| Colorimetric dipstick for assay of organophosphate pesticides and nerve agents represented by paraoxon, sarin and VX M Pohanka, JZ Karasova, K Kuca, J Pikula, O Holas, J Korabecny, ... Talanta 81 (1-2), 621-624, 2010 | 99 | 2010 |
| The progress in the cholinesterase quantification methods O Holas, K Musilek, M Pohanka, K Kuca Expert opinion on drug discovery 7 (12), 1207-1223, 2012 | 92 | 2012 |
| Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease J Korabecny, K Musilek, O Holas, J Binder, F Zemek, J Marek, M Pohanka, ... Bioorganic & medicinal chemistry letters 20 (20), 6093-6095, 2010 | 91 | 2010 |
| Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and … K Musilek, O Holas, K Kuca, D Jun, V Dohnal, V Opletalova, M Dolezal Journal of enzyme inhibition and medicinal chemistry 23 (1), 70-76, 2008 | 74 | 2008 |
| Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase Z Kovarik, M Katalinić, G Šinko, J Binder, O Holas, YS Jung, L Musilova, ... Chemico-biological interactions 187 (1-3), 167-171, 2010 | 73 | 2010 |
| Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker—Preparation and reactivation of tabun-and paraoxon-inhibited acetylcholinesterase K Musilek, O Holas, D Jun, V Dohnal, F Gunn-Moore, V Opletalova, ... Bioorganic & medicinal chemistry 15 (21), 6733-6741, 2007 | 73 | 2007 |
| Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1, 3-diyl linkage—Preparation, in vitro screening and molecular docking K Musilek, M Komloova, O Holas, A Horova, M Pohanka, F Gunn-Moore, ... Bioorganic & medicinal chemistry 19 (2), 754-762, 2011 | 66 | 2011 |
| Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon … K Musilek, O Holas, K Kuca, D Jun, V Dohnal, M Dolezal Journal of Enzyme Inhibition and Medicinal Chemistry 22 (4), 425-432, 2007 | 64 | 2007 |
| Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker—Synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited … K Musilek, O Holas, K Kuca, D Jun, V Dohnal, V Opletalova, M Dolezal Bioorganic & medicinal chemistry letters 17 (11), 3172-3176, 2007 | 62 | 2007 |
| PLGA based nanospheres as a potent macrophage-specific drug delivery system B Boltnarova, J Kubackova, J Skoda, A Stefela, M Smekalova, ... Nanomaterials 11 (3), 749, 2021 | 55 | 2021 |
| Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage—initial study for Myasthenia gravis implications K Musilek, M Komloova, V Zavadova, O Holas, M Hrabinova, M Pohanka, ... Bioorganic & Medicinal Chemistry Letters 20 (5), 1763-1766, 2010 | 53 | 2010 |
| Monooxime‐monocarbamoyl bispyridinium xylene‐linked reactivators of acetylcholinesterase—synthesis, in vitro and toxicity evaluation, and docking studies K Musilek, O Holas, J Misik, M Pohanka, L Novotny, V Dohnal, ... ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 247-254, 2010 | 53 | 2010 |
| Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers S Hamulakova, J Imrich, L Janovec, P Kristian, I Danihel, O Holas, ... International journal of biological macromolecules 70, 435-439, 2014 | 52 | 2014 |
| Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage–implications for early Myasthenia gravis treatment K Musilek, M Komloova, O Holas, M Hrabinova, M Pohanka, V Dohnal, ... European Journal of Medicinal Chemistry 46 (2), 811-818, 2011 | 48 | 2011 |
| Mycobacterium tuberculosis enoyl-acyl carrier protein reductase inhibitors as potential antituberculotics: development in the past decade O Holas, P Ondrejcek, M Dolezal Journal of enzyme inhibition and medicinal chemistry 30 (4), 629-648, 2015 | 47 | 2015 |
| Synthesis of bispyridinium compounds bearing propane linker and evaluation of their reactivation activity against tabun-and paraoxon-inhibited acetylcholinesterase K Musilek, O Holas, J Hambalek, K Kuca, D Jun, V Dohnal, M Dolezal Letters in Organic Chemistry 3 (11), 831-835, 2006 | 46 | 2006 |
| Nanomaterials for direct and indirect immunomodulation: A review of applications J Kubackova, J Zbytovska, O Holas European Journal of Pharmaceutical Sciences 142, 105139, 2020 | 43 | 2020 |
| Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors—implications for early Myasthenia gravis treatment M Komloova, K Musilek, A Horova, O Holas, V Dohnal, F Gunn-Moore, ... Bioorganic & Medicinal Chemistry Letters 21 (8), 2505-2509, 2011 | 43 | 2011 |
| Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase K Musilek, O Holas, K Kuca, D Jun, V Dohnal, M Dolezal Bioorganic & medicinal chemistry letters 16 (21), 5673-5676, 2006 | 43 | 2006 |
| Synthesis of novel pyrazinamide derivatives based on 3-chloropyrazine-2-carboxamide and their antimicrobial evaluation O Jandourek, M Tauchman, P Paterova, K Konecna, L Navratilova, ... Molecules 22 (2), 223, 2017 | 36 | 2017 |
