Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition SJ Hogg, O Motorna, LA Cluse, TM Johanson, HD Coughlan, R Raviram, ... Molecular cell 81 (10), 2183-2200. e13, 2021 | 101 | 2021 |
Transcription-factor-mediated supervision of global genome architecture maintains B cell identity TM Johanson, ATL Lun, HD Coughlan, T Tan, GK Smyth, SL Nutt, ... Nature immunology 19 (11), 1257-1264, 2018 | 101 | 2018 |
Transcription factor PU. 1 promotes conventional dendritic cell identity and function via induction of transcriptional regulator DC-SCRIPT M Chopin, AT Lun, Y Zhan, J Schreuder, H Coughlan, A D’Amico, ... Immunity 50 (1), 77-90. e5, 2019 | 95 | 2019 |
Multi-level remodelling of chromatin underlying activation of human T cells NG Bediaga, HD Coughlan, TM Johanson, AL Garnham, G Naselli, ... Scientific reports 11 (1), 528, 2021 | 53 | 2021 |
An Erg-driven transcriptional program controls B cell lymphopoiesis AP Ng, HD Coughlan, S Hediyeh-Zadeh, K Behrens, TM Johanson, ... Nature Communications 11 (1), 3013, 2020 | 44 | 2020 |
Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT S Zhang, HD Coughlan, M Ashayeripanah, S Seizova, AJ Kueh, ... Science immunology 6 (58), eabf4432, 2021 | 31 | 2021 |
Genome-wide analysis reveals no evidence of trans chromosomal regulation of mammalian immune development TM Johanson, HD Coughlan, ATL Lun, NG Bediaga, G Naselli, ... PLoS genetics 14 (6), e1007431, 2018 | 30* | 2018 |
Pre-mitotic genome re-organisation bookends the B cell differentiation process WF Chan, HD Coughlan, JHS Zhou, CR Keenan, NG Bediaga, ... Nature Communications 12 (1), 1344, 2021 | 22 | 2021 |
Radiation damage in a micron-sized protein crystal studied via reciprocal space mapping and Bragg coherent diffractive imaging HD Coughlan, C Darmanin, NW Phillips, F Hofmann, JN Clark, RJ Harder, ... Structural Dynamics 2 (4), 2015 | 21 | 2015 |
Bragg coherent diffraction imaging and metrics for radiation damage in protein micro-crystallography HD Coughlan, C Darmanin, HJ Kirkwood, NW Phillips, D Hoxley, JN Clark, ... Synchrotron Radiation 24 (1), 83-94, 2017 | 20 | 2017 |
Phase-diverse Fresnel coherent diffractive imaging of malaria parasite-infected red blood cells in the water window MWM Jones, B Abbey, A Gianoncelli, E Balaur, C Millet, MB Luu, ... Optics Express 21 (26), 32151-32159, 2013 | 20 | 2013 |
Nanocrystallography measurements of early stage synthetic malaria pigment RA Dilanian, V Streltsov, HD Coughlan, HM Quiney, AV Martin, N Klonis, ... Applied Crystallography 50 (5), 1533-1540, 2017 | 18 | 2017 |
Activation of stably silenced genes by recruitment of a synthetic de-methylating module WF Chan, HD Coughlan, Y Chen, CR Keenan, GK Smyth, AC Perkins, ... Nature Communications 13 (1), 5582, 2022 | 13 | 2022 |
Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes CR Keenan, MJ Mlodzianoski, HD Coughlan, NG Bediaga, G Naselli, ... IScience 24 (3), 2021 | 10 | 2021 |
Three-dimensional reconstruction of the size and shape of protein microcrystals using Bragg coherent diffractive imaging HD Coughlan, C Darmanin, HJ Kirkwood, NW Phillips, D Hoxley, JN Clark, ... Journal of optics 18 (5), 054003, 2016 | 10 | 2016 |
Ptychographic Fresnel coherent diffraction tomography at the nanoscale NW Phillips, CT Putkunz, G Van Riessen, HD Coughlan, MWM Jones, ... International journal of materials research 105 (7), 655-663, 2014 | 9 | 2014 |
Nanoscale mapping of the three-dimensional deformation field within commercial nanodiamonds MS Maqbool, D Hoxley, NW Phillips, HD Coughlan, C Darmanin, ... International Journal of Nanotechnology 14 (1-6), 251-264, 2017 | 8 | 2017 |
Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis Y Zhan, Y Zhang, S Zhang, H Coughlan, PL Baldoni, N Jacquelot, ... Science Immunology 6 (63), eabf7268, 2021 | 7 | 2021 |
Identification and characterization of the long noncoding RNA Dreg1 as a novel regulator of Gata3 WF Chan, HD Coughlan, N Iannarella, GK Smyth, TM Johanson, ... Immunology and Cell Biology 99 (3), 323-332, 2021 | 7 | 2021 |
Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription CR Keenan, HD Coughlan, N Iannarella, AT Del Fierro, A Keniry, ... Genome Research 34 (4), 556-571, 2024 | 6 | 2024 |