Interlaboratory reproducibility of a targeted metabolomics platform for analysis of human serum and plasma AP Siskos, P Jain, W Romisch-Margl, M Bennett, D Achaintre, Y Asad, ... Analytical chemistry 89 (1), 656-665, 2017 | 277 | 2017 |
Human Early Life Exposome (HELIX) study: a European population-based exposome cohort L Maitre, J De Bont, M Casas, O Robinson, GM Aasvang, L Agier, ... BMJ open 8 (9), e021311, 2018 | 229 | 2018 |
Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases AP Siskos, A Baerga-Ortiz, S Bali, V Stein, H Mamdani, D Spiteller, ... Chemistry & biology 12 (10), 1145-1153, 2005 | 148 | 2005 |
Determinants of the urinary and serum metabolome in children from six European populations CHE Lau, AP Siskos, L Maitre, O Robinson, TJ Athersuch, EJ Want, ... BMC medicine 16, 1-19, 2018 | 137 | 2018 |
Directed mutagenesis alters the stereochemistry of catalysis by isolated ketoreductase domains from the erythromycin polyketide synthase A Baerga-Ortiz, B Popovic, AP Siskos, HM O'Hare, D Spiteller, ... Chemistry & biology 13 (3), 277-285, 2006 | 127 | 2006 |
Prenatal exposure to perfluoroalkyl substances associated with increased susceptibility to liver injury in children N Stratakis, D V. Conti, R Jin, K Margetaki, D Valvi, AP Siskos, L Maitre, ... Hepatology 72 (5), 1758-1770, 2020 | 123 | 2020 |
Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis SP Allen, B Hall, LM Castelli, L Francis, R Woof, AP Siskos, E Kouloura, ... Brain 142 (3), 586-605, 2019 | 120 | 2019 |
Multi-omics signatures of the human early life exposome L Maitre, M Bustamante, C Hernández-Ferrer, D Thiel, CHE Lau, ... Nature communications 13 (1), 7024, 2022 | 105 | 2022 |
Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis R Anderson, A Franch, M Castell, FJ Perez-Cano, R Bräuer, D Pohlers, ... Arthritis research & therapy 12, 1-15, 2010 | 99 | 2010 |
Peptide and protein drugs: the study of their metabolism and catabolism by mass spectrometry T Katsila, AP Siskos, C Tamvakopoulos Mass spectrometry reviews 31 (1), 110-133, 2012 | 86 | 2012 |
Metabolomic analysis reveals increased aerobic glycolysis and amino acid deficit in a cellular model of amyotrophic lateral sclerosis GN Valbuena, M Rizzardini, S Cimini, AP Siskos, C Bendotti, L Cantoni, ... Molecular neurobiology 53, 2222-2240, 2016 | 85 | 2016 |
Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention JA Miller, K Pappan, PA Thompson, EJ Want, AP Siskos, HC Keun, J Wulff, ... Cancer Prevention Research 8 (1), 86-93, 2015 | 60 | 2015 |
Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview M Vrijheid, X Basagaña, JR Gonzalez, VWV Jaddoe, G Jensen, HC Keun, ... Environmental Epidemiology 5 (5), e166, 2021 | 53 | 2021 |
Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking P Georgiadis, DG Hebels, I Valavanis, I Liampa, IA Bergdahl, ... Scientific reports 6 (1), 20544, 2016 | 38 | 2016 |
Prospective analysis of circulating metabolites and endometrial cancer risk L Dossus, E Kouloura, C Biessy, V Viallon, AP Siskos, N Dimou, S Rinaldi, ... Gynecologic oncology 162 (2), 475-481, 2021 | 37 | 2021 |
Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells EME Barnes, Y Xu, A Benito, L Herendi, AP Siskos, EO Aboagye, ... British journal of cancer 122 (9), 1298-1308, 2020 | 36 | 2020 |
Assessment of metabolic phenotypic variability in children’s urine using 1H NMR spectroscopy L Maitre, CHE Lau, E Vizcaino, O Robinson, M Casas, AP Siskos, ... Scientific Reports 7 (1), 46082, 2017 | 36 | 2017 |
Chain initiation on type I modular polyketide synthases revealed by limited proteolysis and ion‐trap mass spectrometry H Hong, AN Appleyard, AP Siskos, J Garcia‐Bernardo, J Staunton, ... The FEBS journal 272 (10), 2373-2387, 2005 | 33 | 2005 |
Variability of multi-omics profiles in a population-based child cohort M Gallego-Paüls, C Hernández-Ferrer, M Bustamante, X Basagaña, ... BMC medicine 19, 1-16, 2021 | 32 | 2021 |
Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs P Saavedra-García, M Roman-Trufero, HA Al-Sadah, K Blighe, ... Proceedings of the National Academy of Sciences 118 (17), e2018229118, 2021 | 30 | 2021 |