Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies Nature communications 9 (1), 5269, 2018 | 360 | 2018 |
Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature S Wolking, E Schaeffeler, H Lerche, M Schwab, AT Nies Clinical pharmacokinetics 54, 709-735, 2015 | 302 | 2015 |
Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals YCA Feng, DP Howrigan, LE Abbott, K Tashman, F Cerrato, T Singh, ... The American Journal of Human Genetics 105 (2), 267-282, 2019 | 274 | 2019 |
Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study P May, S Girard, M Harrer, DR Bobbili, J Schubert, S Wolking, F Becker, ... The Lancet Neurology 17 (8), 699-708, 2018 | 95 | 2018 |
Carbamazepine‐and oxcarbazepine‐induced hyponatremia in people with epilepsy B Berghuis, J van der Palen, GJ de Haan, D Lindhout, BPC Koeleman, ... Epilepsia 58 (7), 1227-1233, 2017 | 93 | 2017 |
Frequent genes in rare diseases: panel‐based next generation sequencing to disclose causal mutations in hereditary neuropathies MF Dohrn, N Glöckle, L Mulahasanovic, C Heller, J Mohr, C Bauer, ... Journal of neurochemistry 143 (5), 507-522, 2017 | 82 | 2017 |
GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture Nature genetics 55 (9), 1471-1482, 2023 | 75 | 2023 |
Clinical spectrum of STX1B-related epileptic disorders S Wolking, P May, D Mei, RS Møller, S Balestrini, KL Helbig, CD Altuzarra, ... Neurology 92 (11), e1238-e1249, 2019 | 69 | 2019 |
Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells … MW Ronellenfitsch, DP Brucker, MC Burger, S Wolking, F Tritschler, ... Brain 132 (6), 1509-1522, 2009 | 65 | 2009 |
Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects LM Niestroj, E Perez-Palma, DP Howrigan, Y Zhou, F Cheng, ... Brain 143 (7), 2106-2118, 2020 | 64 | 2020 |
Early-onset familial hemiplegic migraine due to a novel SCN1A mutation C Fan, S Wolking, F Lehmann-Horn, UBS Hedrich, T Freilinger, H Lerche, ... Cephalalgia 36 (13), 1238-1247, 2016 | 59 | 2016 |
The modified ultrasound pattern sum score mUPSS as additional diagnostic tool for genetically distinct hereditary neuropathies A Grimm, M Rasenack, IM Athanasopoulou, NM Dammeier, C Lipski, ... Journal of neurology 263, 221-230, 2016 | 55 | 2016 |
Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients M McCormack, H Gui, A Ingason, D Speed, GEB Wright, EJ Zhang, ... Neurology 90 (4), e332-e341, 2018 | 49 | 2018 |
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis G Androsova, R Krause, M Borghei, M Wassenaar, P Auce, A Avbersek, ... Epilepsia 58 (10), 1734-1741, 2017 | 49 | 2017 |
Comparative effectiveness of antiepileptic drugs in juvenile myoclonic epilepsy K Silvennoinen, N de Lange, S Zagaglia, S Balestrini, G Androsova, ... Epilepsia Open 4 (3), 420-430, 2019 | 48 | 2019 |
Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals JE Motelow, G Povysil, RS Dhindsa, KE Stanley, AS Allen, YCA Feng, ... The American Journal of Human Genetics 108 (6), 965-982, 2021 | 46 | 2021 |
Focal epilepsy in glucose transporter type 1 (Glut1) defects: case reports and a review of literature S Wolking, F Becker, T Bast, A Wiemer-Kruel, T Mayer, H Lerche, ... Journal of neurology 261, 1881-1886, 2014 | 40 | 2014 |
Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study S Wolking, H Schulz, AT Nies, M McCormack, E Schaeffeler, P Auce, ... Pharmacogenomics 21 (5), 325-335, 2020 | 34 | 2020 |
Testing association of rare genetic variants with resistance to three common antiseizure medications S Wolking, C Moreau, AT Nies, E Schaeffeler, M McCormack, P Auce, ... Epilepsia 61 (4), 657-666, 2020 | 32 | 2020 |
Genome-wide identification and phenotypic characterization of seizure-associated copy number variations in 741,075 individuals L Montanucci, D Lewis-Smith, RL Collins, LM Niestroj, S Parthasarathy, ... Nature communications 14 (1), 4392, 2023 | 30 | 2023 |