| Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor QA Rafiq, KM Brosnan, K Coopman, AW Nienow, CJ Hewitt Biotechnology letters 35, 1233-1245, 2013 | 234 | 2013 |
| A potentially scalable method for the harvesting of hMSCs from microcarriers AW Nienow, QA Rafiq, K Coopman, CJ Hewitt Biochemical Engineering Journal 85, 79-88, 2014 | 190 | 2014 |
| Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors QA Rafiq, K Coopman, AW Nienow, CJ Hewitt Biotechnology journal 11 (4), 473-486, 2016 | 175 | 2016 |
| Antimicrobial resistance mechanisms and potential synthetic treatments J Ali, QA Rafiq, E Ratcliffe Future science OA 4 (4), FSO290, 2018 | 160 | 2018 |
| Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum‐free microcarrier process TRJ Heathman, VAM Glyn, A Picken, QA Rafiq, K Coopman, AW Nienow, ... Biotechnology and bioengineering 112 (8), 1696-1707, 2015 | 113 | 2015 |
| Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms AW Nienow, CJ Hewitt, TRJ Heathman, VAM Glyn, GN Fonte, MP Hanga, ... Biochemical Engineering Journal 108, 24-29, 2016 | 112 | 2016 |
| Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development TRJ Heathman, QA Rafiq, AKC Chan, K Coopman, AW Nienow, B Kara, ... Biochemical engineering journal 108, 14-23, 2016 | 108 | 2016 |
| Lentiviral vectors for T cell engineering: clinical applications, bioprocessing and future perspectives RP Labbé, S Vessillier, QA Rafiq Viruses 13 (8), 1528, 2021 | 100 | 2021 |
| Scale-up of human mesenchymal stem cell culture: current technologies and future challenges QA Rafiq, K Coopman, CJ Hewitt Current Opinion in Chemical Engineering 2 (1), 8-16, 2013 | 99 | 2013 |
| Decentralised manufacturing of cell and gene therapy products: Learning from other healthcare sectors RP Harrison, S Ruck, QA Rafiq, N Medcalf Biotechnology advances 36 (2), 345-357, 2018 | 75 | 2018 |
| Decentralized manufacturing of cell and gene therapies: Overcoming challenges and identifying opportunities RP Harrison, S Ruck, N Medcalf, QA Rafiq Cytotherapy 19 (10), 1140-1151, 2017 | 73 | 2017 |
| Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds PS Couto, MC Rotondi, A Bersenev, CJ Hewitt, AW Nienow, F Verter, ... Biotechnology Advances 45, 107636, 2020 | 63 | 2020 |
| Cell therapy-processing economics: small-scale microfactories as a stepping stone toward large-scale macrofactories RP Harrison, N Medcalf, QA Rafiq Regenerative medicine 13 (2), 159-173, 2018 | 59 | 2018 |
| Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production TRJ Heathman, A Stolzing, C Fabian, QA Rafiq, K Coopman, AW Nienow, ... Cytotherapy 17 (11), 1524-1535, 2015 | 57 | 2015 |
| Process development of human multipotent stromal cell microcarrier culture using an automated high‐throughput microbioreactor QA Rafiq, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ... Biotechnology and bioengineering 114 (10), 2253-2266, 2017 | 56 | 2017 |
| Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: Utilising the phenomenon to improve … QA Rafiq, S Ruck, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ... Biochemical Engineering Journal 135, 11-21, 2018 | 55 | 2018 |
| Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate TRJ Heathman, A Stolzing, C Fabian, QA Rafiq, K Coopman, AW Nienow, ... Cytotherapy 18 (4), 523-535, 2016 | 55 | 2016 |
| Centralised versus decentralised manufacturing and the delivery of healthcare products: A United Kingdom exemplar RP Harrison, QA Rafiq, N Medcalf Cytotherapy 20 (6), 873-890, 2018 | 51 | 2018 |
| Demonstrating the manufacture of human CAR‐T cells in an automated stirred‐tank bioreactor E Costariol, MC Rotondi, A Amini, CJ Hewitt, AW Nienow, TRJ Heathman, ... Biotechnology Journal 15 (9), 2000177, 2020 | 46 | 2020 |
| Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development TRJ Heathman, AW Nienow, QA Rafiq, K Coopman, B Kara, CJ Hewitt Biochemical Engineering Journal 136, 9-17, 2018 | 44 | 2018 |
Alvin NienowUniversity of BirminghamPreverjeni e-poštni naslov na bham.ac.uk