Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer M Luu, Z Riester, A Baldrich, N Reichardt, S Yuille, A Busetti, M Klein, ... Nature communications 12 (1), 4077, 2021 | 411 | 2021 |
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes M Luu, S Pautz, V Kohl, R Singh, R Romero, S Lucas, J Hofmann, ... Nature communications 10 (1), 760, 2019 | 391 | 2019 |
Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate M Luu, K Weigand, F Wedi, C Breidenbend, H Leister, S Pautz, T Adhikary, ... Scientific reports 8 (1), 14430, 2018 | 280 | 2018 |
The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4+ T Cells M Kespohl, N Vachharajani, M Luu, H Harb, S Pautz, S Wolff, N Sillner, ... Frontiers in immunology 8, 1036, 2017 | 262 | 2017 |
Short‐chain fatty acids: bacterial messengers modulating the immunometabolism of T cells M Luu, A Visekruna European Journal of Immunology 49 (6), 842-848, 2019 | 154 | 2019 |
Exploring the molecular mechanisms underlying the protective effects of microbial SCFAs on intestinal tolerance and food allergy M Luu, H Monning, A Visekruna Frontiers in immunology 11, 1225, 2020 | 98 | 2020 |
The role of short-chain fatty acids and bile acids in intestinal and liver function, inflammation, and carcinogenesis A Visekruna, M Luu Frontiers in Cell and Developmental Biology 9, 703218, 2021 | 94 | 2021 |
Functional heterogeneity of gut‐resident regulatory T cells M Luu, U Steinhoff, A Visekruna Clinical & translational immunology 6 (9), e156, 2017 | 85 | 2017 |
Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia H Jetani, A Navarro-Bailón, M Maucher, S Frenz, C Verbruggen, ... Blood, The Journal of the American Society of Hematology 138 (19), 1830-1842, 2021 | 73 | 2021 |
Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells A Lopez Krol, HP Nehring, FF Krause, A Wempe, H Raifer, A Nist, ... EMBO reports 23 (12), e54685, 2022 | 67 | 2022 |
Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7 N Vachharajani, T Joeris, M Luu, S Hartmann, S Pautz, E Jenike, ... Oncotarget 8 (31), 50447, 2017 | 63 | 2017 |
Dietary cellulose induces anti-inflammatory immunity and transcriptional programs via maturation of the intestinal microbiota F Fischer, R Romero, A Hellhund, U Linne, W Bertrams, O Pinkenburg, ... Gut Microbes 12 (1), 1829962, 2020 | 60 | 2020 |
Time to evolve: predicting engineered T cell-associated toxicity with next-generation models E Donnadieu, M Luu, M Alb, B Anliker, S Arcangeli, C Bonini, ... Journal for immunotherapy of cancer 10 (5), e003486, 2022 | 44 | 2022 |
Lymphodepletion–an essential but undervalued part of the chimeric antigen receptor T-cell therapy cycle B Lickefett, L Chu, V Ortiz-Maldonado, L Warmuth, P Barba, M Doglio, ... Frontiers in immunology 14, 1303935, 2023 | 40 | 2023 |
Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation T Preglej, P Hamminger, M Luu, T Bulat, L Andersen, L Göschl, V Stolz, ... JCI insight 5 (4), e133393, 2020 | 38 | 2020 |
Pro-and antitumorigenic capacity of immunoproteasomes in shaping the tumor microenvironment H Leister, M Luu, D Staudenraus, A Lopez Krol, HJ Mollenkopf, A Sharma, ... Cancer immunology research 9 (6), 682-692, 2021 | 27 | 2021 |
The impact of gut microbiota-derived metabolites on the tumor immune microenvironment M Luu, B Schütz, M Lauth, A Visekruna Cancers 15 (5), 1588, 2023 | 26 | 2023 |
Intestinal development and homeostasis require activation and apoptosis of diet-reactive T cells A Visekruna, S Hartmann, YR Sillke, R Glauben, F Fischer, H Raifer, ... The Journal of clinical investigation 129 (5), 1972-1983, 2019 | 26 | 2019 |
Time 2EVOLVE: predicting efficacy of engineered T-cells–how far is the bench from the bedside? S Guedan, M Luu, D Ammar, P Barbao, C Bonini, P Bousso, CJ Buchholz, ... Journal for Immunotherapy of Cancer 10 (5), e003487, 2022 | 23 | 2022 |
Microbial metabolites: novel therapeutic tools for boosting cancer therapies M Luu, A Visekruna Trends in Cell Biology 31 (11), 873-875, 2021 | 19 | 2021 |