Margarida Amaral

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	Všetky	Od 2020
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Carlos Miguel FarinhaAssociate Professor of BiochemistryOverená e-mailová adresa na: fc.ul.pt
Luka A. ClarkeBIOISI: Biosystems & Integrative Sciences Institute, University of Lisbon, PortugalOverená e-mailová adresa na: fc.ul.pt
Hugo M. BotelhoBioISI - Faculdade de Ciências, Universidade de LisboaOverená e-mailová adresa na: ciencias.ulisboa.pt
Nikhil T AwatadeUniversity of NewcastleOverená e-mailová adresa na: newcastle.edu.au
Rainer PepperkokTeamleader, EMBL, Heidelberg GermanyOverená e-mailová adresa na: embl.de
Dr Daniel GrahamFaculty of Science Senior Research Officer, LJMUOverená e-mailová adresa na: ljmu.ac.uk
Hugo Alexandre FerreiraIBEB, Faculdade de Ciências da Universidade de Lisboa, PortugalOverená e-mailová adresa na: fc.ul.pt
Scott BellOverená e-mailová adresa na: health.qld.gov.au
Philip J ThomasProfessor UT SouthwesternOverená e-mailová adresa na: utsouthwestern.edu
Rachel KarchinProfessor of Biomedical Engineering, Oncology and Computer Science, Johns Hopkins UniversityOverená e-mailová adresa na: jhu.edu
Maria de Fatima Corrêa Pimenta Servi...Medica gastropediatra Gastrocentro e FCM-UNICAMPOverená e-mailová adresa na: gc.unicamp.br
Gergely L. LukacsMcGill UniversityOverená e-mailová adresa na: mcgill.ca
Richard I. MorimotoBill and Gayle Cook Professor of Biology, Dept of Molecular Biosciences, NorthwesternOverená e-mailová adresa na: northwestern.edu
Michael A GrayNewcastle UniversityOverená e-mailová adresa na: newcastle.ac.uk
Jose Dirceu RibeiroSate University of Campinas - UNICAMP - BrazilOverená e-mailová adresa na: unicamp.br
Rui MalhóOverená e-mailová adresa na: fc.ul.pt
Luis P FonsecaAssociate Professor, Bioengineering Departament, Instituto Superior TécnicoOverená e-mailová adresa na: tecnico.ulisboa.pt
Joaquim M S CabralDistinguished Professor of Bioengineering, Instituto Superior Técnico, University of LisbonOverená e-mailová adresa na: tecnico.ulisboa.pt
Cláudio M. GomesFaculty of Sciences University of Lisbon, BioISI and Department of Chemistry and BiochemistryOverená e-mailová adresa na: fc.ul.pt
Margarida RamosProfessor, Faculty of Science University of LisbonOverená e-mailová adresa na: fc.ul.pt

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Margarida Amaral

Professor of Molecular Biology, Faculty of Sciences, University of Lisboa

Overená e-mailová adresa na: fc.ul.pt - Domovská stránka

Molecular & Cell Biology Membrane Proteins Cystic Fibrosis


Názov Zoradiť podľa citácií Zoradiť podľa roka Zoradiť podľa názvu	Citované v Citované v	Rok
Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene PR Sosnay, KR Siklosi, F Van Goor, K Kaniecki, H Yu, N Sharma, ... Nature genetics 45 (10), 1160-1167, 2013	726	2013
Progress in therapies for cystic fibrosis K De Boeck, MD Amaral The Lancet Respiratory Medicine 4 (8), 662-674, 2016	549	2016
Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei D Zink, MD Amaral, A Englmann, S Lang, LA Clarke, C Rudolph, F Alt, ... Journal of Cell Biology 166 (6), 815-825, 2004	323	2004
CFTR modulator theratyping: Current status, gaps and future directions JP Clancy, CU Cotton, SH Donaldson, GM Solomon, DR VanDevanter, ... Journal of Cystic Fibrosis 18 (1), 22-34, 2019	289	2019
Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin CM Farinha, MD Amaral Molecular and cellular biology 25 (12), 5242-5252, 2005	263	2005
New pharmacological approaches for cystic fibrosis: promises, progress, pitfalls SC Bell, K De Boeck, MD Amaral Pharmacology & therapeutics 145, 19-34, 2015	259	2015
CFTR and chaperones: processing and degradation MD Amaral Journal of Molecular Neuroscience 23, 41-48, 2004	221	2004
Five percent of normal cystic fibrosis transmembrane conductance regulator mRNA ameliorates the severity of pulmonary disease in cystic fibrosis AS Ramalho, S Beck, M Meyer, D Penque, GR Cutting, MD Amaral American journal of respiratory cell and molecular biology 27 (5), 619-627, 2002	216	2002
Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction CM Farinha, J King-Underwood, M Sousa, AR Correia, BJ Henriques, ... Chemistry & biology 20 (7), 943-955, 2013	197	2013
Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis MD Amaral, K Kunzelmann Trends in pharmacological sciences 28 (7), 334-341, 2007	188	2007
Novel personalized therapies for cystic fibrosis: treating the basic defect in all patients MD Amaral Journal of internal medicine 277 (2), 155-166, 2015	173	2015
The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator … CM Farinha, P Nogueira, F Mendes, D Penque, MD Amaral Biochemical Journal 366 (3), 797-806, 2002	170	2002
CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis S Hirtz, T Gonska, HH Seydewitz, J Thomas, P Greiner, J Kuehr, ... Gastroenterology 127 (4), 1085-1095, 2004	162	2004
Processing of CFTR: traversing the cellular maze—how much CFTR needs to go through to avoid cystic fibrosis? MD Amaral Pediatric pulmonology 39 (6), 479-491, 2005	160	2005
Epithelial chloride transport by CFTR requires TMEM16A R Benedetto, J Ousingsawat, P Wanitchakool, Y Zhang, MJ Holtzman, ... Scientific reports 7 (1), 12397, 2017	143	2017
A genetic screening strategy identifies novel regulators of the proteostasis network MC Silva, S Fox, M Beam, H Thakkar, MD Amaral, RI Morimoto PLoS genetics 7 (12), e1002438, 2011	139	2011
Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms M Roxo-Rosa, Z Xu, A Schmidt, M Neto, Z Cai, CM Soares, DN Sheppard, ... Proceedings of the National Academy of Sciences 103 (47), 17891-17896, 2006	139	2006
Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells SM Garcia, MO Casanueva, MC Silva, MD Amaral, RI Morimoto Genes & development 21 (22), 3006-3016, 2007	133	2007
Magnetic field-assisted DNA hybridisation and simultaneous detection using micron-sized spin-valve sensors and magnetic nanoparticles DL Graham, HA Ferreira, N Feliciano, PP Freitas, LA Clarke, MD Amaral Sensors and Actuators B: Chemical 107 (2), 936-944, 2005	131	2005
Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells D Penque, F Mendes, S Beck, C Farinha, P Pacheco, P Nogueira, ... Laboratory investigation 80 (6), 857-868, 2000	125	2000

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