| Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation M Xue, N Rabbani, H Momiji, P Imbasi, MM Anwar, N Kitteringham, ... Biochemical Journal 443 (1), 213-222, 2012 | 318 | 2012 |
| Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity T Souma, SW Tompson, BR Thomson, OM Siggs, K Kizhatil, S Yamaguchi, ... The Journal of clinical investigation 126 (7), 2575-2587, 2016 | 224 | 2016 |
| Perfluorinated chemicals as emerging environmental threats to kidney health: a scoping review JW Stanifer, HM Stapleton, T Souma, A Wittmer, X Zhao, LE Boulware Clinical journal of the American Society of Nephrology 13 (10), 1479-1492, 2018 | 219 | 2018 |
| Plasticity of renal erythropoietin-producing cells governs fibrosis T Souma, S Yamazaki, T Moriguchi, N Suzuki, I Hirano, X Pan, ... Journal of the American Society of Nephrology 24 (10), 1599-1616, 2013 | 207 | 2013 |
| Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression M Nezu, T Souma, L Yu, T Suzuki, D Saigusa, S Ito, N Suzuki, ... Kidney international 91 (2), 387-401, 2017 | 199 | 2017 |
| Erythropoietin synthesis in renal myofibroblasts is restored by activation of hypoxia signaling T Souma, M Nezu, D Nakano, S Yamazaki, I Hirano, H Sekine, T Dan, ... Journal of the American Society of Nephrology 27 (2), 428-438, 2016 | 178 | 2016 |
| Erythromyeloid progenitors give rise to a population of osteoclasts that contribute to bone homeostasis and repair Y Yahara, T Barrientos, YJ Tang, V Puviindran, P Nadesan, H Zhang, ... Nature cell biology 22 (1), 49-59, 2020 | 151 | 2020 |
| SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation T Toyohara, T Suzuki, R Morimoto, Y Akiyama, T Souma, HO Shiwaku, ... Journal of the American Society of Nephrology 20 (12), 2546-2555, 2009 | 147 | 2009 |
| Renal erythropoietin-producing cells in health and disease T Souma, N Suzuki, M Yamamoto Frontiers in physiology 6, 167, 2015 | 146 | 2015 |
| Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation P Liu, J Wysocki, T Souma, M Ye, V Ramirez, B Zhou, LD Wilsbacher, ... Kidney international 94 (1), 114-125, 2018 | 126 | 2018 |
| Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP T Souma, BR Thomson, S Heinen, I Anna Carota, S Yamaguchi, T Onay, ... Proceedings of the National Academy of Sciences 115 (6), 1298-1303, 2018 | 117 | 2018 |
| Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair S Ide, Y Kobayashi, K Ide, SA Strausser, K Abe, S Herbek, LL O'Brien, ... Elife 10, e68603, 2021 | 114 | 2021 |
| Angiopoietin-1 is required for Schlemm’s canal development in mice and humans BR Thomson, T Souma, SW Tompson, T Onay, K Kizhatil, OM Siggs, ... The Journal of clinical investigation 127 (12), 4421-4436, 2017 | 113 | 2017 |
| A mouse model of adult-onset anaemia due to erythropoietin deficiency S Yamazaki, T Souma, I Hirano, X Pan, N Minegishi, N Suzuki, ... Nature communications 4 (1), 1950, 2013 | 92 | 2013 |
| Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes M Nezu, T Souma, L Yu, H Sekine, N Takahashi, AZS Wei, S Ito, ... Science signaling 10 (479), eaam5711, 2017 | 91 | 2017 |
| Hypoxia signaling cascade for erythropoietin production in hepatocytes Y Tojo, H Sekine, I Hirano, X Pan, T Souma, T Tsujita, S Kawaguchi, ... Molecular and cellular biology 35 (15), 2658-2672, 2015 | 86 | 2015 |
| Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells N Miyazawa, M Abe, T Souma, M Tanemoto, T Abe, M Nakayama, S Ito Free radical research 44 (1), 101-107, 2010 | 80 | 2010 |
| Targeting VE-PTP phosphatase protects the kidney from diabetic injury IA Carota, Y Kenig-Kozlovsky, T Onay, R Scott, BR Thomson, T Souma, ... Journal of Experimental Medicine 216 (4), 936-949, 2019 | 50 | 2019 |
| GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts L Yu, T Moriguchi, T Souma, J Takai, H Satoh, N Morito, JD Engel, ... Molecular and cellular biology 34 (11), 1929-1941, 2014 | 46 | 2014 |
| SVEP1 as a genetic modifier of TEK-related primary congenital glaucoma TL Young, KN Whisenhunt, J Jin, SM LaMartina, SM Martin, T Souma, ... Investigative ophthalmology & visual science 61 (12), 6-6, 2020 | 43 | 2020 |