| Human IFNAR2 deficiency: Lessons for antiviral immunity CJA Duncan, SMB Mohamad, DF Young, AJ Skelton, TR Leahy, ... Science translational medicine 7 (307), 307ra154-307ra154, 2015 | 246 | 2015 |
| Symptom-based stratification of patients with primary Sjögren's syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised … JR Tarn, N Howard-Tripp, DW Lendrem, X Mariette, A Saraux, ... The Lancet Rheumatology 1 (2), e85-e94, 2019 | 129 | 2019 |
| Early-onset autoimmunity associated with SOCS1 haploinsufficiency J Hadjadj, CN Castro, M Tusseau, MC Stolzenberg, F Mazerolles, ... Nature communications 11 (1), 5341, 2020 | 118 | 2020 |
| Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2 CJA Duncan, BJ Thompson, R Chen, GI Rice, F Gothe, DF Young, ... Science immunology 4 (42), eaav7501, 2019 | 113 | 2019 |
| The long non-coding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells MJ Barter, R Gomez, S Hyatt, K Cheung, AJ Skelton, Y Xu, IM Clark, ... Development 144 (24), 4510-4521, 2017 | 82 | 2017 |
| Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20) CJA Duncan, E Dinnigan, R Theobald, A Grainger, AJ Skelton, R Hussain, ... Annals of the rheumatic diseases 77 (5), 783-786, 2018 | 80 | 2018 |
| Cytokine-induced MMP13 expression in human chondrocytes is dependent on activating transcription factor 3 (ATF3) regulation CM Chan, CD Macdonald, GJ Litherland, DJ Wilkinson, A Skelton, ... Journal of Biological Chemistry 292 (5), 1625-1636, 2017 | 61 | 2017 |
| Predicting drug-free remission in rheumatoid arthritis: a prospective interventional cohort study KF Baker, AJ Skelton, DW Lendrem, A Scadeng, B Thompson, AG Pratt, ... Journal of autoimmunity 105, 102298, 2019 | 58 | 2019 |
| Functional Characterization of the Osteoarthritis Genetic Risk Residing at ALDH1A2 Identifies rs12915901 as a Key Target Variant C Shepherd, D Zhu, AJ Skelton, J Combe, H Threadgold, L Zhu, ... Arthritis & Rheumatology 70 (10), 1577-1587, 2018 | 55 | 2018 |
| CD4+ and B lymphocyte expression quantitative traits at rheumatoid arthritis risk loci in patients with untreated early arthritis: implications for causal gene identification N Thalayasingam, N Nair, AJ Skelton, J Massey, AE Anderson, AD Clark, ... Arthritis & Rheumatology 70 (3), 361-370, 2018 | 54 | 2018 |
| Prioritization of PLEC and GRINA as Osteoarthritis Risk Genes Through the Identification and Characterization of Novel Methylation Quantitative Trait Loci SJ Rice, M Tselepi, AK Sorial, G Aubourg, C Shepherd, D Almarza, ... Arthritis & rheumatology 71 (8), 1285-1296, 2019 | 46 | 2019 |
| Identification of long non-coding RNAs expressed in knee and hip osteoarthritic cartilage B Ajekigbe, K Cheung, Y Xu, AJ Skelton, A Panagiotopoulos, J Soul, ... Osteoarthritis and Cartilage 27 (4), 694-702, 2019 | 45 | 2019 |
| Phenotypic and transcriptomic analysis of peripheral blood plasmacytoid and conventional dendritic cells in early drug naïve rheumatoid arthritis FAH Cooles, AE Anderson, A Skelton, AG Pratt, MS Kurowska-Stolarska, ... Frontiers in immunology 9, 755, 2018 | 43 | 2018 |
| Leptin and pro-inflammatory stimuli synergistically upregulate MMP-1 and MMP-3 secretion in human gingival fibroblasts RC Williams, AJ Skelton, SM Todryk, AD Rowan, PM Preshaw, JJ Taylor PloS one 11 (2), e0148024, 2016 | 38 | 2016 |
| Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci AD Clark, N Nair, AE Anderson, N Thalayasingam, N Naamane, ... Journal of allergy and clinical immunology 145 (5), 1438-1451, 2020 | 32 | 2020 |
| DNA hypomethylation during MSC chondrogenesis occurs predominantly at enhancer regions MJ Barter, C Bui, K Cheung, J Falk, R Gómez, AJ Skelton, HR Elliott, ... Scientific Reports 10 (1), 1169, 2020 | 32 | 2020 |
| Il-6 mediated transcriptional programming of naïve CD4+ T cells in early rheumatoid arthritis drives dysregulated effector function LA Ridgley, AE Anderson, NJ Maney, N Naamane, AJ Skelton, ... Frontiers in immunology 10, 1535, 2019 | 31 | 2019 |
| Expression of STAT3-regulated genes in circulating CD4+ T cells discriminates rheumatoid arthritis independently of clinical parameters in early arthritis AE Anderson, NJ Maney, N Nair, DW Lendrem, AJ Skelton, J Diboll, ... Rheumatology 58 (7), 1250-1258, 2019 | 29 | 2019 |
| Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874 C Shepherd, AJ Skelton, MD Rushton, LN Reynard, J Loughlin BMC Medical Genetics 16, 1-11, 2015 | 26 | 2015 |
| microRNA-seq of cartilage reveals an overabundance of miR-140-3p which contains functional isomiRs S Woods, S Charlton, K Cheung, Y Hao, J Soul, LN Reynard, N Crowe, ... Rna 26 (11), 1575-1588, 2020 | 24 | 2020 |