Targeting MIF in cancer: therapeutic strategies, current developments, and future opportunities C O'Reilly, M Doroudian, L Mawhinney, SC Donnelly Medicinal research reviews 36 (3), 440-460, 2016 | 158 | 2016 |
Macrophage Migration Inhibitory Factor (MIF) Enzymatic Activity and Lung Cancer SCD Leona Mawhinney, Michelle E Armstrong, Ciaran O’ Reilly, Richard Bucala ... Molecular Medicine 20 (1), 729-735, 2015 | 87* | 2015 |
Lanthanide luminescence from supramolecular hydrogels consisting of bio-conjugated picolinic-acid-based guanosine quadruplexes O Kotova, C O’Reilly, ST Barwich, LE Mackenzie, AD Lynes, ... Chem 8 (5), 1395-1414, 2022 | 38 | 2022 |
Synthesis of α-S-glycosphingolipids based on uronic acids C O’Reilly, PV Murphy Organic Letters 13 (19), 5168-5171, 2011 | 38 | 2011 |
Decorated macrocycles via ring-closing double-reductive amination. Identification of an apoptosis inducer of leukemic cells that at least partially antagonizes a 5-HT2 receptor J Zhou, M Reidy, C O’Reilly, DV Jarikote, A Negi, A Samali, E Szegezdi, ... Organic letters 17 (7), 1672-1675, 2015 | 29 | 2015 |
Aerosolized Drug-Loaded Nanoparticles Targeting Migration Inhibitory Factors Inhibit Pseudomonas Aeruginosa-Induced Inflammation and Biofilm Formation M Doroudian, A O’Neill, C O’Reilly, A Tynan, L Mawhinney, A McElroy, ... Nanomedicine 15 (30), 2933-2953, 2020 | 27 | 2020 |
Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis G Cooke, I Kamal, M Strengert, E Hams, L Mawhinney, A Tynan, ... QJM: An International Journal of Medicine 111 (4), 217-224, 2018 | 24 | 2018 |
Ultrasound-assisted synthesis of C-glycosides DV Jarikote, C O’Reilly, PV Murphy Tetrahedron Letters 51 (51), 6776-6778, 2010 | 22 | 2010 |
Synthesis of α-O- and α-S-Glycosphingolipids Related to Sphingomonous cell Wall Antigens Using Anomerisation W Pilgrim, C O’Reilly, PV Murphy Molecules 18 (9), 11198-11218, 2013 | 19 | 2013 |
Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis A Tynan, L Mawhinney, ME Armstrong, C O’Reilly, S Kennedy, E Caraher, ... The FASEB Journal 31 (11), 5102, 2017 | 18 | 2017 |
Ruthenium-centred btp glycoclusters as inhibitors for Pseudomonas aeruginosa biofilm formation C O'Reilly, S Blasco, B Parekh, H Collins, G Cooke, T Gunnlaugsson, ... RSC advances 11 (27), 16318-16325, 2021 | 14 | 2021 |
Multi-targeting protein-protein interaction inhibitors: Evolution of macrocyclic ligands with embedded carbohydrates (MECs) to improve selectivity A Negi, CO Reilly, DV Jarikote, J Zhou, PV Murphy European Journal of Medicinal Chemistry 176, 292-309, 2019 | 13 | 2019 |
Synthesis of a constrained polyfunctional bicyclic iminocyclitol scaffold from l-sorbose via a tandem sequence including stereoselective intramolecular Huisgen cycloaddition C O’Reilly, C O’Brien, PV Murphy Tetrahedron letters 50 (31), 4427-4429, 2009 | 12 | 2009 |
3-phenyl-7-hydroxy-isocoumarins as macrophage migration inhibitory factor (MIF) inhibitors S Donnelly, D Lloyd, C O'reilly, D Fayne US Patent 10,106,519, 2018 | 1 | 2018 |
Good things come in small packages: An aerosolized delivery system for small molecule inhibitors of macrophage migration inhibitory factor M Doroudian, C O'Reilly, K Crosbie-Staunton, R MacLoughlin, ... Irish J Med Sci, 2016 | 1 | 2016 |
Aerosolized nanodrug delivery system to inhibit Macrophage migration inhibitory factor in order to treat lung cancer M Doroudian, FE Poynton, C O'Reilly, K Crosbie-Staunton, ... Medicine 20 (1), 729-35, 2014 | 1 | 2014 |
Nicotinamide ripk1 inhibitors KP Cusack, MZ Hoemann, DA Kinsman, S Osman, JP Stambuli, ... US Patent App. 18/608,389, 2024 | | 2024 |
Nicotinamide RIPK1 inhibitors KP Cusack, MZ Hoemann, DA Kinsman, S Osman, JP Stambuli, ... US Patent 11,767,310, 2023 | | 2023 |
3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors S Donnelly, D Lloyd, C O'reilly, D Fayne US Patent App. 16/129,944, 2019 | | 2019 |
Toll- Like Receptor 3 (TLR3) L412F Single Nucleotide Polymorphism as a Causative Factor in Disease Progression in Idiopathic Pulmonary Fibrosis (IPF) During … AN McElroy, DN O'Dwyer, G Cooke, L Mawhinney, A Tynan, C O'Reilly, ... Irish Thoracic Society Annual Scientific Meeting 2016, 2016 | | 2016 |