| Vaccines for established cancer: overcoming the challenges posed by immune evasion SH van der Burg, R Arens, F Ossendorp, T van Hall, CJM Melief Nature Reviews Cancer 16 (4), 219-233, 2016 | 756 | 2016 |
| Therapeutic cancer vaccines CJM Melief, T van Hall, R Arens, F Ossendorp, SH van der Burg The Journal of clinical investigation 125 (9), 3401-3412, 2015 | 713 | 2015 |
| Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNγ-mediated B cell depletion R Arens, K Tesselaar, PA Baars, GMW Van Schijndel, J Hendriks, ST Pals, ... Immunity 15 (5), 801-812, 2001 | 341 | 2001 |
| Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions K Tesselaar, R Arens, GMW van Schijndel, PA Baars, MA van Der Valk, ... Nature immunology 4 (1), 49-54, 2003 | 316 | 2003 |
| Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells S Feau, R Arens, S Togher, SP Schoenberger Nature immunology 12 (9), 908-913, 2011 | 309 | 2011 |
| The activation of the adaptive immune system: cross-talk between antigen-presenting cells, T cells and B cells JMM den Haan, R Arens, MC van Zelm Immunology letters 162 (2), 103-112, 2014 | 293 | 2014 |
| Plasticity in programming of effector and memory CD8+ T‐cell formation R Arens, SP Schoenberger Immunological reviews 235 (1), 190-205, 2010 | 291 | 2010 |
| Expression of the murine CD27 ligand CD70 in vitro and in vivo K Tesselaar, Y Xiao, R Arens, GMW van Schijndel, DH Schuurhuis, ... The Journal of Immunology 170 (1), 33-40, 2003 | 257 | 2003 |
| In vivo killing capacity of cytotoxic T cells is limited and involves dynamic interactions and T cell cooperativity S Halle, KA Keyser, FR Stahl, A Busche, A Marquardt, X Zheng, M Galla, ... Immunity 44 (2), 233-245, 2016 | 253 | 2016 |
| Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-Cell–Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects MF Fransen, TC Van Der Sluis, F Ossendorp, R Arens, CJM Melief Clinical cancer research 19 (19), 5381-5389, 2013 | 228 | 2013 |
| Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses MJ Welters, TC van der Sluis, H van Meir, NM Loof, VJ van Ham, ... Science translational medicine 8 (334), 334ra52-334ra52, 2016 | 217 | 2016 |
| Sustained antibody responses depend on CD28 function in bone marrow–resident plasma cells CH Rozanski, R Arens, LM Carlson, J Nair, LH Boise, AA Chanan-Khan, ... Journal of Experimental Medicine 208 (7), 1435-1446, 2011 | 217 | 2011 |
| Tumor Rejection Induced by CD70-mediated Quantitative and Qualitative Effects on Effector CD8+ T Cell Formation R Arens, K Schepers, MA Nolte, MF van Oosterwijk, RAW van Lier, ... The Journal of experimental medicine 199 (11), 1595-1605, 2004 | 193 | 2004 |
| New advances in CMV and immunosenescence P Sansoni, R Vescovini, FF Fagnoni, A Akbar, R Arens, YL Chiu, ... Experimental gerontology 55, 54-62, 2014 | 176 | 2014 |
| Local activation of CD8 T cells and systemic tumor eradication without toxicity via slow release and local delivery of agonistic CD40 antibody MF Fransen, M Sluijter, H Morreau, R Arens, CJM Melief Clinical Cancer Research 17 (8), 2270-2280, 2011 | 176 | 2011 |
| Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient JWJ van Heijst, C Gerlach, E Swart, D Sie, C Nunes-Alves, RM Kerkhoven, ... Science 325 (5945), 1265-1269, 2009 | 175 | 2009 |
| B cells are crucial for both development and maintenance of the splenic marginal zone MA Nolte, R Arens, M Kraus, MHJ Van Oers, G Kraal, RAW van Lier, ... The Journal of Immunology 172 (6), 3620-3627, 2004 | 171 | 2004 |
| Signaling through CD70 regulates B cell activation and IgG production R Arens, MA Nolte, K Tesselaar, B Heemskerk, KA Reedquist, ... The Journal of Immunology 173 (6), 3901-3908, 2004 | 169 | 2004 |
| Memory T cell inflation: understanding cause and effect GA O’Hara, SPM Welten, P Klenerman, R Arens Trends in immunology 33 (2), 84-90, 2012 | 168 | 2012 |
| The CD4+ T-cell help signal is transmitted from APC to CD8+ T-cells via CD27–CD70 interactions S Feau, Z Garcia, R Arens, H Yagita, J Borst, SP Schoenberger Nature communications 3 (1), 948, 2012 | 165 | 2012 |
