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Russell Taylor Walton
Russell Taylor Walton
MIT Department of Biological Engineering and the Broad Institute of MIT and Harvard
Preverjeni e-poštni naslov na mit.edu
Naslov
Navedeno
Navedeno
Leto
Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants
RT Walton, KA Christie, MN Whittaker, BP Kleinstiver
Science 368 (6488), 290-296, 2020
10742020
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ...
Nature biotechnology 37 (3), 276-282, 2019
6502019
Discovery of widespread type I and type V CRISPR-Cas inhibitors
ND Marino, JY Zhang, AL Borges, AA Sousa, LM Leon, BJ Rauch, ...
Science 362 (6411), 240-242, 2018
2602018
Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program
Y Hu, AM Stilp, CP McHugh, S Rao, D Jain, X Zheng, J Lane, ...
The American Journal of Human Genetics 108 (5), 874-893, 2021
542021
Precise DNA cleavage using CRISPR-SpRYgests
KA Christie, JA Guo, RA Silverstein, RM Doll, M Mabuchi, HE Stutzman, ...
Nature biotechnology 41 (3), 409-416, 2023
422023
Scalable characterization of the PAM requirements of CRISPR–Cas enzymes using HT-PAMDA
RT Walton, JY Hsu, JK Joung, BP Kleinstiver
Nature protocols 16 (3), 1511-1547, 2021
362021
Pooled genetic screens with image‐based profiling
RT Walton, A Singh, PC Blainey
Molecular Systems Biology 18 (11), e10768, 2022
162022
CROPseq-multi: a versatile solution for multiplexed perturbation and decoding in pooled CRISPR screens
RT Walton, Y Qin, PC Blainey
bioRxiv, 2024
62024
Unconstrained Genome Targeting with near-PAMless Engineered CRISPR-Cas9 Variants
B Kleinstiver, RT Walton
US Patent App. 17/157,708, 2021
12021
Crispr-cas enzymes with enhanced on-target activity
B Kleinstiver, RT Walton
US Patent App. 17/157,805, 2021
12021
Methods to characterize enzymes for genome engineering
B Kleinstiver, RT Walton
US Patent App. 17/794,520, 2023
2023
Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing (vol 37, pg 276, 2019)
BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ...
NATURE BIOTECHNOLOGY 38 (7), 901-901, 2020
2020
Unconstrained Genome Targeting with Engineered Near-PAMless CRISPR-Cas Variants
KA Christie, RT Walton, BP Kleinstiver
MOLECULAR THERAPY 28 (4), 37-38, 2020
2020
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