RNF4 is required for DNA double-strand break repair in vivo R Vyas, R Kumar, F Clermont, A Helfricht, P Kalev, P Sotiropoulou, ... Cell Death & Differentiation 20 (3), 490-502, 2013 | 133 | 2013 |
The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery R Kumar, R González-Prieto, Z Xiao, M Verlaan-de Vries, ACO Vertegaal Nature communications 8 (1), 1809, 2017 | 129 | 2017 |
c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4 R González-Prieto, SAG Cuijpers, R Kumar, IA Hendriks, ACO Vertegaal Cell cycle 14 (12), 1859-1872, 2015 | 109 | 2015 |
p53 maintains genomic stability by preventing interference between transcription and replication CQX Yeo, I Alexander, Z Lin, S Lim, OA Aning, R Kumar, ... Cell reports 15 (1), 132-146, 2016 | 106 | 2016 |
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers R Kumar, L Coronel, B Somalanka, A Raju, OA Aning, O An, YS Ho, ... Nature communications 9 (1), 3931, 2018 | 87 | 2018 |
Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle–regulated by CDK1 activity M Granata, F Lazzaro, D Novarina, D Panigada, F Puddu, CM Abreu, ... PLoS genetics 6 (8), e1001047, 2010 | 87 | 2010 |
RIF1: a novel regulatory factor for DNA replication and DNA damage response signaling R Kumar, CF Cheok DNA repair 15, 54-59, 2014 | 79 | 2014 |
Therapeutic targeting of TEAD transcription factors in cancer AV Pobbati, R Kumar, BP Rubin, W Hong Trends in Biochemical Sciences, 2023 | 72 | 2023 |
Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1 CM Abreu, R Kumar, D Hamilton, AW Dawdy, K Creavin, S Eivers, K Finn, ... PLoS genetics 9 (4), e1003310, 2013 | 48 | 2013 |
RNF4—a paradigm for SUMOylation‐mediated ubiquitination R Kumar, K Sabapathy Proteomics 19 (21-22), 1900185, 2019 | 37 | 2019 |
Dynamics of RIF1 SUMOylation is regulated by PIAS4 in the maintenance of Genomic Stability R Kumar, CF Cheok Scientific Reports 7 (1), 17367, 2017 | 20 | 2017 |
Hippo Signaling at the Hallmarks of Cancer and Drug Resistance R KUMAR, W Hong Cells, 2024 | 10 | 2024 |
Abstract LB033: Identification of small molecule Pan-TEAD inhibitors disrupting YAP-TEAD protein-protein interaction and targeting gastric cancer cells R Kumar, J Toh, J Thian, NF Mohideen, J Sun, S Chakraborty, ... Cancer Research 84 (7_Supplement), LB033-LB033, 2024 | | 2024 |
Tead targeting compounds and methods thereof RK Dewei Joel TOH, Wanjin Hong SG Patent WO2023224545A2, 2023 | | 2023 |
Use of niclosamide in the treatment of p53-deficient cells RK Chit Fang Cheok US Patent WO/2,017,048,197, 2017 | | 2017 |
Role of Rad9 cell cycle phosphorylation in the regulation of Chk1 activation R Kumar National University of Ireland, Galway, 2012 | | 2012 |