| High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1727 | 2015 |
| Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017 | 563 | 2017 |
| CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ... Nature 559 (7713), 285-289, 2018 | 389 | 2018 |
| Functional genomic landscape of cancer-intrinsic evasion of killing by T cells KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ... Nature 586 (7827), 120-126, 2020 | 348 | 2020 |
| Massive production of small RNAs from a non-coding region of Cauliflower mosaic virus in plant defense and viral counter-defense T Blevins, R Rajeswaran, M Aregger, BK Borah, M Schepetilnikov, ... Nucleic Acids Research 39 (12), 5003-5014, 2011 | 191 | 2011 |
| Primary and secondary siRNAs in geminivirus-induced gene silencing M Aregger, BK Borah, J Seguin, R Rajeswaran, EG Gubaeva, AS Zvereva, ... PLoS Pathogens 8 (9), e1002941, 2012 | 187 | 2012 |
| Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform T Gonatopoulos-Pournatzis, M Aregger, KR Brown, S Farhangmehr, ... Nature Biotechnology 38 (5), 638-648, 2020 | 132 | 2020 |
| Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons T Gonatopoulos-Pournatzis, M Wu, U Braunschweig, J Roth, H Han, ... Molecular Cell 72 (3), 510-524. e12, 2018 | 118 | 2018 |
| Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism M Aregger, KA Lawson, M Billmann, M Costanzo, AHY Tong, K Chan, ... Nature Metabolism 2 (6), 499-513, 2020 | 91 | 2020 |
| Sequencing of RDR6-dependent double-stranded RNAs reveals novel features of plant siRNA biogenesis R Rajeswaran, M Aregger, AS Zvereva, BK Borah, EG Gubaeva, ... Nucleic Acids Research 40 (13), 6241-6254, 2012 | 67 | 2012 |
| CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription M Aregger, A Kaskar, D Varshney, ME Fernandez-Sanchez, ... Molecular Cell 61 (5), 734-746, 2016 | 53 | 2016 |
| Pooled Lentiviral CRISPR-Cas9 Screens for Functional Genomics in Mammalian Cells M Aregger, M Chandrashekhar, AHY Tong, K Chan, J Moffat Brain Tumor Stem Cells, 169-188, 2019 | 43 | 2019 |
| Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites M Aregger, VH Cowling Biochemical Journal 455 (1), 67-73, 2013 | 38 | 2013 |
| LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions SA Serra, P Stojakovic, R Amat, F Rubio-Moscardo, P Latorre, ... Proceedings of the National Academy of Sciences 118 (23), e2025013118, 2021 | 34 | 2021 |
| Regulation of mRNA capping in the cell cycle M Aregger, VH Cowling RNA Biology 14 (1), 11-14, 2017 | 26 | 2017 |
| E2F1-dependent methyl cap formation requires RNA pol II phosphorylation M Aregger, VH Cowling Cell Cycle 11 (11), 2146-2148, 2012 | 16 | 2012 |
| Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline HN Ward, M Aregger, T Gonatopoulos-Pournatzis, M Billmann, ... Nature Protocols 16 (10), 4766-4798, 2021 | 14 | 2021 |
| Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening M Aregger, K Xing, T Gonatopoulos-Pournatzis Nature Protocols 16 (10), 4722-4765, 2021 | 12 | 2021 |
| A method for benchmarking genetic screens reveals a predominant mitochondrial bias M Rahman, M Billmann, M Costanzo, M Aregger, AHY Tong, K Chan, ... Molecular Systems Biology 17 (5), e10013, 2021 | 12 | 2021 |
| Abrogation of the G2/M checkpoint as a chemo sensitization approach for alkylating agents F Lang, JA Cornwell, K Kaur, O Elmogazy, W Zhang, M Zhang, H Song, ... Neuro-oncology, noad252, 2023 | 9 | 2023 |
Jason MoffatSenior Scientist & Program Head, Genetics & Genome Biology, Sickkids Hospital; Professor, UofTPreverjeni e-poštni naslov na utoronto.ca
