Long-term culture of genome-stable bipotent stem cells from adult human liver M Huch, H Gehart, R Van Boxtel, K Hamer, F Blokzijl, MMA Verstegen, ... Cell 160 (1), 299-312, 2015 | 1612 | 2015 |
Tales from the crypt: new insights into intestinal stem cells H Gehart, H Clevers Nature reviews Gastroenterology & hepatology 16 (1), 19-34, 2019 | 933 | 2019 |
Long-term expansion of functional mouse and human hepatocytes as 3D organoids H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ... Cell 175 (6), 1591-1606. e19, 2018 | 710 | 2018 |
MAPK signalling in cellular metabolism: stress or wellness? H Gehart, S Kumpf, A Ittner, R Ricci EMBO reports 11 (11), 834-840, 2010 | 360 | 2010 |
Identification of enteroendocrine regulators by real-time single-cell differentiation mapping H Gehart, JH van Es, K Hamer, J Beumer, K Kretzschmar, JF Dekkers, ... Cell 176 (5), 1158-1173. e16, 2019 | 306 | 2019 |
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell stem cell 28 (5), 816-832, 2021 | 240 | 2021 |
Chuva de Sousa Lopes, SM; Begthel, H.; Korving, J.; et al. Long-term expansion of functional mouse and human hepatocytes as 3D organoids H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ... Cell 175 (6), 1591-1606, 2018 | 190 | 2018 |
Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1 MA Kerenyi, F Grebien, H Gehart, M Schifrer, M Artaker, B Kovacic, ... Blood, The Journal of the American Society of Hematology 112 (9), 3878-3888, 2008 | 138 | 2008 |
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma E De Crignis, T Hossain, S Romal, F Carofiglio, P Moulos, MM Khalid, ... Elife 10, e60747, 2021 | 124 | 2021 |
Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung A Ittner, H Block, CA Reichel, M Varjosalo, H Gehart, G Sumara, ... Journal of Experimental Medicine 209 (12), 2229-2246, 2012 | 107 | 2012 |
Exploring the human lacrimal gland using organoids and single-cell sequencing M Bannier-Hélaouët, Y Post, J Korving, MT Bustos, H Gehart, H Begthel, ... Cell stem cell 28 (7), 1221-1232. e7, 2021 | 103 | 2021 |
The BAR domain protein Arfaptin-1 controls secretory granule biogenesis at the trans-Golgi network H Gehart, A Goginashvili, R Beck, J Morvan, E Erbs, I Formentini, ... Developmental cell 23 (4), 756-768, 2012 | 95 | 2012 |
Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease MMA Verstegen, FJM Roos, K Burka, H Gehart, M Jager, M de Wolf, ... Scientific reports 10 (1), 21900, 2020 | 80 | 2020 |
NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor L Novellasdemunt, A Kucharska, C Jamieson, M Prange‐Barczynska, ... The EMBO journal 39 (3), e102771, 2020 | 79 | 2020 |
The intestinal epithelium–fluid fate and rigid structure from crypt bottom to villus tip V Bonis, C Rossell, H Gehart Frontiers in cell and developmental biology 9, 661931, 2021 | 69 | 2021 |
Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure EW Kuijk, S Rasmussen, F Blokzijl, M Huch, H Gehart, P Toonen, ... Scientific reports 6 (1), 22154, 2016 | 63 | 2016 |
Enteroendocrine dynamics–new tools reveal hormonal plasticity in the gut J Beumer, H Gehart, H Clevers Endocrine reviews 41 (5), bnaa018, 2020 | 55 | 2020 |
A human organoid model of aggressive hepatoblastoma for disease modeling and drug testing JA Saltsman, WJ Hammond, NJC Narayan, D Requena, H Gehart, ... Cancers 12 (9), 2668, 2020 | 53 | 2020 |
Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease HS Kruitwagen, LA Oosterhoff, ME van Wolferen, C Chen, ... Cells 9 (2), 410, 2020 | 53 | 2020 |
Repairing organs: lessons from intestine and liver H Gehart, H Clevers Trends in Genetics 31 (6), 344-351, 2015 | 32 | 2015 |