| Adapting to obesity with adipose tissue inflammation SM Reilly, AR Saltiel Nature Reviews Endocrinology 13 (11), 633-643, 2017 | 1306 | 2017 |
| Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarization and insulin sensitivity K Kang, SM Reilly, V Karabacak, MR Gangl, K Fitzgerald, B Hatano, ... Cell metabolism 7 (6), 485-495, 2008 | 853 | 2008 |
| Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ... Nature medicine 21 (2), 159-165, 2015 | 798 | 2015 |
| An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice SM Reilly, SH Chiang, SJ Decker, L Chang, M Uhm, MJ Larsen, JR Rubin, ... Nature medicine 19 (3), 313-321, 2013 | 472 | 2013 |
| TBK1 at the crossroads of inflammation and energy homeostasis in adipose tissue P Zhao, X Sun, SM Reilly, M Uhm, Z Liao, Y Skorobogatko, AR Saltiel Cell 172 (4), 731-743. e12, 2018 | 250 | 2018 |
| PPARδ as a therapeutic target in metabolic disease SM Reilly, CH Lee FEBS letters 582 (1), 26-31, 2008 | 208 | 2008 |
| Role of peroxisome proliferator-activated receptor δ/β in hepatic metabolic regulation S Liu, B Hatano, M Zhao, CC Yen, K Kang, SM Reilly, MR Gangl, ... Journal of Biological Chemistry 286 (2), 1237-1247, 2011 | 177 | 2011 |
| Inhibition of IKKɛ and TBK1 improves glucose control in a subset of patients with type 2 diabetes EA Oral, SM Reilly, AV Gomez, R Meral, L Butz, N Ajluni, TL Chenevert, ... Cell metabolism 26 (1), 157-170. e7, 2017 | 168 | 2017 |
| Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1 J Mowers, M Uhm, SM Reilly, J Simon, D Leto, SH Chiang, L Chang, ... Elife 2, e01119, 2013 | 159 | 2013 |
| A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis SM Reilly, M Ahmadian, BF Zamarron, L Chang, M Uhm, BA Poirier, ... Nature communications 6 (1), 6047, 2015 | 106 | 2015 |
| Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1–mediated p62/sequestosome 1 phosphorylation CS Cho, HW Park, A Ho, IA Semple, B Kim, I Jang, H Park, S Reilly, ... Hepatology 68 (4), 1331-1346, 2018 | 99 | 2018 |
| TANK-binding kinase 1 regulates the localization of acyl-CoA synthetase ACSL1 to control hepatic fatty acid oxidation JY Huh, SM Reilly, M Abu-Odeh, AN Murphy, SK Mahata, J Zhang, Y Cho, ... Cell metabolism 32 (6), 1012-1027. e7, 2020 | 94 | 2020 |
| FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes M Abu-Odeh, Y Zhang, SM Reilly, N Ebadat, O Keinan, JM Valentine, ... Cell reports 35 (13), 2021 | 80 | 2021 |
| Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration SM Reilly, P Bhargava, S Liu, MR Gangl, C Gorgun, RR Nofsinger, ... Cell metabolism 12 (6), 643-653, 2010 | 68 | 2010 |
| Chop/Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice J Yong, VS Parekh, SM Reilly, J Nayak, Z Chen, C Lebeaupin, I Jang, ... Science translational medicine 13 (604), eaba9796, 2021 | 58 | 2021 |
| Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes O Keinan, JM Valentine, H Xiao, SK Mahata, SM Reilly, M Abu-Odeh, ... Nature 599 (7884), 296-301, 2021 | 57 | 2021 |
| RalA controls glucose homeostasis by regulating glucose uptake in brown fat Y Skorobogatko, M Dragan, C Cordon, SM Reilly, CW Hung, W Xia, ... Proceedings of the National Academy of Sciences 115 (30), 7819-7824, 2018 | 51 | 2018 |
| Carboxylic acid derivatives of amlexanox display enhanced potency toward TBK1 and IKKε and reveal mechanisms for selective inhibition TS Beyett, X Gan, SM Reilly, L Chang, AV Gomez, AR Saltiel, ... Molecular pharmacology 94 (4), 1210-1219, 2018 | 44 | 2018 |
| Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3 SM Reilly, CW Hung, M Ahmadian, P Zhao, O Keinan, AV Gomez, ... Nature metabolism 2 (7), 620-634, 2020 | 42 | 2020 |
| Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation W Xia, P Veeragandham, Y Cao, Y Xu, TE Rhyne, J Qian, CW Hung, ... Nature Metabolism, 1-17, 2024 | 41 | 2024 |