| The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. L Shi, G Campbell, WD Jones, F Campagne, Z Wen, SJ Walker, Z Su, ... Nature biotechnology 28 (8), 2010 | 901 | 2010 |
| ToxCast chemical landscape: paving the road to 21st century toxicology AM Richard, RS Judson, KA Houck, CM Grulke, P Volarath, ... Chemical research in toxicology 29 (8), 1225-1251, 2016 | 659 | 2016 |
| Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment BA Wetmore, JF Wambaugh, SS Ferguson, MA Sochaski, DM Rotroff, ... Toxicological Sciences 125 (1), 157-174, 2012 | 493 | 2012 |
| Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice GP Lahvis, SL Lindell, RS Thomas, RS McCuskey, C Murphy, E Glover, ... Proceedings of the National Academy of Sciences 97 (19), 10442-10447, 2000 | 487 | 2000 |
| A comparison of batch effect removal methods for enhancement of prediction performance using MAQC-II microarray gene expression data J Luo, M Schumacher, A Scherer, D Sanoudou, D Megherbi, T Davison, ... The pharmacogenomics journal 10 (4), 278-291, 2010 | 373 | 2010 |
| Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening DM Rotroff, BA Wetmore, DJ Dix, SS Ferguson, HJ Clewell, KA Houck, ... Toxicological Sciences 117 (2), 348-358, 2010 | 318 | 2010 |
| Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing BA Wetmore, JF Wambaugh, B Allen, SS Ferguson, MA Sochaski, ... Toxicological Sciences 148 (1), 121-136, 2015 | 311 | 2015 |
| Toxicity testing in the 21st century: progress in the past decade and future perspectives D Krewski, ME Andersen, MG Tyshenko, K Krishnan, T Hartung, ... Archives of toxicology 94, 1-58, 2020 | 310 | 2020 |
| The next generation blueprint of computational toxicology at the US Environmental Protection Agency RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ... Toxicological Sciences 169 (2), 317-332, 2019 | 306 | 2019 |
| Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ... Toxicological Sciences 148 (1), 137-154, 2015 | 302 | 2015 |
| Identification of toxicologically predictive gene sets using cDNA microarrays RS Thomas, DR Rank, SG Penn, GM Zastrow, KR Hayes, K Pande, ... Molecular Pharmacology 60 (6), 1189-1194, 2001 | 298 | 2001 |
| Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ... Toxicological Sciences 152 (2), 323-339, 2016 | 280 | 2016 |
| Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework RS Thomas, MA Philbert, SS Auerbach, BA Wetmore, MJ Devito, I Cote, ... toxicological sciences 136 (1), 4-18, 2013 | 276 | 2013 |
| Screening chemicals for estrogen receptor bioactivity using a computational model P Browne, RS Judson, WM Casey, NC Kleinstreuer, RS Thomas Environmental science & technology 49 (14), 8804-8814, 2015 | 273 | 2015 |
| Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment RS Judson, RJ Kavlock, RW Setzer, EA Cohen Hubal, MT Martin, ... Chemical research in toxicology 24 (4), 451-462, 2011 | 234 | 2011 |
| A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure RS Thomas, BC Allen, A Nong, L Yang, E Bermudez, HJ Clewell III, ... Toxicological sciences 98 (1), 240-248, 2007 | 221 | 2007 |
| The Tox21 10K compound library: collaborative chemistry advancing toxicology AM Richard, R Huang, S Waidyanatha, P Shinn, BJ Collins, ... Chemical Research in Toxicology 34 (2), 189-216, 2020 | 220 | 2020 |
| Temporal concordance between apical and transcriptional points of departure for chemical risk assessment RS Thomas, SC Wesselkamper, NCY Wang, QJ Zhao, DD Petersen, ... Toxicological Sciences 134 (1), 180-194, 2013 | 217 | 2013 |
| The US Federal Tox21 Program: A strategic and operational plan for continued leadership RS Thomas, RS Paules, A Simeonov, SC Fitzpatrick, KM Crofton, ... Altex 35 (2), 163, 2018 | 211 | 2018 |
| Development and validation of a computational model for androgen receptor activity NC Kleinstreuer, P Ceger, ED Watt, M Martin, K Houck, P Browne, ... Chemical research in toxicology 30 (4), 946-964, 2017 | 204 | 2017 |
Richard JudsonUS EPA, Center for Computational Toxicology and ExposureOverená e-mailová adresa na: epa.gov
