De novo pathogenic variants in CACNA1E cause developmental and epileptic encephalopathy with contractures, macrocephaly, and dyskinesias KL Helbig, RJ Lauerer, JC Bahr, IA Souza, CT Myers, B Uysal, N Schwarz, ... The American Journal of Human Genetics 103 (5), 666-678, 2018 | 129 | 2018 |
Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons EJ López Soto, F Agosti, A Cabral, ER Mustafa, VM Damonte, MA Gandini, ... Journal of General Physiology 146 (3), 205-219, 2015 | 71 | 2015 |
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N-and T … SS Bellampalli, Y Ji, A Moutal, S Cai, EMK Wijeratne, MA Gandini, J Yu, ... Pain 160 (1), 117-135, 2019 | 61 | 2019 |
RIM1/2-mediated facilitation of Cav1. 4 channel opening is required for Ca2+-stimulated release in mouse rod photoreceptors CP Grabner, MA Gandini, R Rehak, Y Le, GW Zamponi, F Schmitz Journal of Neuroscience 35 (38), 13133-13147, 2015 | 61 | 2015 |
Hyperactivity of innate immunity triggers pain via TLR2-IL-33-mediated neuroimmune crosstalk J Huang, MA Gandini, L Chen, S M’Dahoma, PL Stemkowski, H Chung, ... Cell Reports 33 (1), 2020 | 42 | 2020 |
Voltage‐gated calcium channel nanodomains: molecular composition and function MA Gandini, GW Zamponi The FEBS journal 289 (3), 614-633, 2022 | 40 | 2022 |
CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated … MA Gandini, DR Henríquez, L Grimaldo, A Sandoval, C Altier, ... Pflügers Archiv-European Journal of Physiology 466, 2113-2126, 2014 | 39 | 2014 |
Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release MA Gandini, A Sandoval, R González-Ramírez, Y Mori, M de Waard, ... Journal of Biological Chemistry 286 (18), 15757-15765, 2011 | 39 | 2011 |
Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of CaV2. 1 voltage-gated calcium channels E Garza-López, A Sandoval, R González-Ramírez, MA Gandini, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (8 …, 2012 | 38 | 2012 |
Functional interactions between voltage-gated Ca2+ channels and Rab3-interacting molecules (RIMs): New insights into stimulus–secretion coupling MA Gandini, R Felix Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (3), 551-558, 2012 | 32 | 2012 |
Regulation of L-type CaV1. 3 channel activity and insulin secretion by the cGMP-PKG signaling pathway A Sandoval, P Duran, MA Gandini, A Andrade, A Almanza, S Kaja, R Felix Cell Calcium 66, 1-9, 2017 | 31 | 2017 |
CaV3. 2 calcium channels contribute to trigeminal neuralgia E Gambeta, MA Gandini, IA Souza, GW Zamponi Pain 163 (12), 2315-2325, 2022 | 30 | 2022 |
Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol EK Harding, IA Souza, MA Gandini, VM Gadotti, MY Ali, S Huang, ... British Journal of Pharmacology 180 (12), 1616-1633, 2023 | 28 | 2023 |
Two heterozygous Cav3. 2 channel mutations in a pediatric chronic pain patient: recording condition-dependent biophysical effects IA Souza, MA Gandini, MM Wan, GW Zamponi Pflügers Archiv-European Journal of Physiology 468 (4), 635-642, 2016 | 27 | 2016 |
Maitotoxin: An enigmatic toxic molecule with useful applications in the biomedical sciences JG Reyes, C Sánchez-Cárdenas, W Acevedo-Castillo, P Leyton, ... Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection …, 2014 | 25 | 2014 |
The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels MA Gandini, A Sandoval, GW Zamponi, R Felix Channels 8 (5), 452-457, 2014 | 24 | 2014 |
Patch-clamp recording of voltage-sensitive Ca2+ channels MA Gandini, A Sandoval, R Felix Cold Spring Harbor Protocols 2014 (4), pdb. top066092, 2014 | 24 | 2014 |
Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP−/− Mice J Fan, PL Stemkowski, MA Gandini, SA Black, Z Zhang, IA Souza, L Chen, ... Frontiers in cellular neuroscience 10, 74, 2016 | 23 | 2016 |
Discovery of Michael acceptor containing 1, 4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels HA Cevher, D Schaller, MA Gandini, O Kaplan, E Gambeta, FX Zhang, ... Bioorganic Chemistry 91, 103187, 2019 | 22 | 2019 |
A CACNA1A variant associated with trigeminal neuralgia alters the gating of Cav2. 1 channels E Gambeta, MA Gandini, IA Souza, L Ferron, GW Zamponi Molecular Brain 14, 1-6, 2021 | 21 | 2021 |