| Tau reduction prevents Aβ-induced defects in axonal transport KA Vossel, K Zhang, J Brodbeck, AC Daub, P Sharma, S Finkbeiner, ... Science 330 (6001), 198-198, 2010 | 591 | 2010 |
| Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells J Barclay, N Balaguero, M Mione, SL Ackerman, VA Letts, J Brodbeck, ... Journal of Neuroscience 21 (16), 6095-6104, 2001 | 411 | 2001 |
| Effect of selective LRRK2 kinase inhibition on nonhuman primate lung RN Fuji, M Flagella, M Baca, MA S. Baptista, J Brodbeck, BK Chan, ... Science translational medicine 7 (273), 273ra15-273ra15, 2015 | 304 | 2015 |
| The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated α2δ-2 protein with abnormal function J Brodbeck, A Davies, JM Courtney, A Meir, N Balaguero, C Canti, ... Journal of Biological Chemistry 277 (10), 7684-7693, 2002 | 210 | 2002 |
| Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons HK Chen, Z Liu, A Meyer-Franke, J Brodbeck, RD Miranda, JG McGuire, ... Journal of Biological Chemistry 287 (8), 5253-5266, 2012 | 167 | 2012 |
| Intron-3 retention/splicing controls neuronal expression of apolipoprotein E in the CNS Q Xu, D Walker, A Bernardo, J Brodbeck, ME Balestra, Y Huang Journal of Neuroscience 28 (6), 1452-1459, 2008 | 131 | 2008 |
| Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons J Brodbeck, ME Balestra, AM Saunders, AD Roses, RW Mahley, Y Huang Proceedings of the National Academy of Sciences 105 (4), 1343-1346, 2008 | 123 | 2008 |
| Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors J Brodbeck, J McGuire, Z Liu, A Meyer-Franke, ME Balestra, D Jeong, ... Journal of biological chemistry 286 (19), 17217-17226, 2011 | 118 | 2011 |
| Translational and therapeutic evaluation of RAS-GTP inhibition by RMC-6236 in RAS-driven cancers J Jiang, L Jiang, BJ Maldonato, Y Wang, M Holderfield, I Aronchik, ... Cancer Discovery 14 (6), 994-1017, 2024 | 68 | 2024 |
| Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Nature 629 (8013), 927-936, 2024 | 57 | 2024 |
| Voltage‐dependent binding and calcium channel current inhibition by an anti‐α1D subunit antibody in rat dorsal root ganglion neurones and guinea‐pig myocytes CN Wyatt, V Campbell, J Brodbeck, NL Brice, KM Page, NS Berrow, ... The Journal of Physiology 502 (2), 307-319, 1997 | 53 | 1997 |
| Arf4 determines dentate gyrus-mediated pattern separation by regulating dendritic spine development S Jain, SY Yoon, L Zhu, J Brodbeck, J Dai, D Walker, Y Huang Public Library of Science 7 (9), e46340, 2012 | 50 | 2012 |
| The role of glomerular epithelial injury in kidney function decline in patients with diabetic kidney disease in the TRIDENT cohort MB Palmer, A Abedini, C Jackson, S Blady, S Chatterjee, KM Sullivan, ... Kidney international reports 6 (4), 1066-1080, 2021 | 33 | 2021 |
| Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells A Aggarwal, PM Odorizzi, J Brodbeck, N van Buuren, C Moon, S Chang, ... JHEP Reports 5 (4), 100664, 2023 | 16 | 2023 |
| Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer MA Jarzabek, WR Proctor, J Vogt, R Desai, P Dicker, G Cain, R Raja, ... PLoS One 13 (6), e0198099, 2018 | 13 | 2018 |
| P2‐157: Apolipoprotein E4 impairs mitochondrial function and increases reactive oxygen species in neuronal cells J Brodbeck, RD Miranda, SB Freedman, KH Weisgraber, RW Mahley, ... Alzheimer's & Dementia 5 (4S_Part_10), P307-P307, 2009 | 8 | 2009 |
| Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Nature, 1-1, 2024 | 5 | 2024 |
| O3‐03–03: Apolipoprotein E4 and its fragment impair mitochondrial dynamics in neuronal cultures J Brodbeck, M Balestra, S Freedman, KH Weisgraber, RW Mahley, ... Alzheimer's & Dementia 4, T163-T163, 2008 | 5 | 2008 |
| Mucosal p-STAT1/3 correlates with histologic disease activity in Crohn’s disease and is responsive to filgotinib W Reinisch, A Serone, X Hébuterne, T Kühbacher, M Kłopocka, X Roblin, ... Tissue Barriers 11 (2), 2088961, 2023 | 3 | 2023 |
| Methods of identifying agents that modulate mitochondrial function Y Huang, J Brodbeck US Patent 8,512,958, 2013 | 3 | 2013 |
Yadong Huang, MD, PhD.Senior Investigator, Gladstone Institute of Neurological Disease, Professor of Neurology, UCSFOverená e-mailová adresa na: gladstone.ucsf.edu
