| Stochasticity in gene expression: from theories to phenotypes M Kærn, TC Elston, WJ Blake, JJ Collins Nature Reviews Genetics 6 (6), 451-464, 2005 | 2823 | 2005 |
| Noise in eukaryotic gene expression WJ Blake, M Kærn, CR Cantor, JJ Collins Nature 422 (6932), 633-637, 2003 | 2010 | 2003 |
| Phenotypic consequences of promoter-mediated transcriptional noise WJ Blake, G Balázsi, MA Kohanski, FJ Isaacs, KF Murphy, Y Kuang, ... Molecular cell 24 (6), 853-865, 2006 | 737 | 2006 |
| Synthetic chromosome arms function in yeast and generate phenotypic diversity by design JS Dymond, SM Richardson, CE Coombes, T Babatz, H Muller, ... Nature 477 (7365), 471-476, 2011 | 565 | 2011 |
| Origins of extrinsic variability in eukaryotic gene expression D Volfson, J Marciniak, WJ Blake, N Ostroff, LS Tsimring, J Hasty Nature 439 (7078), 861-864, 2006 | 351 | 2006 |
| The engineering of gene regulatory networks M Kaern, WJ Blake, JJ Collins Annual review of biomedical engineering 5 (1), 179-206, 2003 | 273 | 2003 |
| Iterative nucleic acid assembly using activation of vector-encoded traits WJ Blake US Patent 8,053,191, 2011 | 76 | 2011 |
| Iterative nucleic acid assembly using activation of vector-encoded traits WJ Blake US Patent 10,202,608, 2019 | 73 | 2019 |
| Pairwise selection assembly for sequence-independent construction of long-length DNA WJ Blake, BA Chapman, A Zindal, ME Lee, SM Lippow, BM Baynes Nucleic acids research 38 (8), 2594-2602, 2010 | 57 | 2010 |
| Creation of a type IIS restriction endonuclease with a long recognition sequence SM Lippow, PM Aha, MH Parker, WJ Blake, BM Baynes, D Lipovšek Nucleic acids research 37 (9), 3061-3073, 2009 | 53 | 2009 |
| Synthetic biology evolves WJ Blake, FJ Isaacs TRENDS in Biotechnology 22 (7), 321-324, 2004 | 36 | 2004 |
| Nucleic acid assembly optimization using clamped mismatch binding proteins B Baynes, W Blake US Patent App. 11/394,708, 2007 | 33 | 2007 |
| Cell-free system for converting methane into fuel and chemical compounds WJ Blake, JR Swartz US Patent 9,611,487, 2017 | 18 | 2017 |
| Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes EA Phillips, AD Silverman, A Joneja, M Liu, C Brown, P Carlson, ... Nature Biomedical Engineering 7 (12), 1571-1582, 2023 | 16 | 2023 |
| High-throughput CRISPR–Cas13 SARS-CoV-2 test BJ Manning, WA Khan, JM Peña, ES Fiore, H Boisvert, MC Tudino, ... Clinical Chemistry 68 (1), 172-180, 2022 | 16 | 2022 |
| Cell-free preparation of carbapenems WJ Blake, D Klein-Marcuschamer US Patent 9,469,861, 2016 | 16 | 2016 |
| Engineered phosphoglucose isomerase proteins with a protease cleavage site WJ Blake, DS Cunningham US Patent 9,688,977, 2017 | 15* | 2017 |
| Signal processing in single cells FJ Isaacs, WJ Blake, JJ Collins Science 307 (5717), 1886-1888, 2005 | 15 | 2005 |
| Cell-free production of ribonucleic acid WJ Blake, DS Cunningham, D MacEachran, M Gupta, JR Abshire US Patent 10,954,541, 2021 | 14 | 2021 |
| Real-time, multiplexed SHERLOCK for in vitro diagnostics JM Pena, BJ Manning, X Li, ES Fiore, L Carlson, K Shytle, PP Nguyen, ... The Journal of Molecular Diagnostics 25 (7), 428-437, 2023 | 12 | 2023 |
