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Ian R. Outhwaite
Ian R. Outhwaite
Ďalšie menáIan Outhwaite
Overená e-mailová adresa na: stonybrookmedicine.edu
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Citované v
Citované v
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Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
X Hou, IR Outhwaite, L Pedi, SB Long
Elife 9, e62772, 2020
572020
Discovery and molecular basis of subtype-selective cyclophilin inhibitors
AA Peterson, AM Rangwala, MK Thakur, PS Ward, C Hung, IR Outhwaite, ...
Nature Chemical Biology 18 (11), 1184-1195, 2022
262022
Allosteric regulation and inhibition of protein kinases
VR Mingione, YT Paung, IR Outhwaite, MA Seeliger
Biochemical Society Transactions 51 (1), 373-385, 2023
142023
Motivation to Impact: Medical Student Volunteerism in the COVID 19 Pandemic.
HE Phillips, RB Jennings, IR Outhwaite, S Grosser, M Chandra, V Ende, ...
Medical Science Educator, 2022
132022
Lucanthone, a potential PPT1 inhibitor, perturbs stemness, reduces tumor microtube formation, and slows the growth of temozolomide-resistant gliomas in vivo
DP Radin, S Shifman, IR Outhwaite, A Sharma, R Bases, MA Seeliger, ...
The Journal of Pharmacology and Experimental Therapeutics 389 (1), 51-60, 2024
42024
Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting
IR Outhwaite, S Singh, BT Berger, S Knapp, JD Chodera, MA Seeliger
Elife 12, e86189, 2023
32023
Probing conformational dynamics to understand kinase inhibition
IR Outhwaite, MA Seeliger
Elife 12, e92753, 2023
32023
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib
A Leyte-Vidal, RA DeFilippis, IR Outhwaite, I Kwan, JY Lee, C Leavitt, ...
Leukemia 38 (9), 2046-2050, 2024
22024
Death by a thousand cuts–combining kinase inhibitors for selective target inhibition and rational polypharmacology
IR Outhwaite, S Singh, BT Berger, S Knapp, JD Chodera, MA Seeliger
bioRxiv, 2023.01. 13.523972, 2023
12023
The Effects of the Physical and Professional Workplace Environments on the Well-Being of Nursing Staff
R Jennings, I Outhwaite, I Granek, F Haq
AJN The American Journal of Nursing 125 (3), 30-39, 2025
2025
Resistance to Allosteric Inhibitors
I Outhwaite, I Kwan, NP Shah, I Bahar, MA Seeliger
Available at SSRN 5135932, 0
Cryo-EM structure of the calcium release-activated calcium channel
X Hou, IR Outhwaite, L Pedi, SB Long
Systém momentálne nemôže vykonať operáciu. Skúste to neskôr.
Články 1–12