| HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways F Guo, Q Zhao, M Sheraz, J Cheng, Y Qi, Q Su, A Cuconati, L Wei, Y Du, ... PLoS pathogens 13 (9), e1006658, 2017 | 130 | 2017 |
| Detection of a novel reactive metabolite of diclofenac: evidence for CYP2C9-mediated bioactivation via arene oxides Z Yan, J Li, N Huebert, GW Caldwell, Y Du, H Zhong Drug Metabolism and Disposition 33 (6), 706-713, 2005 | 110 | 2005 |
| Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses J Chang, TK Warren, X Zhao, T Gill, F Guo, L Wang, MA Comunale, Y Du, ... Antiviral research 98 (3), 432-440, 2013 | 98 | 2013 |
| Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B U Viswanathan, N Mani, Z Hu, H Ban, Y Du, J Hu, J Chang, JT Guo Antiviral research 182, 104917, 2020 | 95 | 2020 |
| Synthesis of nonracemic dimethyl α-(hydroxyfarnesyl) phosphonates via oxidation of dimethyl farnesylphosphonate with (camphorsulfonyl) oxaziridines DM Cermak, Y Du, DF Wiemer The Journal of Organic Chemistry 64 (2), 388-393, 1999 | 82 | 1999 |
| Design, synthesis, and conformational analysis of eight-membered cyclic peptidomimetics prepared using ring closing metathesis CJ Creighton, GC Leo, Y Du, AB Reitz Bioorganic & medicinal chemistry 12 (16), 4375-4385, 2004 | 69 | 2004 |
| Design, Synthesis, and Biological Evaluation of N-Alkylated Deoxynojirimycin (DNJ) Derivatives for the Treatment of Dengue Virus Infection W Yu, T Gill, L Wang, Y Du, H Ye, X Qu, JT Guo, A Cuconati, K Zhao, ... Journal of medicinal chemistry 55 (13), 6061-6075, 2012 | 65 | 2012 |
| A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists B Liu, L Tang, X Zhang, J Ma, M Sehgal, J Cheng, X Zhang, Y Zhou, Y Du, ... Antiviral research 147, 37-46, 2017 | 64 | 2017 |
| Discovery and mechanistic study of a novel human-stimulator-of-interferon-genes agonist X Zhang, B Liu, L Tang, Q Su, N Hwang, M Sehgal, J Cheng, J Ma, ... ACS infectious diseases 5 (7), 1139-1149, 2019 | 54 | 2019 |
| Discovery and mechanistic study of benzamide derivatives that modulate hepatitis B virus capsid assembly S Wu, Q Zhao, P Zhang, J Kulp, L Hu, N Hwang, J Zhang, TM Block, X Xu, ... Journal of virology 91 (16), 10.1128/jvi. 00519-17, 2017 | 54 | 2017 |
| A novel benzodiazepine compound inhibits yellow fever virus infection by specifically targeting NS4B protein F Guo, S Wu, J Julander, J Ma, X Zhang, J Kulp, A Cuconati, TM Block, ... Journal of virology 90 (23), 10774-10788, 2016 | 48 | 2016 |
| Discovery of novel hepatitis B virus nucleocapsid assembly inhibitors X Zhang, J Cheng, J Ma, Z Hu, S Wu, N Hwang, J Kulp, Y Du, JT Guo, ... ACS infectious diseases 5 (5), 759-768, 2018 | 43 | 2018 |
| A one-flask synthesis of α, α-bisphosphonates via enolate chemistry Y Du, KY Jung, DF Wiemer Tetrahedron letters 43 (48), 8665-8668, 2002 | 43 | 2002 |
| The synthesis and evaluation of 10-and 12-membered ring benzofused enediyne amino acids Y Du, CJ Creighton, Z Yan, DA Gauthier, JP Dahl, B Zhao, SM Belkowski, ... Bioorganic & medicinal chemistry 13 (21), 5936-5948, 2005 | 34 | 2005 |
| Noncovalent self-assembly of bicyclo [4.2. 2] diketopiperazines: influence of saturation in the bridging carbacyclic ring Y Du, CJ Creighton, BA Tounge, AB Reitz Organic Letters 6 (3), 309-312, 2004 | 34 | 2004 |
| Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo J Ma, X Zhang, V Soloveva, T Warren, F Guo, S Wu, H Lu, J Guo, Q Su, ... Antiviral research 150, 112-122, 2018 | 33 | 2018 |
| Preparation of α-phosphono lactams via electrophilic phosphorus reagents: An application in the synthesis of lactam-based farnesyl transferase inhibitors Y Du, DF Wiemer The Journal of Organic Chemistry 67 (16), 5709-5717, 2002 | 32 | 2002 |
| Imino sugar glucosidase inhibitors as broadly active anti-filovirus agents J Chang, JT Guo, Y Du, T Block Emerging microbes & infections 2 (1), 1-7, 2013 | 29 | 2013 |
| The renaissance of CDK inhibitors in breast cancer therapy: An update on clinical trials and therapy resistance M Abdelmalak, R Singh, M Anwer, P Ivanchenko, A Randhawa, M Ahmed, ... Cancers 14 (21), 5388, 2022 | 26 | 2022 |
| Quassinoid analogs with enhanced efficacy for treatment of hematologic malignancies target the PI3Kγ isoform Y Pei, N Hwang, F Lang, L Zhou, JH Wong, RK Singh, HC Jha, ... Communications Biology 3 (1), 267, 2020 | 26 | 2020 |
