Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes PA VanderLaan, D Rangachari, SM Mockus, V Spotlow, HV Reddi, ... Lung cancer 106, 17-21, 2017 | 186 | 2017 |
A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer AH Wagner, B Walsh, G Mayfield, D Tamborero, D Sonkin, K Krysiak, ... Nature genetics 52 (4), 448-457, 2020 | 141 | 2020 |
The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies SE Patterson, R Liu, CM Statz, D Durkin, A Lakshminarayana, SM Mockus Human genomics 10, 1-13, 2016 | 139 | 2016 |
Advances in the molecular characterization of tryptophan hydroxylase SM Mockus, KE Vrana Journal of Molecular Neuroscience 10, 163-179, 1998 | 125 | 1998 |
Cisplatin-resistant triple-negative breast cancer subtypes: multiple mechanisms of resistance DP Hill, A Harper, J Malcolm, MS McAndrews, SM Mockus, SE Patterson, ... BMC cancer 19, 1-13, 2019 | 121 | 2019 |
Mechanism of SNARE protein binding and regulation of Cav2 channels by phosphorylation of the synaptic protein interaction site CT Yokoyama, SJ Myers, J Fu, SM Mockus, T Scheuer, WA Catterall Molecular and Cellular Neuroscience 28 (1), 1-17, 2005 | 96 | 2005 |
mTOR inhibitors in castration-resistant prostate cancer: a systematic review CM Statz, SE Patterson, SM Mockus Targeted oncology 12, 47-59, 2017 | 73 | 2017 |
Amino‐terminal analysis of tryptophan hydroxylase: protein kinase phosphorylation occurs at serine‐58 SC Kumer, SM Mockus, PJ Rucker, KE Vrana Journal of neurochemistry 69 (4), 1738-1745, 1997 | 51 | 1997 |
Molecular genetic analysis of ovarian Brenner tumors and associated mucinous epithelial neoplasms: high variant concordance and identification of mutually exclusive RAS driver … LJ Tafe, KE Muller, G Ananda, T Mitchell, V Spotlow, SE Patterson, ... The American Journal of Pathology 186 (3), 671-677, 2016 | 43 | 2016 |
Standardizing gene product nomenclature—a call to action K Fujiyoshi, EA Bruford, P Mroz, CL Sims, TJ O’Leary, AWI Lo, N Chen, ... Proceedings of the National Academy of Sciences 118 (3), e2025207118, 2021 | 41 | 2021 |
Utility of the JAX Clinical Knowledgebase in capture and assessment of complex genomic cancer data SE Patterson, CM Statz, T Yin, SM Mockus npj Precision Oncology 3 (1), 2, 2019 | 36 | 2019 |
Development and validation of the JAX Cancer Treatment Profile™ for detection of clinically actionable mutations in solid tumors G Ananda, S Mockus, M Lundquist, V Spotlow, A Simons, T Mitchell, ... Experimental and molecular pathology 98 (1), 106-112, 2015 | 35 | 2015 |
Somatic gene mutation analysis of triple negative breast cancers JL Dillon, SM Mockus, G Ananda, V Spotlow, WA Wells, GJ Tsongalis, ... The Breast 29, 202-207, 2016 | 32 | 2016 |
Carboxyl terminal deletion analysis of tryptophan hydroxylase SM Mockus, SC Kumer, KE Vrana Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1997 | 31 | 1997 |
A chimeric tyrosine/tryptophan hydroxylase: The tyrosine hydroxylase regulatory domain serves to stabilize enzyme activity SM Mockus, SC Kumer, KE Vrana Journal of Molecular Neuroscience 9, 35-48, 1997 | 26 | 1997 |
Human genome meeting 2016 AK Srivastava, Y Wang, R Huang, C Skinner, T Thompson, L Pollard, ... Human Genomics 10 (1), 12, 2016 | 25* | 2016 |
A harmonized meta-knowledgebase of clinical interpretations of cancer genomic variants AH Wagner, B Walsh, G Mayfield, D Tamborero, D Sonkin, K Krysiak, ... BioRxiv, 366856, 2018 | 21 | 2018 |
High-resolution deconstruction of evolution induced by chemotherapy treatments in breast cancer xenografts H Kim, P Kumar, F Menghi, J Noorbakhsh, E Cerveira, M Ryan, Q Zhu, ... Scientific reports 8 (1), 17937, 2018 | 17 | 2018 |
Intersubunit binding domains within tyrosine hydroxylase and tryptophan hydroxylase GJ Yohrling IV, GCT Jiang, SM Mockus, KE Vrana Journal of neuroscience research 61 (3), 313-320, 2000 | 16 | 2000 |
Identification of amino-terminal sequences contributing to tryptophan hydroxylase tetramer formation GJ Yohrling, SM Mockus, KE Vrana Journal of Molecular Neuroscience 12, 23-34, 1999 | 15 | 1999 |