Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis D Kaushal, TW Foreman, US Gautam, X Alvarez, T Adekambi, ... Nature communications 6 (1), 8533, 2015 | 220 | 2015 |
In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis US Gautam, TW Foreman, AN Bucsan, AV Veatch, X Alvarez, T Adekambi, ... Proceedings of the National Academy of Sciences 115 (1), E62-E71, 2018 | 197 | 2018 |
The DosR regulon modulates adaptive immunity and is essential for Mycobacterium tuberculosis persistence S Mehra, TW Foreman, PJ Didier, MH Ahsan, TA Hudock, R Kissee, ... American journal of respiratory and critical care medicine 191 (10), 1185-1196, 2015 | 184 | 2015 |
CD4+ T-cell–independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection TW Foreman, S Mehra, DN LoBato, A Malek, X Alvarez, NA Golden, ... Proceedings of the National Academy of Sciences 113 (38), E5636-E5644, 2016 | 135 | 2016 |
Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis CY Cheng, NM Gutierrez, MB Marzuki, X Lu, TW Foreman, B Paleja, ... Science immunology 2 (9), eaaj1789, 2017 | 123 | 2017 |
PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques KD Kauffman, S Sakai, NE Lora, S Namasivayam, PJ Baker, ... Science immunology 6 (55), eabf3861, 2021 | 109 | 2021 |
Host resistance to pulmonary Mycobacterium tuberculosis infection requires CD153 expression MA Sallin, KD Kauffman, C Riou, E Du Bruyn, TW Foreman, S Sakai, ... Nature microbiology 3 (11), 1198-1205, 2018 | 70 | 2018 |
Mechanisms of reactivation of latent tuberculosis infection due to SIV coinfection AN Bucşan, A Chatterjee, DK Singh, TW Foreman, TH Lee, B Threeton, ... The Journal of clinical investigation 129 (12), 5254-5260, 2019 | 68 | 2019 |
Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosis TA Hudock, TW Foreman, N Bandyopadhyay, US Gautam, AV Veatch, ... American journal of respiratory cell and molecular biology 56 (5), 637-647, 2017 | 64 | 2017 |
GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection EP Amaral, TW Foreman, S Namasivayam, KL Hilligan, KD Kauffman, ... Journal of Experimental Medicine 219 (11), e20220504, 2022 | 50 | 2022 |
The TB-specific CD4+ T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans BR Mothé, CSL Arlehamn, C Dow, MBC Dillon, RW Wiseman, P Bohn, ... Tuberculosis 95 (6), 722-735, 2015 | 49 | 2015 |
Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control RV Swanson, A Gupta, TW Foreman, L Lu, JA Choreno-Parra, SK Mbandi, ... Nature immunology 24 (5), 855-868, 2023 | 48 | 2023 |
Translational research in the nonhuman primate model of tuberculosis TW Foreman, S Mehra, AA Lackner, D Kaushal ILAR journal 58 (2), 151-159, 2017 | 46 | 2017 |
Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues CE Nelson, S Namasivayam, TW Foreman, KD Kauffman, S Sakai, ... Science immunology 7 (70), eabo0535, 2022 | 33 | 2022 |
Mucosal-activated invariant T cells do not exhibit significant lung recruitment and proliferation profiles in macaques in response to infection with Mycobacterium tuberculosis … AN Bucsan, N Rout, TW Foreman, SA Khader, J Rengarajan, D Kaushal Tuberculosis 116, S11-S18, 2019 | 29 | 2019 |
CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection TW Foreman, CE Nelson, KD Kauffman, NE Lora, CL Vinhaes, ... Cell Reports 39 (9), 2022 | 25 | 2022 |
LAG-3 potentiates the survival of Mycobacterium tuberculosis in host phagocytes by modulating mitochondrial signaling in an in-vitro granuloma model BL Phillips, US Gautam, AN Bucsan, TW Foreman, NA Golden, T Niu, ... PloS one 12 (9), e0180413, 2017 | 24 | 2017 |
Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques TW Foreman, AN Bucşan, S Mehra, C Peloquin, LA Doyle, ... American journal of respiratory and critical care medicine 201 (4), 469-477, 2020 | 18 | 2020 |
Nonpathologic infection of macaques by an attenuated mycobacterial vaccine is not reactivated in the setting of HIV co-infection TW Foreman, AV Veatch, DN LoBato, PJ Didier, LA Doyle-Meyers, ... The American journal of pathology 187 (12), 2811-2820, 2017 | 18 | 2017 |
Isoniazid and rifapentine treatment effectively reduces persistent M. tuberculosis infection in macaque lungs R Sharan, SR Ganatra, DK Singh, J Cole, TW Foreman, R Thippeshappa, ... The Journal of Clinical Investigation 132 (18), 2022 | 14 | 2022 |