Charge variants in IgG1: isolation, characterization, in vitro binding properties and pharmacokinetics in rats LA Khawli, S Goswami, R Hutchinson, ZW Kwong, J Yang, X Wang, Z Yao, ... MAbs 2 (6), 613-624, 2010 | 451 | 2010 |
Catalytic hydrolysis of DNA by metal ions and complexes A Sreedhara, JA Cowan JBIC Journal of Biological Inorganic Chemistry 6, 337-347, 2001 | 347 | 2001 |
Efficient inorganic deoxyribonucleases. Greater than 50-million-fold rate enhancement in enzyme-like DNA cleavage A Sreedhara, JD Freed, JA Cowan Journal of the American Chemical Society 122 (37), 8814-8824, 2000 | 279 | 2000 |
Establishing a link between amino acid sequences and self-associating and viscoelastic behavior of two closely related monoclonal antibodies S Yadav, A Sreedhara, S Kanai, J Liu, S Lien, H Lowman, DS Kalonia, ... Pharmaceutical research 28, 1750-1764, 2011 | 154 | 2011 |
Ligating DNA with DNA A Sreedhara, Y Li, RR Breaker Journal of the American Chemical Society 126 (11), 3454-3460, 2004 | 131 | 2004 |
A novel in vitro method to model the fate of subcutaneously administered biopharmaceuticals and associated formulation components HM Kinnunen, V Sharma, LR Contreras-Rojas, Y Yu, C Alleman, ... Journal of Controlled Release 214, 94-102, 2015 | 115 | 2015 |
Alkoxo bound monooxo-and dioxovanadium (V) complexes: synthesis, characterization, X-ray crystal structures, and solution reactivity studies G Asgedom, A Sreedhara, J Kivikoski, J Valkonen, E Kolehmainen, ... Inorganic chemistry 35 (19), 5674-5683, 1996 | 113 | 1996 |
Structural and catalytic roles for divalent magnesium in nucleic acid biochemistry A Sreedhara, JA Cowan Biometals 15 (3), 211-223, 2002 | 106 | 2002 |
Stability of IgG1 monoclonal antibodies in intravenous infusion bags under clinical in-use conditions A Sreedhara, ZK Glover, N Piros, N Xiao, A Patel, B Kabakoff Journal of pharmaceutical sciences 101 (1), 21-30, 2012 | 99 | 2012 |
A new roadmap for biopharmaceutical drug product development: Integrating development, validation, and quality by design S Martin‐Moe, FJ Lim, RL Wong, A Sreedhara, J Sundaram, SU Sane Journal of pharmaceutical sciences 100 (8), 3031-3043, 2011 | 93 | 2011 |
Effect of ambient light on IgG1 monoclonal antibodies during drug product processing and development A Sreedhara, J Yin, M Joyce, K Lau, AT Wecksler, G Deperalta, L Yi, ... European Journal of Pharmaceutics and Biopharmaceutics 100, 38-46, 2016 | 87 | 2016 |
Compatibility and stability of pertuzumab and trastuzumab admixtures in iv infusion bags for coadministration ZWK Glover, L Gennaro, S Yadav, B Demeule, PY Wong, A Sreedhara Journal of pharmaceutical sciences 102 (3), 794-812, 2013 | 71 | 2013 |
Characterization of the isomerization products of aspartate residues at two different sites in a monoclonal antibody A Sreedhara, A Cordoba, Q Zhu, J Kwong, J Liu Pharmaceutical research 29, 187-197, 2012 | 69 | 2012 |
Synthesis and characterization of vanadyl (IV) complexes of Schiff bases derived from anthranilic acid and salicylaldehyde (or its derivatives) or acetylacetone. Single crystal … G Asgedom, A Sreedhara, J Kivikoski, CP Rao Polyhedron 16 (4), 643-651, 1997 | 69 | 1997 |
Structure, characterization and photoreactivity of monomeric dioxovanadium (V) Schiff-base complexes of trigonal-bipyramidal geometry G Asgedom, A Sreedhara, J Kivikoski, E Kolehmainen, CP Rao Journal of the Chemical Society, Dalton Transactions, 93-97, 1996 | 67 | 1996 |
Syntheses, structure, reactivity and species recognition studies of oxo-vanadium (V) and-molybdenum (VI) complexes CP Rao, P áVenkateswara Rao, M áBindu Verghese, ... Journal of the Chemical Society, Dalton Transactions, 2383-2394, 1998 | 63 | 1998 |
Stress factors in mAb drug substance production processes: critical assessment of impact on product quality and control strategy TK Das, LO Narhi, A Sreedhara, T Menzen, C Grapentin, DK Chou, ... Journal of Pharmaceutical Sciences 109 (1), 116-133, 2020 | 59 | 2020 |
Biodegradable microparticles that stabilize and control the release of proteins S Alavattam, RS Brody US Patent 7,060,299, 2006 | 59 | 2006 |
Metal ion interactions with mAbs: Part 1: pH and conformation modulate copper-mediated site-specific fragmentation of the IgG1 hinge region ZK Glover, L Basa, B Moore, JS Laurence, A Sreedhara MAbs 7 (5), 901-911, 2015 | 58 | 2015 |
Role of surface exposed tryptophan as substrate generators for the antibody catalyzed water oxidation pathway A Sreedhara, K Lau, C Li, B Hosken, F Macchi, D Zhan, A Shen, ... Molecular Pharmaceutics 10 (1), 278-288, 2013 | 57 | 2013 |