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Bernhard Lehnertz
Bernhard Lehnertz
ExCellThera Inc.
Preverjeni e-poštni naslov na excellthera.com
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Leto
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
B Lehnertz, Y Ueda, AAHA Derijck, U Braunschweig, L Perez-Burgos, ...
Current Biology 13 (14), 1192-1200, 2003
15232003
Mubritinib targets the electron transport chain complex I and reveals the landscape of OXPHOS dependency in acute myeloid leukemia
I Baccelli, Y Gareau, B Lehnertz, S Gingras, JF Spinella, S Corneau, ...
Cancer cell 36 (1), 84-99. e8, 2019
2292019
Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1–2 safety and feasibility study
S Cohen, J Roy, S Lachance, JS Delisle, A Marinier, L Busque, DC Roy, ...
The Lancet Haematology 7 (2), e134-e145, 2020
2132020
EPCR expression marks UM171-expanded CD34+ cord blood stem cells
I Fares, J Chagraoui, B Lehnertz, T MacRae, N Mayotte, E Tomellini, ...
Blood, The Journal of the American Society of Hematology 129 (25), 3344-3351, 2017
2082017
Control of the hippo pathway by Set7-dependent methylation of Yap
MJ Oudhoff, SA Freeman, AL Couzens, F Antignano, E Kuznetsova, ...
Developmental cell 26 (2), 188-194, 2013
1922013
Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function
B Lehnertz, JP Northrop, F Antignano, K Burrows, S Hadidi, SC Mullaly, ...
Journal of Experimental Medicine 207 (5), 915-922, 2010
1782010
The methyltransferase G9a regulates HoxA9-dependent transcription in AML
B Lehnertz, C Pabst, L Su, M Miller, F Liu, L Yi, R Zhang, J Krosl, E Yung, ...
Genes & development 28 (4), 317-327, 2014
1652014
Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing
DC Leung, KB Dong, IA Maksakova, P Goyal, R Appanah, S Lee, ...
Proceedings of the National Academy of Sciences 108 (14), 5718-5723, 2011
1472011
p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice
B Lehnertz, JC Rogalski, FM Schulze, L Yi, S Lin, J Kast, FMV Rossi
Molecular cell 43 (4), 673-680, 2011
892011
Genetic characterization of ABT-199 sensitivity in human AML
R Bisaillon, C Moison, C Thiollier, J Krosl, ME Bordeleau, B Lehnertz, ...
Leukemia 34 (1), 63-74, 2020
882020
H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations
B Lehnertz, YW Zhang, I Boivin, N Mayotte, E Tomellini, J Chagraoui, ...
Blood, The Journal of the American Society of Hematology 130 (20), 2204-2214, 2017
812017
Integrin-α3 is a functional marker of ex vivo expanded human long-term hematopoietic stem cells
E Tomellini, I Fares, B Lehnertz, J Chagraoui, N Mayotte, T MacRae, ...
Cell Reports 28 (4), 1063-1073. e5, 2019
692019
HLF expression defines the human hematopoietic stem cell state
B Lehnertz, J Chagraoui, T MacRae, E Tomellini, S Corneau, N Mayotte, ...
Blood, The Journal of the American Society of Hematology 138 (25), 2642-2654, 2021
602021
UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal
J Chagraoui, B Lehnertz, S Girard, JF Spinella, I Fares, E Tomellini, ...
PLoS One 14 (11), e0224900, 2019
582019
Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity
L Simon, VP Lavallée, ME Bordeleau, J Krosl, I Baccelli, G Boucher, ...
Clinical cancer research 23 (22), 6969-6981, 2017
532017
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells
YW Zhang, J Mess, N Aizarani, P Mishra, C Johnson, MC Romero-Mulero, ...
Nature Cell Biology 24 (7), 1038-1048, 2022
512022
Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition
C Moison, VP Lavallée, C Thiollier, B Lehnertz, I Boivin, N Mayotte, ...
Blood advances 3 (4), 552-563, 2019
332019
Methyltransferase G9A Regulates Osteogenesis via Twist Gene Repression
N Higashihori, B Lehnertz, A Sampaio, TM Underhill, F Rossi, ...
Journal of dental research 96 (10), 1136-1144, 2017
272017
UBAP2L is amplified in a large subset of human lung adenocarcinoma and is critical for epithelial lung cell identity and tumor metastasis
R Aucagne, S Girard, N Mayotte, B Lehnertz, S Lopes‐Paciencia, ...
The FASEB Journal 31 (11), 5012-5018, 2017
202017
HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition
C Moison, JF Spinella, J Chagraoui, VP Lavallée, B Lehnertz, C Thiollier, ...
Blood Advances 6 (16), 4793-4806, 2022
122022
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