| Structural basis for the autoinhibition of c-Abl tyrosine kinase B Nagar, O Hantschel, MA Young, K Scheffzek, D Veach, W Bornmann, ... Cell 112 (6), 859-871, 2003 | 1082 | 2003 |
| Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation MA Young, S Gonfloni, G Superti-Furga, B Roux, J Kuriyan Cell 105 (1), 115-126, 2001 | 509 | 2001 |
| Intrusion of counterions into the spine of hydration in the minor groove of B-DNA: fractional occupancy of electronegative pockets MA Young, B Jayaram, DL Beveridge Journal of the American Chemical Society 119 (1), 59-69, 1997 | 458 | 1997 |
| Molecular dynamics simulation of nucleic acids: successes, limitations, and promise TE Cheatham III, MA Young Biopolymers: Original Research on Biomolecules 56 (4), 232-256, 2000 | 453 | 2000 |
| A Src-like inactive conformation in the abl tyrosine kinase domain NM Levinson, O Kuchment, K Shen, MA Young, M Koldobskiy, M Karplus, ... PLoS biology 4 (5), e144, 2006 | 362 | 2006 |
| Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680 MA Young, NP Shah, LH Chao, M Seeliger, ZV Milanov, WH Biggs III, ... Cancer research 66 (2), 1007-1014, 2006 | 354 | 2006 |
| A 5-nanosecond molecular dynamics trajectory for B-DNA: analysis of structure, motions, and solvation MA Young, G Ravishanker, DL Beveridge Biophysical journal 73 (5), 2313-2336, 1997 | 346 | 1997 |
| Molecular dynamics simulations of the 136 unique tetranucleotide sequences of DNA oligonucleotides. I. Research design and results on d (CpG) steps DL Beveridge, G Barreiro, KS Byun, DA Case, TE Cheatham, SB Dixit, ... Biophysical journal 87 (6), 3799-3813, 2004 | 329 | 2004 |
| Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III D Jeruzalmi, O Yurieva, Y Zhao, M Young, J Stewart, M Hingorani, ... Cell 106 (4), 417-428, 2001 | 307 | 2001 |
| High yield bacterial expression of active c‐Abl and c‐Src tyrosine kinases MA Seeliger, M Young, MN Henderson, P Pellicena, DS King, AM Falick, ... Protein Science 14 (12), 3135-3139, 2005 | 286 | 2005 |
| Free energy analysis of the conformational preferences of A and B forms of DNA in solution B Jayaram, D Sprous, MA Young, DL Beveridge Journal of the American Chemical Society 120 (41), 10629-10633, 1998 | 231 | 1998 |
| Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases D Wisniewski, CL Lambek, C Liu, A Strife, DR Veach, B Nagar, MA Young, ... Cancer research 62 (15), 4244-4255, 2002 | 215 | 2002 |
| Emerging potential of therapeutic targeting of ubiquitin-specific proteases in the treatment of cancer A Pal, MA Young, NJ Donato Cancer research 74 (18), 4955-4966, 2014 | 213 | 2014 |
| Local dielectric environment of B-DNA in solution: results from a 14 ns molecular dynamics trajectory MA Young, B Jayaram, DL Beveridge The Journal of Physical Chemistry B 102 (39), 7666-7669, 1998 | 164 | 1998 |
| Molecular dynamics simulations of an oligonucleotide duplex with adenine tracts phased by a full helix turn MA Young, DL Beveridge Journal of molecular biology 281 (4), 675-687, 1998 | 156 | 1998 |
| Analysis of local helix bending in crystal structures of DNA oligonucleotides and DNA-protein complexes MA Young, G Ravishanker, DL Beveridge, HM Berman Biophysical journal 68 (6), 2454-2468, 1995 | 153 | 1995 |
| Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies LF Peterson, H Sun, Y Liu, H Potu, M Kandarpa, M Ermann, SM Courtney, ... Blood, The Journal of the American Society of Hematology 125 (23), 3588-3597, 2015 | 134 | 2015 |
| Transcription factor binding to a DNA zip code controls interchromosomal clustering at the nuclear periphery DG Brickner, S Ahmed, L Meldi, A Thompson, W Light, M Young, ... Developmental cell 22 (6), 1234-1246, 2012 | 125 | 2012 |
| Briefly bound to activate: transient binding of a second catalytic magnesium activates the structure and dynamics of CDK2 kinase for catalysis ZQ Bao, DM Jacobsen, MA Young Structure 19 (5), 675-690, 2011 | 113 | 2011 |
| Molecular dynamics studies of axis bending in d (G5-(GA4T4C) 2-C5) and d (G5-(GT4A4C) 2-C5): effects of sequence polarity on DNA curvature D Sprous, MA Young, DL Beveridge Journal of molecular biology 285 (4), 1623-1632, 1999 | 109 | 1999 |
John KuriyanProfessor of Molecular and Cell Biology and ChemistryOverená e-mailová adresa na: berkeley.edu