| Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation A Chang, S Singh, GN Phillips Jr, JS Thorson Current opinion in biotechnology 22 (6), 800-808, 2011 | 186 | 2011 |
| Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress‐related protein S Singh, CC Cornilescu, RC Tyler, G Cornilescu, M Tonelli, MS Lee, ... Protein Science 14 (10), 2601-2609, 2005 | 152 | 2005 |
| Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S‐Adenosyl‐L‐Methionine Analogues S Singh, J Zhang, TD Huber, M Sunkara, K Hurley, RD Goff, G Wang, ... Angewandte Chemie International Edition 53 (15), 3965-3969, 2014 | 151 | 2014 |
| Auto-induction medium for the production of [U-15N]- and [U-13C, U-15N]-labeled proteins for NMR screening and structure determination RC Tyler, HK Sreenath, S Singh, DJ Aceti, CA Bingman, JL Markley, ... Protein expression and purification 40 (2), 268-278, 2005 | 132 | 2005 |
| The structural biology of enzymes involved in natural product glycosylation S Singh, GN Phillips Jr, JS Thorson Natural product reports 29 (10), 1201-1237, 2012 | 125 | 2012 |
| The structure of flavin‐dependent tryptophan 7‐halogenase RebH E Bitto, Y Huang, CA Bingman, S Singh, JS Thorson, GN Phillips Proteins: Structure, Function, and Bioinformatics 70 (1), 289-293, 2008 | 117 | 2008 |
| Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis RW Gantt, P Peltier-Pain, S Singh, M Zhou, JS Thorson Proceedings of the National Academy of Sciences 110 (19), 7648-7653, 2013 | 99 | 2013 |
| Structure and mechanism of the rebeccamycin sugar 4′-O-methyltransferase RebM S Singh, JG McCoy, C Zhang, CA Bingman, GN Phillips, JS Thorson Journal of Biological Chemistry 283 (33), 22628-22636, 2008 | 76 | 2008 |
| Comparison of cell‐based and cell‐free protocols for producing target proteins from the Arabidopsis thaliana genome for structural studies RC Tyler, DJ Aceti, CA Bingman, CC Cornilescu, BG Fox, RO Frederick, ... Proteins: Structure, Function, and Bioinformatics 59 (3), 633-643, 2005 | 74 | 2005 |
| Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis C Zhang, E Bitto, RD Goff, S Singh, CA Bingman, BR Griffith, C Albermann, ... Chemistry & biology 15 (8), 842-853, 2008 | 63 | 2008 |
| Structure and specificity of a permissive bacterial C-prenyltransferase SI Elshahawi, H Cao, KA Shaaban, LV Ponomareva, T Subramanian, ... Nature chemical biology 13 (4), 366-368, 2017 | 62 | 2017 |
| Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity A Chang, S Singh, KE Helmich, RD Goff, CA Bingman, JS Thorson, ... Proceedings of the National Academy of Sciences 108 (43), 17649-17654, 2011 | 59 | 2011 |
| Solution structure and DNA‐binding properties of the C‐terminal domain of UvrC from E.coli S Singh, GE Folkers, A Bonvin, R Boelens, R Wechselberger, A Niztayev, ... The EMBO journal 21 (22), 6257-6266, 2002 | 58 | 2002 |
| Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus F Wang, S Singh, J Zhang, TD Huber, KE Helmich, M Sunkara, KA Hurley, ... The FEBS journal 281 (18), 4224-4239, 2014 | 51 | 2014 |
| Functional AdoMet isosteres resistant to classical AdoMet degradation pathways TD Huber, F Wang, S Singh, BR Johnson, J Zhang, M Sunkara, ... ACS chemical biology 11 (9), 2484-2491, 2016 | 48 | 2016 |
| Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2 KA Shaaban, S Singh, SI Elshahawi, X Wang, LV Ponomareva, ... The Journal of antibiotics 67 (3), 223-230, 2014 | 41 | 2014 |
| Structural characterization of the mitomycin 7‐O‐methyltransferase S Singh, A Chang, RD Goff, CA Bingman, S Grüschow, DH Sherman, ... Proteins: Structure, Function, and Bioinformatics 79 (7), 2181-2188, 2011 | 36 | 2011 |
| Structural insight into the self-sacrifice mechanism of enediyne resistance S Singh, MH Hager, C Zhang, BR Griffith, MS Lee, K Hallenga, JL Markley, ... ACS chemical biology 1 (7), 451-460, 2006 | 32 | 2006 |
| Chemoenzymatic synthesis of daptomycin analogs active against daptomycin-resistant strains EM Scull, C Bandari, BP Johnson, ED Gardner, M Tonelli, J You, ... Applied Microbiology and Biotechnology 104, 7853-7865, 2020 | 31 | 2020 |
| Structural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway JG McCoy, HD Johnson, S Singh, CA Bingman, IK Lei, JS Thorson, ... Proteins: Structure, Function, and Bioinformatics 74 (1), 50-60, 2009 | 31 | 2009 |
Jon S. ThorsonProfessor and Associate Dean for Research, University of Kentucky College of PharmacyOverená e-mailová adresa na: uky.edu
