripotent stem cells through epigenetic repression of pro-differentiation genes U Oleksiewicz, M Gładych, AT Raman, H Heyn, E Mereu, ... Stem cell reports 9 (6), 2065-2080, 2017 | 85 | 2017 |
Kevin P. WhiteNational University of SingaporeOverená e-mailová adresa na: nus.edu.sg
