| Visceral leishmaniasis treatment: what do we have, what do we need and how to deliver it? LH Freitas-Junior, E Chatelain, HA Kim, JL Siqueira-Neto International Journal for Parasitology: Drugs and Drug Resistance 2, 11-19, 2012 | 381 | 2012 |
| Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds JL Siqueira-Neto, OR Song, H Oh, JH Sohn, G Yang, J Nam, J Jang, ... PLoS neglected tropical diseases 4 (5), e675, 2010 | 185 | 2010 |
| Cysteine proteases in protozoan parasites JL Siqueira-Neto, A Debnath, LI McCall, JA Bernatchez, M Ndao, ... PLoS neglected tropical diseases 12 (8), e0006512, 2018 | 180 | 2018 |
| An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages JL Siqueira-Neto, S Moon, J Jang, G Yang, C Lee, HK Moon, E Chatelain, ... PLoS neglected tropical diseases 6 (6), e1671, 2012 | 179 | 2012 |
| Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ... Cell stem cell 26 (2), 187-204. e10, 2020 | 168 | 2020 |
| Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ... Journal of Experimental Medicine 216 (5), 1071-1090, 2019 | 125 | 2019 |
| Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase LI McCall, A El Aroussi, JY Choi, DF Vieira, G De Muylder, JB Johnston, ... PLoS neglected tropical diseases 9 (3), e0003588, 2015 | 120 | 2015 |
| A clinical-stage cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells DM Mellott, CT Tseng, A Drelich, P Fajtová, BC Chenna, DH Kostomiris, ... ACS chemical biology 16 (4), 642-650, 2021 | 113 | 2021 |
| Drugs for the treatment of Zika virus infection JA Bernatchez, LT Tran, J Li, Y Luan, JL Siqueira-Neto, R Li Journal of medicinal chemistry 63 (2), 470-489, 2019 | 105 | 2019 |
| Antimalarial drug discovery: progress and approaches JL Siqueira-Neto, KJ Wicht, K Chibale, JN Burrows, DA Fidock, ... Nature Reviews Drug Discovery 22 (10), 807-826, 2023 | 94 | 2023 |
| Genome-directed lead discovery: biosynthesis, structure elucidation, and biological evaluation of two families of polyene macrolactams against Trypanosoma brucei CJ Schulze, MS Donia, JL Siqueira-Neto, D Ray, JA Raskatov, RE Green, ... ACS chemical biology 10 (10), 2373-2381, 2015 | 93 | 2015 |
| Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery S Ekins, J Lage de Siqueira-Neto, LI McCall, M Sarker, M Yadav, ... PLoS neglected tropical diseases 9 (6), e0003878, 2015 | 88 | 2015 |
| Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ... Scientific reports 8 (1), 1218, 2018 | 80 | 2018 |
| Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni … NC Fonseca, LF da Cruz, F da Silva Villela, GA do Nascimento Pereira, ... Antimicrobial Agents and Chemotherapy 59 (5), 2666-2677, 2015 | 79 | 2015 |
| Open drug discovery for the Zika virus S Ekins, D Mietchen, M Coffee, TP Stratton, JS Freundlich, ... F1000Research 5, 150, 2016 | 74 | 2016 |
| Synthesis and biological evaluation of 2, 3-dihydroimidazo [1, 2-a] benzimidazole derivatives against Leishmania donovani and Trypanosoma cruzi S Oh, S Kim, S Kong, G Yang, N Lee, D Han, J Goo, JL Siqueira-Neto, ... European Journal of Medicinal Chemistry 84, 395-403, 2014 | 65 | 2014 |
| Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi EF Silva-Júnior, EPS Silva, PHB França, JPN Silva, EO Barreto, EB Silva, ... Bioorganic & medicinal chemistry 24 (18), 4228-4240, 2016 | 62 | 2016 |
| Current and future chemotherapy for Chagas disease L Gaspar, C B Moraes, L H Freitas-Junior, S Ferrari, L Costantino, ... Current medicinal chemistry 22 (37), 4293-4312, 2015 | 61 | 2015 |
| Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window AK Singh, RK Pandey, JL Siqueira-Neto, YJ Kwon, LH Freitas-Junior, ... Infection and immunity 83 (5), 1853-1868, 2015 | 60 | 2015 |
| 4-Aminopyridyl-Based CYP51 Inhibitors as Anti-Trypanosoma cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency CM Calvet, DF Vieira, JY Choi, D Kellar, MD Cameron, JL Siqueira-Neto, ... Journal of medicinal chemistry 57 (16), 6989-7005, 2014 | 59 | 2014 |
James McKerrowDean, University of California San DiegoOverená e-mailová adresa na: health.ucsd.edu